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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Composition :

PROGESTERONE-300MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macgest SR 300 Tablet

Macgest SR 300 Tablet belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, Macgest SR 300 Tablet also treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Macgest SR 300 Tablet contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Macgest SR 300 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Macgest SR 300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Macgest SR 300 Tablet or any other medicines, please tell your doctor. Avoid taking Macgest SR 300 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Macgest SR 300 Tablet if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Macgest SR 300 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Macgest SR 300 Tablet . Drive only if you are alert as Macgest SR 300 Tablet may cause drowsiness or dizziness.

Uses of Macgest SR 300 Tablet

Female infertility, Female hormonal imbalance

Directions for Use

Take Macgest SR 300 Tablet as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take Macgest SR 300 Tablet at bedtime as it may cause dizziness or drowsiness.

Medicinal Benefits

Macgest SR 300 Tablet contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Macgest SR 300 Tablet is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Macgest SR 300 Tablet replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour.

Storage

Store in a cool and dry place away from sunlight
Side effects of Macgest SR 300 Tablet
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Drug Warnings

If you are allergic to soya, Macgest SR 300 Tablet or any other medicines, please tell your doctor. Avoid taking Macgest SR 300 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Macgest SR 300 Tablet if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Macgest SR 300 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Macgest SR 300 Tablet . Drive only if you are alert as Macgest SR 300 Tablet may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Macgest SR 300 Tablet . If you are about to undergo any surgery, please inform your doctor that you are taking Macgest SR 300 Tablet .

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
ProgesteroneVenetoclax
Severe

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Macgest SR 300 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Macgest SR 300 Tablet contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Macgest SR 300 Tablet may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Macgest SR 300 Tablet and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Macgest SR 300 Tablet reduces this risk.

You are recommended to inform your doctor that you are taking Macgest SR 300 Tablet as you may need to stop taking Macgest SR 300 Tablet 4 to 6 weeks before surgery to decrease the risk of blood clot.

Macgest SR 300 Tablet may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

Macgest SR 300 Tablet is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Macgest SR 300 Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • RITONAVIR
  • NEVIRAPINE
  • NELFINAVIR
  • EFAVIRENZ
  • DIAZEPAM
  • SPIRONOLACTONE
  • CICLOSPORIN
  • PHENINDIONE
  • TIZANIDINE
  • TERBINAFINE
  • KETOCONAZOLE
  • GRISEOFULVIN

Special Advise

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Disease/Condition Glossary

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

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