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  3. Mac Rabonik Plus Capsule 10's

Mac Rabonik Plus Capsule 10's, Pack of 10
Mac Rabonik Plus Capsule 10's, Pack of 10
Mac Rabonik Plus Capsule 10's, Pack of 10
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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COD available

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Whats That

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Composition :

LEVOSULPIRIDE-75MG + RABEPRAZOLE-40MG

Manufacturer/Marketer :

Eris Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mac Rabonik Plus Capsule

Mac Rabonik Plus Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Mac Rabonik Plus Capsule is a combination of two drugs, namely: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Mac Rabonik Plus Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Mac Rabonik Plus Capsule may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Mac Rabonik Plus Capsule may cause drowsiness and dizziness, so drive only if you are alert. Mac Rabonik Plus Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mac Rabonik Plus Capsule as it could lead to increased drowsiness and elevate stomach acid production. 

Uses of Mac Rabonik Plus Capsule

Gastro-oesophageal reflux disease, acidity, indigestion heartburn, and peptic ulcers.

Directions for Use

Take Mac Rabonik Plus Capsule 1hour prior to food. Swallow Mac Rabonik Plus Capsule as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Mac Rabonik Plus Capsule is a combination of two drugs, namely: Rabeprazole and Levosulpiride. Mac Rabonik Plus Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Mac Rabonik Plus Capsule if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Mac Rabonik Plus Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Mac Rabonik Plus Capsule may cause dizziness and drowsiness, so drive only if you are alert. Mac Rabonik Plus Capsule is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
RabeprazoleErlotinib
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with Mac Rabonik Plus Capsule:
Co-administration of Mac Rabonik Plus Capsule can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Mac Rabonik Plus Capsule with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleErlotinib
Critical
How does the drug interact with Mac Rabonik Plus Capsule:
When used in combination with erlotinib, Mac Rabonik Plus Capsule may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Mac Rabonik Plus Capsule with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Mac Rabonik Plus Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Cisapride can increase the blood levels of Mac Rabonik Plus Capsule.

How to manage the interaction:
There may be a possibility of interaction between Mac Rabonik Plus Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Nefazodone can increase the blood levels of Mac Rabonik Plus Capsule.

How to manage the interaction:
There may be a possibility of interaction between Mac Rabonik Plus Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Combining Mizolastine with Mac Rabonik Plus Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Mac Rabonik Plus Capsule:
Coadministration of Mac Rabonik Plus Capsule with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS, ANTIULCERANTS

Mac Rabonik Plus Capsule Substitute

Substitutes safety advice

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mac Rabonik Plus Capsule contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in providing relief from acidity.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Mac Rabonik Plus Capsule contains rabeprazole which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of Mac Rabonik Plus Capsule for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.

Dry mouth could be a side-effect of Mac Rabonik Plus Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Do not take Mac Rabonik Plus Capsule for longer durations unless prescribed by the doctor. Mac Rabonik Plus Capsule might cause bone problems and hypomagnesemia on long-term treatment. Talk to your doctor if you do not find symptomatic relief despite taking Mac Rabonik Plus Capsule for 2 weeks.

Mac Rabonik Plus Capsule might cause irregular periods/abnormal menstruation. Consult your doctor if you notice abnormal bleeding patterns.

Drug-Drug Interactions Checker List

  • WARFARIN
  • METHOTREXATE
  • DIGOXIN
  • MYCOPHENOLATE MOFETIL
  • TACROLIMUS
  • AMOXICILLIN
  • CLARITHROMYCIN

Special Advise

  • Mac Rabonik Plus Capsule might cause false-positive results for secretin stimulation test, prolactin test, and tests for tetrahydrocannabinol (THC). Inform the person doing the tests that you are taking Mac Rabonik Plus Capsule .
  • Regular blood tests for monitoring magnesium levels and bone density tests are advised if you are on long-term treatment with Mac Rabonik Plus Capsule .
  • Inform your doctor if you are due to have Chromogranin A test.

Disease/Condition Glossary

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn, and peptic ulcers.

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. 

Stomach ulcers: Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea, and vomiting.

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