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  3. Macorate CR 500 Tablet 10's

Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
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Composition :

VALPROIC ACID-500MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macorate Cr 500Mg Tablet

Macorate Cr 500Mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Macorate Cr 500Mg Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Macorate Cr 500Mg Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Macorate Cr 500Mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Macorate Cr 500Mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Macorate Cr 500Mg Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Macorate Cr 500Mg Tablet. If you are pregnant, do not take Macorate Cr 500Mg Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Macorate Cr 500Mg Tablet. If you are breastfeeding, inform your doctor before taking Macorate Cr 500Mg Tablet. As Macorate Cr 500Mg Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Macorate Cr 500Mg Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Macorate Cr 500Mg Tablet

Epilepsy (fits), Bipolar disorder, Migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Macorate Cr 500Mg Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Macorate Cr 500Mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Macorate Cr 500Mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Keep Macorate Cr 500Mg Tablet out of the sight and reach of children.
Side effects of Macorate CR 500 Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

Drug Warnings

Before taking the Macorate Cr 500Mg Tablet, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Macorate Cr 500Mg Tablet. Consult your doctor immediately if you become pregnant while receiving a Macorate Cr 500Mg Tablet. Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Macorate Cr 500Mg Tablet.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Side Effects of Macorate Cr 500Mg Tablet

  • Stomach pain
  • Feeling or being sick
  • Diarrhoea
  • Dry or sore mouth or swollen gums
  • Shakes (tremors) in a part of your body
  • Unusual eye movements
  • Feeling tired or sleepy
  • Headache
  • Weight gain
  • Thinning hair, or changes to the colour or texture of your hair
  • Irregular or delayed periods

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Macorate Cr 500Mg Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Macorate Cr 500Mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Macorate Cr 500Mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Macorate Cr 500Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Macorate Cr 500Mg Tablet. Avoid getting pregnant while taking Macorate Cr 500Mg Tablet as it could lead to serious birth defects. Do not stop taking Macorate Cr 500Mg Tablet and consult your doctor immediately if you become pregnant.

Macorate Cr 500Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • WARFARIN
  • ASPIRIN
  • CIMETIDINE
  • RITONAVIR
  • ERYTHROMYCIN
  • VENLAFAXINE
  • QUETIAPINE
  • CHOLESTYRAMINE
  • MEFLOQUINE
  • CHLOROQUINE

Special Advise

  • Blood and urine tests may be affected by the Macorate Cr 500Mg Tablet. Inform the person conducting the exams that you will be taking Macorate Cr 500Mg Tablet.
  • If you are of childbearing age, utilise effective contraception continuously during your treatment with Macorate Cr 500Mg Tablet.
  • Contact your doctor immediately if you become pregnant while taking Macorate Cr 500Mg Tablet.

Disease/Condition Glossary

Epilepsy: It is a sudden rush of electricity in the brain. It is a nervous system disorder that occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle cramps and spasms. More substantial seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.

Migraine: Migraine is a neurological condition that is characterized by intense headaches. A migraine is usually a moderate or severe headache felt as a throbbing pain on one side of the head.

Have a query?

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Alcohol

Caution

Do not consume alcohol while taking Macorate Cr 500Mg Tablet as alcohol can worsen the side effects of the Macorate Cr 500Mg Tablet, including sleepiness and dizziness.

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Pregnancy

Unsafe

Macorate Cr 500Mg Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Macorate Cr 500Mg Tablet.

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Breast Feeding

Caution

Macorate Cr 500Mg Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Macorate Cr 500Mg Tablet. Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Caution

Macorate Cr 500Mg Tablet may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Macorate Cr 500Mg Tablet.

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Liver

Caution

Inform your doctor before receiving the Macorate Cr 500Mg Tablet if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Macorate Cr 500Mg Tablet.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

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