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MACOX 300MG TABLET

MACOX 300MG TABLET

Consult Doctor
Not for online sale
Prescription drug
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Composition

RIFAMPICIN-300MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About MACOX 300MG TABLET

MACOX 300MG TABLET belongs to the group of medicines called macrolide antibiotics, primarily used in combination with other medicines to treat tuberculosis (TB). Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It is also used to treat other bacterial infections. MACOX 300MG TABLET does not work against infections caused by the virus, including cold and flu. As MACOX 300MG TABLET is an antibiotic, it does not work against infections caused by the virus, including cold and flu. The bacteria causing tuberculosis (TB) are highly contagious that spread from one person to another via tiny droplets released into the air (through coughs or sneezes).

MACOX 300MG TABLET consists of a drug called 'rifampicin' which works by inactivating a bacterial protein enzyme (RNA-polymerase) and inhibits bacterial cell death.  MACOX 300MG TABLET acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis). 

MACOX 300MG TABLET should be taken as recommended by your doctor. It should be taken 30 minutes before food or 2 hours after food on an empty stomach. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Most of these side effects are mild and subside over time. However, if any of these effects persist contact your doctor immediately.

MACOX 300MG TABLET may raise liver enzymes like ALT and can cause jaundice if taken longer. Hence, a regular liver function test (LFT) is recommended while taking treatment with MACOX 300MG TABLET. Maintain a gap of one hour between MACOX 300MG TABLET and antacid medicines. MACOX 300MG TABLET is not recommended if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking MACOX 300MG TABLET as it passes into breast milk. MACOX 300MG TABLET may cause dizziness, and vision problems; hence avoid driving vehicles or operating machines that require mental concentration. Avoid alcohol consumption while taking MACOX 300MG TABLET as it could lead to increased drowsiness, dizziness, and liver damage.

Uses of MACOX 300MG TABLET

Tuberculosis (TB)

Medicinal Benefits

MACOX 300MG TABLET contains 'Rifampicin' that treats Tuberculosis (TB) by inactivating a bacterial genetic material that allows TB bacteria to make a copy of its protein for further growth inside the host cell (human). MACOX 300MG TABLET is active against gram-positive cocci bacteria like Mycobacteria, Clostridium difficle and gram-negative bacteria like Neisseria meningitides, N. gonorrhoeae and Hemophilus influenzae. MACOX 300MG TABLET is also used as a second-line treatment in the treatment of cholestatic pruritus. It also treats leprosy, severe gram-positive bacterial infections (like osteomyelitis, endocarditis, brain abscess, meningitis and implant infections) in combinations with other antibiotics. 

Directions for Use

Tablet/Capsule: Take MACOX 300MG TABLET 30 minutes before or 2 hours after food on an empty stomach. Swallow MACOX 300MG TABLET as a whole; do not crush or chew the tablet/capsule. The dose and duration of MACOX 300MG TABLET can vary depending on your condition and the severity of the infection.Dispersible tablet (DT): Before taking this, take a glass of water and disperse the tablet in it and then drink it.Suspension: Shake the bottle well. It can be taken 30 minutes before or 2 hours after food on an empty stomach. The dose and duration of MACOX 300MG TABLET can vary depending upon your condition and severity of the infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MACOX 300MG TABLET

  • Drowsiness
  • Dizziness 
  • Headache 
  • Weakness
  • Muscle pain
  • Heartburn 
  • Diarrhoea 
  • Gas 
  • Numbness or tingling sensation 

Drug Warnings

MACOX 300MG TABLET should be avoided if you are allergic to any of its contents. Inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems on priority before starting treatment with MACOX 300MG TABLET. Avoid foods and drinks containing histamines or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while treating with MACOX 300MG TABLET as they might cause interaction. Maintain a gap of one hour between MACOX 300MG TABLET and antacid medicines.

MACOX 300MG TABLET is not recommended for pregnant women. Hence, inform your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while using MACOX 300MG TABLET as it passes into breast milk. MACOX 300MG TABLET should be given to children only if prescribed by the paediatrician. MACOX 300MG TABLET may cause dizziness or drowsiness, so avoid driving vehicles. Avoid alcohol consumption along with MACOX 300MG TABLET as it could lead to increased drowsiness, dizziness and liver damage.

