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Not for online sale
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macox Plus Tablet

Macox Plus Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.
 
Macox Plus Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Macox Plus Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).
 
In some cases, Macox Plus Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Let your doctor know if your child is allergic to any of the components in Macox Plus Tablet. Keep your doctor informed about your child's health condition and medications to rule out any side effects/interactions.

Uses of Macox Plus Tablet

Tuberculosis.

Directions for Use

Macox Plus Tablet should be given on an empty stomach, i.e., one hour prior or two hours after meals.Liquid: Administer the prescribed dose using a measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Medicinal Benefits

Macox Plus Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Macox Plus Tablet contains two anti-mycobacterial agents, Rifampicin and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Macox Plus Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Macox Plus Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Loss of appetite

Drug Warnings

Do not give Macox Plus Tablet to the child if he/she is allergic to any of the components in Macox Plus Tablet, if he/she has acute liver disease, drug-induced liver disease, if the child has experienced liver damage linked to rifampicin or isoniazid, or if the child is taking anti-fungal (voriconazole) or medicines for HIV infection (protease inhibitors). Macox Plus Tablet may cause liver damage; consult your doctor if the child experiences symptoms such as unexplained loss of appetite, nausea, vomiting, jaundice, dark urine, persistent fatigue for more than 3 days, abdominal pain and tenderness. Consult a doctor if your child gets flu-like symptoms such as headache, fever, or muscle ache. Inform the doctor if your child has HIV infection, epilepsy, psychiatric disorder, diabetes, porphyria, phenylketonuria (metabolic disorder), peripheral neuropathy (tingling sensation in hands and feet), kidney or liver problems, if your child is allergic to ethionamide or niacin (nicotinic acid), or if your child is taking cortisone or any cortisone-like drug. 

Drug-Drug Interactions

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RifampicinSaquinavir
Critical
RifampicinPirfenidone
Critical

Drug-Drug Interactions

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RifampicinSaquinavir
Critical
How does the drug interact with Macox Plus Tablet:
Taking saquinavir with Macox Plus Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Macox Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with Macox Plus Tablet:
Taking pirfenidone with Macox Plus Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Macox Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinRanolazine
Critical
How does the drug interact with Macox Plus Tablet:
When ranolazine is taken with Macox Plus Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Macox Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinIndinavir
Critical
How does the drug interact with Macox Plus Tablet:
When Indinavir is taken with Macox Plus Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Macox Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with Macox Plus Tablet:
Taking darunavir with Macox Plus Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Macox Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with Macox Plus Tablet:
Taking Voriconazole with Macox Plus Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Macox Plus Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Macox Plus Tablet:
When Lovastatin is taken with Macox Plus Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Macox Plus Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Macox Plus Tablet:
When Lomitapide is taken with Macox Plus Tablet, Macox Plus Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Macox Plus Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidRegorafenib
Critical
How does the drug interact with Macox Plus Tablet:
When Macox Plus Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Macox Plus Tablet is not recommended, it taken can be taken if prescribed by the doctor.
RifampicinApixaban
Severe
How does the drug interact with Macox Plus Tablet:
Taking apixaban with Macox Plus Tablet can decrease the blood levels of apixaban, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between apixaban and Macox Plus Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Macox Plus Tablet Substitute

Substitutes safety advice
  • RCINEX R CIN + INH 450MG CAPSULE

    by Others

    12.33per tablet
  • Akt-2 Tablet 10's

    by Others

    12.38per tablet
  • MYCOCOX TABLET

    by Others

    6.84per tablet
  • RINIZIDE FORTE DT TABLET

    by Others

    5.63per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Macox Plus Tablet works by killing Mycobacterium tuberculosis which causes TB (tuberculosis).

Macox Plus Tablet may cause reddish-orange discolouration of body fluids such as tears, sputum and urine; this is not harmful and does not require medical attention. However, consult your doctor if you have any concerns.

Macox Plus Tablet might stain soft contact lenses. The child should use spectacles and avoid wearing contact lens while taking Macox Plus Tablet.

Drug-Drug Interactions Checker List

  • VORICONAZOLE
  • SAQUINAVIR
  • RITONAVIR
  • DISULFIRAM

Disease/Condition Glossary

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight.

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