MACGEST 100MG CAPSULE

MACGEST 100MG CAPSULE belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, MACGEST 100MG CAPSULE also treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

MACGEST 100MG CAPSULE contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take MACGEST 100MG CAPSULE for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of MACGEST 100MG CAPSULE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, MACGEST 100MG CAPSULE or any other medicines, please tell your doctor. Avoid taking MACGEST 100MG CAPSULE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking MACGEST 100MG CAPSULE if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking MACGEST 100MG CAPSULE to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking MACGEST 100MG CAPSULE. Drive only if you are alert as MACGEST 100MG CAPSULE may cause drowsiness or dizziness.

MACGEST 100MG CAPSULE contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, MACGEST 100MG CAPSULE is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). MACGEST 100MG CAPSULE replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour.

• Dizziness
• Drowsiness
• Headache
• Mood changes
• Diarrhoea
• Vaginal discharge
• Joint pain
• Hot flashes (sudden feeling of warmth) 
• Constipation

If you are allergic to soya, MACGEST 100MG CAPSULE or any other medicines, please tell your doctor. Avoid taking MACGEST 100MG CAPSULE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking MACGEST 100MG CAPSULE if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking MACGEST 100MG CAPSULE to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking MACGEST 100MG CAPSULE. Drive only if you are alert as MACGEST 100MG CAPSULE may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking MACGEST 100MG CAPSULE. If you are about to undergo any surgery, please inform your doctor that you are taking MACGEST 100MG CAPSULE.

Drug-Drug Interaction: MACGEST 100MG CAPSULE may interact with anticonvulsants (carbamazepine, phenytoin, phenobarbital), anti-tuberculosis drugs (rifabutin, rifampicin), anti-HIV drugs (ritonavir, nevirapine, nelfinavir, efavirenz), benzodiazepine (diazepam), water tablet (spironolactone), immunosuppressant (ciclosporin), blood thinners (phenindione), skeletal muscle relaxants (tizanidine), antifungals (terbinafine, ketoconazole, griseofulvin).

Drug- Food Interaction: MACGEST 100MG CAPSULE may interact with St. Jonh’s wort (herbal supplement to treat depression).

Drug-Disease Interaction: Avoid taking MACGEST 100MG CAPSULE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage  (bleeding in the brain). If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking MACGEST 100MG CAPSULE.

• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL
• RIFABUTIN
• RIFAMPICIN
• RITONAVIR
• NEVIRAPINE
• NELFINAVIR
• EFAVIRENZ
• DIAZEPAM
• SPIRONOLACTONE
• CICLOSPORIN
• PHENINDIONE
• TIZANIDINE
• TERBINAFINE
• KETOCONAZOLE
• GRISEOFULVIN

• Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
• Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
• Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
• Try to be stress-free to improve your mood swings due to hormonal fluctuations.
• Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).