Macarbi CH Tablet 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Sureshvarma D , MPharma

Prescription drug

MRP ₹109

(Inclusive of all Taxes)

₹16.4 Cashback (15%)

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Whats That

About Macarbi CH Tablet

Macarbi CH Tablet belongs to the class of drugs called anti-hypertensive agents primarily used to treat high blood pressure (hypertension). Hypertension (high blood pressure) is a medical condition in which the blood pressure is elevated persistently in the arteries. High blood pressure is mostly caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing.

Macarbi CH Tablet consists of two medicines, namely: Azilsartan and Chlorthalidone. Azilsartan is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin. This helps relax the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone belongs to thiazide diuretics (water pill) which inhibits fluid retention or build-up. Thus, it relaxes the blood vessels and improves blood circulation. Together, Macarbi CH Tablet helps lower raised blood pressure.

Your doctor will decide the dosage and duration based on your medical condition. In some cases, Macarbi CH Tablet can cause side effects like nausea, taste changes, stomach upset, diarrhoea, headache, weakness, dizziness, and decreased blood pressure. Most of these side effects of Macarbi CH Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking Macarbi CH Tablet , let your doctor know if you have kidney, liver problems or severe dehydration. Avoid using Macarbi CH Tablet if you are pregnant. Breastfeeding women should consult their doctor before taking Macarbi CH Tablet . Do not consume alcohol with Macarbi CH Tablet as it may increase the risk of side effects. Avoid driving or operating machinery if you experience dizziness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Macarbi CH Tablet

Hypertension

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Macarbi CH Tablet is a combination of Azilsartan and Chlorthalidone. It is used to treat high blood pressure. Azilsartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Together, Macarbi CH Tablet helps treat high blood pressure.

Storage

Keep Macarbi CH Tablet out of the sight and reach of children.

Side effects of Macarbi CH Tablet

High Uric Acid Levels In Blood

High Levels Of Fat In Blood

Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
Avoid foods with label “partially hydrogenated oils”.
Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
Limit consumption of egg yolks.
Exercise for at least 30 minutes 5 days a week.
Aim for weight loss and maintain healthy weight.
Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
Limit alcohol consumption as excessive drinking may raise cholesterol levels.

Sun Allergy

Electrolyte Abnormalities

Inform your doctor if you have an underlying condition, like kidney disease or heart failure, contributing to the imbalance.
Eat a balanced diet with potassium (bananas, spinach), sodium (salt, soy sauce), calcium (dairy, leafy greens), and magnesium (nuts, dark chocolate).
Drink electrolyte-rich beverages like sports drinks (Gatorade, Powerade), coconut water, and fresh vegetable juice.
Stay hydrated throughout the day by drinking lots of water.
Avoid excessive intake of sugary, salty, and unhealthy fatty foods.
If you have a persistent electrolyte imbalance after making dietary and lifestyle modifications, get medical help.

Stiff Muscles

Drink plenty of water throughout the day to prevent dehydration-induced muscle cramps and spasms.
Include magnesium and potassium-rich foods like bananas, leafy greens, almonds, avocados, and sweet potatoes in your diet to help relax muscles.
Perform gentle stretches for affected muscle groups multiple times a day, especially before and after
Engage in activities like swimming, walking, or yoga to maintain muscle flexibility and range of motion.
Stay in a comfortable environment and avoid exposure to excessive heat or cold, which can worsen spasticity.
Apply heat or cold packs to affected areas as needed, depending on your individual response.
Aim for adequate sleep to support muscle recovery.
Adjust your sleeping position to minimize muscle tension.
Practice deep breathing exercises, meditation, or progressive muscle relaxation to manage stress.

Restlessness

Restlessness is related to mental health and needs medical attention if it's severe.
Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
Prevent smoking as it can impact your calmness of body and mind.
Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

Drop In Blood Pressure Upon Standing Up

Do not stand up suddenly. Lie down and get up slowly only when you feel better.
Avoid alcohol and large meals.
Drink enough water before standing for long periods.
Exercise regularly; however, avoid exercising in extreme heat.
Eat small, low-carb meals.
Wear compression stockings.

Drug Warnings

Do not stop taking Macarbi CH Tablet without your doctor's advice. Sudden stopping of Macarbi CH Tablet may cause changes in your blood pressure. Inform your doctor about gout, electrolyte imbalance, dehydration, heart, kidney or liver problems. Consult your doctor before using Macarbi CH Tablet if you are breastfeeding. Avoid taking Macarbi CH Tablet if you are pregnant. Drive or operate machinery only if you are alert, as Macarbi CH Tablet may cause dizziness. Avoid alcohol consumption as it may cause unpleasant side effects. Keep your doctor informed about your health condition and medications to rule out any side effects.

Drug-Drug Interactions

Azilsartan medoxomilAliskiren

Critical

chlorthalidoneCisapride

Critical

Drug-Drug Interactions

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Azilsartan medoxomilAliskiren

Critical

How does the drug interact with Macarbi CH Tablet:
Taking Aliskiren with Macarbi CH Tablet can increase the risk of low blood pressure and high potassium levels in the body.

How to manage the interaction:
Taking Macarbi CH Tablet with Aliskiren is generally avoided as it may lead to an interaction, it can be taken if prescribed by the doctor. Consult the doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Make sure to hydrate while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.

chlorthalidoneCisapride

Critical

How does the drug interact with Macarbi CH Tablet:
Co-administration of Macarbi CH Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Macarbi CH Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.

