MACPRIL H 2.5MG TABLET belongs to a class of medication called 'anti-hypertensive agents' prescribed alone or in combination with other drugs to lower the raised blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

MACPRIL H 2.5MG TABLET contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and therefore helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing heart attack or stroke chances. 

You can take MACPRIL H 2.5MG TABLET with a meal or after/before a meal. Your doctor will advise you on the exact dosage and how often you have to take MACPRIL H 2.5MG TABLET based on your medical condition. Sometimes, you may experience headaches, tiredness, slow heart rate, and nausea. Most of these side effects of MACPRIL H 2.5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. MACPRIL H 2.5MG TABLET may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery.

Try not to stop taking this medicine of your own. You should not stop using the MACPRIL H 2.5MG TABLET even if your blood pressure becomes normal. Doing so may worsen your condition. Tell your doctor if you have had or currently have liver, kidney, or heart problems. MACPRIL H 2.5MG TABLET is not recommended in pregnancy and lactation. You should regularly monitor your blood pressure and heart rate. Please tell your doctor if you are taking any other medicines or are allergic to MACPRIL H 2.5MG TABLET. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

MACPRIL H 2.5MG TABLET contains Ramipril and hydrochlorothiazide. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and therefore helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing the chances of heart attack or stroke. However, MACPRIL H 2.5MG TABLET does not cure high blood pressure (hypertension) but does help control it. In addition to this, MACPRIL H 2.5MG TABLET also reduces the physical effects of anxiety.

• Feeling dizzy or lightheaded
• Headache
• Diarrhoea
• Being sick
• Mild skin rash
• Blurred vision
• Hypotension
• Nausea (feeling sick)

MACPRIL H 2.5MG TABLET should not be given to the people allergic to MACPRIL H 2.5MG TABLET, have low blood pressure (less than 90 mm of Hg), have had a heart attack, diabetes, kidney disease, liver disease, are pregnant women, or planning to get pregnant and breastfeeding women. MACPRIL H 2.5MG TABLET may alter your blood sugar level, so tell your doctor about this before using MACPRIL H 2.5MG TABLET. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), and aortic stenosis (heart valve problem). MACPRIL H 2.5MG TABLET can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take MACPRIL H 2.5MG TABLET and breastfeeding. Do not consume alcohol with MACPRIL H 2.5MG TABLET as it may increase the risk of low blood pressure. Avoid potassium supplements with MACPRIL H 2.5MG TABLET as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking MACPRIL H 2.5MG TABLET. Drink a lot of fluids as MACPRIL H 2.5MG TABLET can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.

Drug-Drug Interactions: MACPRIL H 2.5MG TABLET may interact with other diuretics, blood pressure-lowering drugs (aliskiren, metoprolol, sacubitril, sacuatorvastatin), anti-epilepsy medicines (carbamazepine, phenobarbital), anti-depression medicines (lithium), immune-suppressing drugs (cyclosporine), anti-diabetic drugs (metformin) and painkillers (ibuprofen, aspirin), anti-gout drugs (allopurinol), pain killers (diclofenac, ibuprofen), potassium supplements, birth control pills (drospirenone),  immune system affecting drugs (everolimus, sirolimus) etc. If you are taking any of the above, speak with your doctor.

Drug-Food Interactions: You are recommended not to consume alcohol along with MACPRIL H 2.5MG TABLET to avoid unpleasant side effects.

Drug-Disease Interactions: MACPRIL H 2.5MG TABLET should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, or heart failure, gout, sensitive skin to sunlight, low serum potassium (hypokalemia), patients with nil urine output (anuria), etc.

• ATORVASTATIN
• METOPROLOL
• CARBAMAZEPINE
• PHENOBARBITAL
• LITHIUM
• METFORMIN
• DICLOFENAC
• ALLOPURINOL
• ASPIRIN
• TACROLIMUS
• DROSPIRENONE+ETHINYLESTRADIOL
• DIAZOXIDE
• PRAZOSIN

• Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, then only one serving for women and two servings is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.
• Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.
• Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

• Diagnostic tests like complete blood count (CBC), blood sodium and potassium levels, kidney function, and liver function should be closely monitored while taking treatment with MACPRIL H 2.5MG TABLET to check for side effects and treatment progress.

Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. High blood pressure (hypertension) can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked), brain damage (stroke), and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.