Drug Interactions

DRUG-DRUG INTERACTIONS: MACOX 300MG TABLET may have interaction with pain killers (acetaminophen, hydrocodone), anti-TB (ethambutol, pyrazinamide) and vitamins (ergocalciferol, cholecalciferol, ascorbic acid), blood thinners (warfarin), Antacids (Pantoprazole, omeprazole), Antibiotics (doxycycline, ciprofloxacin, amoxicillin), cough syrups (diphenhydramine), anti-seizure drugs  ( phenytoin, phenobarbital, Iamotrigine),  azole antifungals (itraconazole, ketoconazole, voriconazole), calcium channel blockers (diltiazem, nimodipine, verapamil).

FOOD-DRUG INTERACTIONS: Do not consume alcohol while taking MACOX 300MG TABLET as it could lead to increased dizziness and liver damage. Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking MACOX 300MG TABLET as they might cause interaction.

DRUG-DISEASE INTERACTION: MACOX 300MG TABLET may have interactions with colitis (inflammation in the lining of the colon),  porphyria ( blood disease), hemodialysis, liver toxicity, and kidney and liver dysfunction.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • HYDROCODONE
  • ERGOCALCIFEROL
  • ASCORBIC ACID
  • CHOLECALCIFEROL
  • WARFARIN
  • PANTOPRAZOLE
  • DOXYCYCLINE
  • CIPROFLOXACIN
  • AMOXICILLIN
  • DIPHENHYDRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try to take foods rich in vitamin C such as orange, kiwi, broccoli, and bell pepper which helps in improving the immune system. 
  • Avoid consuming processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • Smoking and alcohol consumption should be avoided as it causes dizziness.
  • Drinking pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

Special Advise

  • MACOX 300MG TABLET may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
  • MACOX 300MG TABLET may cause temporary discolouration of urine, tears, and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discoloured. Contact your doctor for further advice.
  • Regular liver tests may be advised by your doctor while taking MACOX 300MG TABLET to check how your liver is functioning.
  • MACOX 300MG TABLET may affect test results of some blood tests such as folate, vitamin B12, and liver function tests. Hence inform your doctor or the lab person if any such tests are advised.

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

Country of origin

INDIA

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0036

FAQs

Do not stop taking MACOX 300MG TABLET despite symptomatic relief. To treat your condition effectually, continue taking MACOX 300MG TABLET for as long as it has been prescribed by doctor and must be taken strictly at proper times.
MACOX 300MG TABLET is a bactericidal drug that means it kills bacteria. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for bacterial survival, thereby killing the bacteria.
MACOX 300MG TABLET has no known serious drug interaction with ibuprofen or aspirin. Inform your doctor about all the medication you are currently taking to avoid harmful interactions that may reduce treatment effectiveness.
Yes, in some cases headache can be caused as a side effect of MACOX 300MG TABLET. A patient must consult a doctor if it progresses with time.
MACOX 300MG TABLET is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with MACOX 300MG TABLET. Please consult your doctor if you have any liver problems before taking MACOX 300MG TABLET as it may worsen the situation. However, prolonged use of MACOX 300MG TABLET can cause raised ALT (liver enzyme), and the person taking the treatment can developed jaundice symptoms like yellowing of eye, skin etc. In this case, stop taking MACOX 300MG TABLET and immediately contact a doctor.
MACOX 300MG TABLET may cause temporary discoloration of urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Contact your doctor for further advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

MACOX 300MG TABLET intake is not recommended with alcohol. A patient is not advised to take alcohol with MACOX 300MG TABLET as it may increase chances of liver damage.

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Pregnancy

Unsafe

Not recommended during pregnancy. Tell your doctor if you are pregnant or planning to become pregnant. MACOX 300MG TABLET should not be taken during pregnancy as it can affect your unborn baby's growth and may cause complications to the mother and baby after birth.

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Breast Feeding

Unsafe

Not recommended while breastfeeding. A patient should not breast-feed while taking MACOX 300MG TABLET. This is because a small amount of MACOX 300MG TABLET may pass into the mother’s milk. So, if you are breastfeeding or planning to breast-feed, talk to your doctor.

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Driving

Caution

Caution should be maintained by a patient while driving a motor vehicle or doing hazardous work. A patient may experience dizziness, have problems with vision or have other side effects that could affect his ability to drive after taking this medicine. If this happens, do not drive.

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Liver

Caution

Not recommended to be taken in liver patients without doctors consultation as MACOX 300MG TABLET has been found to affect liver function with raised ALT enzymes.

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Kidney

Caution

Not recommended for kidney patients without doctor's consultation. Intake of MACOX 300MG TABLET in these people may result in symptoms like blood in the urine, a change in the amount of urine passed and feeling drowsy or weak.

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Children

Safe if prescribed

MACOX 300MG TABLET is safe to be prescribed in children below 12 years. Dose adjustments by the doctor are done according to age, weight, and severity of infection