Azilsartan medoxomilLisinopril

Severe

How does the drug interact with Macarbi CH Tablet:
Co-administration of Macarbi CH Tablet with Lisinopril can increase potassium levels in the blood.

How to manage the interaction:
Although taking Macarbi CH Tablet with Lisinopril can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in your hands and feet, or palpitations. Do not discontinue any medications without consulting a doctor.

Azilsartan medoxomilRamipril

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet with Ramipril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Ramipril together with Macarbi CH Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.

Azilsartan medoxomilPerindopril

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet with Perindopril can cause low blood pressure, kidney function impairment, or increased potassium levels.

How to manage the interaction:
Although taking Macarbi CH Tablet with Perindopril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without consulting a doctor.

Azilsartan medoxomilCaptopril

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet with Captopril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Macarbi CH Tablet with Captopril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.

Azilsartan medoxomilLofexidine

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet and Lofexidine together can increase the risk of side effects.

How to manage the interaction:
Although taking Macarbi CH Tablet and Lofexidine can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Azilsartan medoxomilEnalapril

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet with Enalapril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Macarbi CH Tablet with Enalapril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience symptoms like vomiting, weakness, confusion, tingling in your hands and feet, or palpitations. Do not stop using any medications without talking to a doctor.

Azilsartan medoxomilFosinopril

Severe

How does the drug interact with Macarbi CH Tablet:
Taking Macarbi CH Tablet with Fosinopril can increase the risk of developing low blood pressure, kidney function impairment, or increased potassium levels.

How to manage the interaction:
Although taking Macarbi CH Tablet with Fosinopril together can result in an interaction, it can be taken if a doctor has prescribed it. However, let the doctor know if you experience symptoms like vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.

Azilsartan medoxomilAmiloride

Severe

How does the drug interact with Macarbi CH Tablet:
Co-administration of Macarbi CH Tablet with Amiloride may increase potassium levels in the blood.

How to manage the interaction:
Although taking Amiloride and Macarbi CH Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Do regular physical activity or exercise.
Limit sodium chloride intake (table salt) in your daily diet.
Avoid smoking and alcohol consumption.
Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.
Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils.
A low salt/sodium diet and regular exercise are recommended along with Macarbi CH Tablet for effective results.

Side Effects of Macarbi CH Tablet

Nausea
Taste changes
Stomach upset
Diarrhoea
Headache
Weakness
Dizziness
Decreased blood pressure (hypotension)

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Macarbi CH Tablet work?

Macarbi CH Tablet works by relaxing and widening the blood vessels. It also prevents fluid retention due to excess salt build-up. This helps the heart pump blood easily throughout the body, lowering blood pressure.

Can I take potassium supplements with Macarbi CH Tablet ?

Macarbi CH Tablet can cause high levels of potassium in the blood leading to hyperkalaemia. Hence it is not recommended to use potassium supplements along with Macarbi CH Tablet . However, consult your doctor if you are already taking other medicines before starting Macarbi CH Tablet .

Can I take Macarbi CH Tablet if I am diabetic?

Chlorthalidone in Macarbi CH Tablet may affect blood sugar levels in people with diabetes. Hence, it is advised to regularly monitor your sugar levels while taking Macarbi CH Tablet . Your doctor may adjust the dose accordingly. Please seek medical advice for more information before starting Macarbi CH Tablet .

Do I need to take Macarbi CH Tablet even if my blood pressure becomes normal?

Even though your blood pressure becomes normal after using Macarbi CH Tablet , it may switch back to high ranges if you stop using it. Therefore, continue taking Macarbi CH Tablet for as long as your doctor has advised.

Does Macarbi CH Tablet cause dehydration?

Macarbi CH Tablet may cause dehydration. It is advised to drink plenty of fluids and avoid heavy exercises and sports to prevent dehydration. If you experience extreme thirst and dry mouth for a longer period, please seek medical advice.

Can I take Macarbi CH Tablet with other medicines?

Consult your doctor before taking Macarbi CH Tablet with other medicines as Macarbi CH Tablet may increase the rate of gastrointestinal transit, which may affect the absorption of other orally administered medicines taken simultaneously.

Drug-Drug Interactions Checker List

METOPROLOL
POTASSIUM CHLORIDE
ASPIRIN
CALCIUM CARBONATE
MAGNESIUM HYDROXIDE

Special Advise

Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
Thiazide diuretics like Chlorthalidone may increase serum triglyceride and cholesterol levels. Hence it is advised to monitor your cholesterol levels regularly.
Chlorthalidone in Macarbi CH Tablet may interfere with specific lab tests like parathyroid and protein-bound iodide tests; hence, inform the person doing the tests that you are taking Macarbi CH Tablet .
Your doctor may advise you to get a regular kidney function test and blood examinations for potassium levels and other electrolytes while using Macarbi CH Tablet to rule out any renal impairment.
Regular monitoring of blood glucose levels is advised in diabetic patients while using Macarbi CH Tablet .

Disease/Condition Glossary

Hypertension: Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases and can be caused due to obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing. Blood pressure is measured in the ratio of systolic pressure to diastolic pressure. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. The ideal blood pressure range lies between 90/60 mmHg and 120/80 mmHg. It is considered high blood pressure if the blood pressure is 140/90 mmHg or greater.