Macsita 50 Tab 10'S
₹82.8*
MRP ₹92
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₹78*
MRP ₹92
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Macsita 50 Tab 10'S belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in treating type 2 diabetes in adults. Macsita 50 Tab 10'S is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
Macsita 50 Tab 10'S contains sitagliptin. Macsita 50 Tab 10'S work by blocking the action of DPP-4 (an enzyme which destroys the hormone 'Incretin'). The enzyme 'Incretins' helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed.
Macsita 50 Tab 10'S should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Macsita 50 Tab 10'S is hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of the nose and throat with common cold) and headache.
Macsita 50 Tab 10'S should not be used in patients with type 1 diabetes and for treating diabetic ketoacidosis. Macsita 50 Tab 10'S should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Macsita 50 Tab 10'S abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Macsita 50 Tab 10'S should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeed. Prolonged intake of Macsita 50 Tab 10'S may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Macsita 50 Tab 10'S is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Macsita 50 Tab 10'S. Severe allergic reactions might occur in some patients taking Macsita 50 Tab 10'S like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Macsita 50 Tab 10'S in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Macsita 50 Tab 10'S should be closely monitored as severe drug interaction has been observed.
Macsita 50 Tab 10'S work by blocking the action of DPP-4 (an enzyme which destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed. Thus, Macsita 50 Tab 10'S plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
Tell your doctor before consuming Macsita 50 Tab 10'S if you have allergic reactions to sitagliptin, any medications, foods, or any components present in Macsita 50 Tab 10'S. Prolonged intake of Macsita 50 Tab 10'S may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Macsita 50 Tab 10'S is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Macsita 50 Tab 10'S. Severe allergic reactions might occur in some patients taking Macsita 50 Tab 10'S like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Macsita 50 Tab 10'S in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Macsita 50 Tab 10'S should be closely monitored as severe drug interaction has been observed.
Drug-Drug Interactions: Macsita 50 Tab 10'S interacts with anti-depressant medications (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine). Other drug interactions can contribute to increased low blood sugar, including sex hormones (androgens), anti-oxidant (alpha-lipoic acid), painkillers (aspirin), anti-TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.
Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Macsita 50 Tab 10'S.
Drug-Disease Interactions: Macsita 50 Tab 10'S should be used with caution in patients with a history of pancreatitis/pancreatic disease and renal dysfunction.
Type 2 diabetes is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, weight gain may occur, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also include neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increased chance of heart attack or stroke.
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Alcohol
Caution
No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.
Pregnancy
Caution
Macsita 50 Tab 10'S is not suggested during pregnancy since there is insufficient evidence on how it may impact a growing infant.
Breast Feeding
Unsafe
Consult your doctor; there is no substantial research yet on using Macsita 50 Tab 10'S in breastfeeding/nursing mothers. Macsita 50 Tab 10'S should be used in breastfeeding mothers only if the benefits outweigh the risks.
Driving
Caution
Macsita 50 Tab 10'S should not impair your ability to drive, or operate machinery or tools if your blood sugar levels are stable. When your blood sugar levels drop too low, your concentration suffers. If this occurs, refrain from driving or using equipment or tools until you feel better.
Liver
Caution
In rare cases, liver enzyme elevations have been reported in the prolonged usage of Macsita 50 Tab 10'S. So, if you have or have a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.
Kidney
Unsafe
Acute renal failure has been reported in the patients taking Macsita 50 Tab 10'S. In severe cases, it sometimes requires dialysis. Hence, dosage adjustment can be recommended in patients with moderate or severe kidney disease and patients with kidney failure (ESRD - end-stage renal dialysis).
Children
Unsafe
The safety and efficacy of Macsita 50 Tab 10'S in children have not been established.
Product Substitutes
Recommended for a 30-day course: 3