LYXUMIA 20 PRE FILLED PEN INJECTION

Written By Divya L , PharmaD

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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MRP ₹4114

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₹617.1 Cashback (15%)

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Whats That

About LYXUMIA 20 PRE FILLED PEN INJECTION

LYXUMIA 20 PRE FILLED PEN INJECTION belongs to the class of 'anti-diabetic medicines' primarily used to improve blood sugar control in adults with type 2 diabetes mellitus (non-insulin-dependent diabetes). Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all.

LYXUMIA 20 PRE FILLED PEN INJECTION contains 'Lixisenatide' that belongs to the class of 'incretin mimetics'. Lixisenatide works by increasing insulin release from the pancreas during high blood sugar levels and decreasing the hormones that raise the concentration of blood glucose levels.

Your doctor will decide the dose and duration based on your medical condition. Some common side effects of LYXUMIA 20 PRE FILLED PEN INJECTION include headache, nausea, vomiting, diarrhoea, dizziness, upset stomach, constipation, and injection site reactions like pain/swelling/itching. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before starting LYXUMIA 20 PRE FILLED PEN INJECTION , let your doctor know if you have a history of heart, kidney or liver diseases. Do not take or stop this medicine if the doctor did not advise you. It is advised to limit your alcohol intake while using LYXUMIA 20 PRE FILLED PEN INJECTION to avoid low blood sugar levels further. Pregnant and breastfeeding women should consult their doctor before starting LYXUMIA 20 PRE FILLED PEN INJECTION . LYXUMIA 20 PRE FILLED PEN INJECTION may cause hypoglycaemia (low blood sugar levels) and dizziness affecting your driving ability; hence drive or operate machinery only when you feel better. LYXUMIA 20 PRE FILLED PEN INJECTION is not recommended for children and adolescents under 18 years of age.

Uses of LYXUMIA 20 PRE FILLED PEN INJECTION

Type 2 Diabetes mellitus.

Directions for Use

Injection pen: Use the injection solution only if it is clear, colourless, and contains no particles. The injection is administered subcutaneously (under the skin) in the abdomen, thigh or upper arm. Your doctor or nurse will guide you on how to use the injection pen. Store the LYXUMIA 20 PRE FILLED PEN INJECTION in a refrigerator at 2°C-8 °C. Do not freeze it.

Medicinal Benefits

LYXUMIA 20 PRE FILLED PEN INJECTION comprises 'Lixisenatide.' It is an incretin mimetic that mimics the action of a natural hormone called Incretin (metabolic hormone, which stimulates a decrease in blood glucose levels). It works by increasing insulin release from the pancreas during high blood sugar levels (after meals) and decreases the amount of sugar the liver makes. LYXUMIA 20 PRE FILLED PEN INJECTION is used as an adjunct to diet and exercise to improve glycaemic control.

Storage

Keep out of sight and reach of children.

Side effects of Lyxumia 20 Pre Filled Pen Injection

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Injection site pain/discomfort

Low Blood Sugar

If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
Make medication adjustments as recommended by your doctor to prevent future episodes.
Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
Monitor your blood sugar levels closely for patterns and changes.
Track your progress by recording your blood sugar levels, food intake, and physical activity.
Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

Drug Warnings

Brief your medical history to the doctor if you have any heart, kidney or liver diseases, pancreatitis (inflammation of the pancreas), dehydration, digestion problems, gall stones, gastroparesis (delayed gastric emptying), hypoglycaemia (low blood sugar levels), or type 1 diabetes before starting LYXUMIA 20 PRE FILLED PEN INJECTION . Do not share an injection pen, cartridge, or syringe with another person, even if the needle is changed. It is advised to limit your alcohol intake while using LYXUMIA 20 PRE FILLED PEN INJECTION to avoid low blood sugar levels further. Pregnant and breastfeeding women should consult their doctor before starting this medication. LYXUMIA 20 PRE FILLED PEN INJECTION may make you feel dizzy, hence drive and operate machinery only when you feel better. LYXUMIA 20 PRE FILLED PEN INJECTION is not recommended for children and adolescents under 18 years of age.

Drug-Drug Interactions

LixisenatideGatifloxacin

Critical

Drug-Drug Interactions

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LixisenatideGatifloxacin

Critical

How does the drug interact with Lyxumia 20 Pre Filled Pen Injection:
Coadministration of Lyxumia 20 Pre Filled Pen Injection with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Lyxumia 20 Pre Filled Pen Injection can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain blood glucose levels.
Eat at regular intervals.
Monitor your weight and exercise regularly to keep your heart healthy.
Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods and avoiding carbonated drinks and foods that cause gas.

Side Effects of LYXUMIA 20 PRE FILLED PEN INJECTION

Headache
Nausea
Vomiting
Diarrhoea
Dizziness
Upset stomach
Constipation
Injection site reactions like pain/swelling/itching

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

Written By

Divya L

PharmaD

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:48 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does LYXUMIA 20 PRE FILLED PEN INJECTION work?

LYXUMIA 20 PRE FILLED PEN INJECTION contains Lixisenatide, which increases the insulin release from the pancreas when your body has high blood glucose levels. Thus, LYXUMIA 20 PRE FILLED PEN INJECTION helps lower the blood sugar levels in type 2 diabetes mellitus.

Does LYXUMIA 20 PRE FILLED PEN INJECTION lower blood sugar levels?

LYXUMIA 20 PRE FILLED PEN INJECTION may cause low blood sugar levels (hypoglycaemia), making you hungry, dizzy, irritable, confused, anxious, or shaky. To immediately treat hypoglycaemia, eating or drinking fast-acting sugar sources like fruit juices, hard candy, raisins, or non-diet soda is advised.

Can I use LYXUMIA 20 PRE FILLED PEN INJECTION with other diabetic medications?

Your doctor may advise LYXUMIA 20 PRE FILLED PEN INJECTION with or without other anti-diabetic medications based on your blood sugar levels.

Drug-Drug Interactions Checker List

PROPRANOLOL
METOPROLOL
TIMOLOL

Special Advise

It is advised to monitor your blood sugar levels regularly.
LYXUMIA 20 PRE FILLED PEN INJECTION is not indicated for patients with type 1 diabetes or diabetic ketoacidosis.

Disease/Condition Glossary

Diabetes mellitus, or adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people above 40 years but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots.