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Written By ,
Reviewed By Sureshvarma D , MPharma

About Madopar 250 Tablet 10's

Madopar 250 Tablet 10's belongs to the class of medications called ‘Antiparkinson agents’ used to treat Parkinson’s disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion. It causes stiffness, shaking, difficulty in walking, coordination, and balance. These symptoms interfere with daily activities and decrease the quality-of-life.

Madopar 250 Tablet 10's contains Levodopa and Benserazide. Levodopa is a dopamine agonist and acts by increasing the dopamine levels in the brain. Dopamine is a chemical messenger present in the brain that is important for movement control. Benserazide is a decarboxylase inhibitor. It prevents the breakdown of levodopa and increases its effectiveness. Together, Madopar 250 Tablet 10's can effectively reduce the symptoms of Parkinson’s disease.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Madopar 250 Tablet 10's are Involuntary jerking movements of the body, agitation, hallucinations (seeing or hearing things that are not true), nausea, vomiting, loss of appetite, weight gain, constipation, skin rash, itching, confusion, tiredness, water retention, and difficulty sleeping or sudden onset of sleep episodes. These side-effects are usually seen at the initial days of therapy. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Madopar 250 Tablet 10's if you are allergic to any contents of it. Do not take Madopar 250 Tablet 10's if you have glaucoma (increased pressure in the eye), serious liver, kidney, or heart problems, overactive thyroid, severe mental illness, skin cancer, and have been using non-selective monoamine oxidase inhibitor’ (MAOI) in the last 14 days. It is not recommended for use in individuals less than 25 years of age, pregnant women, and breastfeeding mothers. It should be used with caution in the elderly, as dose adjustments may be necessary. Do not consume alcohol as it may increase the risk of side-effects. Madopar 250 Tablet 10's may affect your ability to drive, so do not drive or operate heavy machinery if you are not fully alert.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Abbott Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Madopar 250 Tablet 10's

Parkinson’s disease.

Medicinal Benefits

Madopar 250 Tablet 10's is used in the treatment of Parkinson’s disease. It replaces the deficient dopamine in the brain, which is essential for the brain's normal functioning. It helps to improve muscle control, thereby allowing the body to have more normal movements. It reduces the symptoms of Parkinson’s disease, thereby improving the quality-of-life.

Side Effects of Madopar 250 Tablet 10's

  • Involuntary jerking movements of the body
  • Agitation
  • Hallucinations (seeing or hearing things that are not true)
  • Nausea
  • Vomiting
  • Loss of appetite
  • Diarrhea
  • Irregular heartbeat (faster or slower than normal)
  • Weight gain
  • Constipation
  • Skin rash
  • Itching
  • Confusion
  • Tiredness
  • Water retention
  • Anaemia (low numbers of red blood cells)
  • Changes to how things taste or a loss of taste
  • Difficulty sleeping or sudden onset of sleep episodes

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Madopar 250 Tablet 10's, inform your doctor if you have hormonal problems, diabetes, heart problems, stomach ulcer, and osteomalacia (soft and weak bones). Do not take this medicine if you have been taking non-selective monoamine oxidase inhibitors (MAOI) such as isocarboxazid and phenelzine in the last 14 days. If you notice impulse control disorders such as gambling addiction, increased libido (sexual desire), sexual addiction, compulsive spending or buying, and binge eating, inform your doctor immediately. In such cases, the doctor may reduce the dose or stop the treatment based on your condition.

Therapeutic Class

ANTIPARKINSON AGENTS

Drug-Drug Interactions

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LevodopaProcarbazine
Critical
LevodopaTranylcypromine
Critical

Drug-Drug Interactions

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LevodopaProcarbazine
Critical
How does the drug interact with Madopar 250 Tablet 10's:
Using Madopar 250 Tablet 10's together with procarbazine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Procarbazine with Madopar 250 Tablet 10's together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaTranylcypromine
Critical
How does the drug interact with Madopar 250 Tablet 10's:
Taking Tranylcypromine with Madopar 250 Tablet 10's can increase the risk of high blood pressure

How to manage the interaction:
Taking Madopar 250 Tablet 10's with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaPhenelzine
Critical
How does the drug interact with Madopar 250 Tablet 10's:
Using Madopar 250 Tablet 10's together with phenelzine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Madopar 250 Tablet 10's with Phenelzine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaLinezolid
Severe
How does the drug interact with Madopar 250 Tablet 10's:
Using Madopar 250 Tablet 10's together with linezolid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between linezolid and Madopar 250 Tablet 10's, you can take these medicines together if prescribed by a doctor. However, if you experience a sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, you should seek immediate medical attention. Do not stop using any medications without talking to a doctor.
LevodopaEsketamine
Severe
How does the drug interact with Madopar 250 Tablet 10's:
Coadministration of Madopar 250 Tablet 10's with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Madopar 250 Tablet 10's and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sleepiness, confusion, difficulty concentrating, and impairment in thinking, judgment consult your doctor immediately. Do not stop using any medications without a doctor's advice.
LevodopaAmisulpride
Severe
How does the drug interact with Madopar 250 Tablet 10's:
Coadministration of Madopar 250 Tablet 10's with amisulpride may increase the risk and severity of side effects and also reduce the effectiveness of both drugs.

How to manage the interaction:
Although taking amisulpride and Madopar 250 Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience drowsiness, low blood pressure, dizziness, and lightheadedness. Do not discontinue any medications without consulting a doctor.
LevodopaIsocarboxazid
Severe
How does the drug interact with Madopar 250 Tablet 10's:
Using Madopar 250 Tablet 10's together with isocarboxazid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Isocarboxazid with Madopar 250 Tablet 10's together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor right away if you experience symptoms like severe headache, confusion, chest pain, or sudden weakness. Do not stop using any medications without a doctor's advice.
LevodopaGlycopyrronium bromide
Severe
How does the drug interact with Madopar 250 Tablet 10's:
Coadministration of Madopar 250 Tablet 10's with glycopyrronium bromide can significantly decrease the blood levels of Madopar 250 Tablet 10's.

How to manage the interaction:
Although using glycopyrronium bromide and Madopar 250 Tablet 10's together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMANTADINE
  • SELEGILINE
  • ROPINIROLE
  • ENTACAPONE
  • FERROUS SULPHATE
  • METOCLOPRAMIDE
  • CHLORPROMAZINE
  • PROMAZINE
  • PROCHLORPERAZINE
  • HALOPERIDOL
  • FLUPENTIXOL
  • ZUCLOPENTHIXOL
  • DIAZEPAM
  • TETRABENAZINE
  • PAPAVERINE
  • RESERPINE
  • EPINEPHRINE
  • NOREPINEPHRINE
  • ISOPROTERENOL
  • AMPHETAMINE
  • CODEINE
  • MORPHINE
  • DOMPERIDONE
  • Orphenadrine
  • Pergolide

Diet & Lifestyle Advise

  • Avoid high protein foods like soy protein, fish, eggs, chicken, beef, and pork. Eat more whole-grain foods such as whole-wheat bread, oatmeal, brown rice, or pasta.
  • Eat more fiber-rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Special Advise

  • Do not discontinue treatment abruptly without discussing it with your doctor, as Madopar 250 Tablet 10's may cause withdrawal symptoms such as confusion, muscle stiffness, and changes in heartbeat and breathing.
  • Let your doctor know that you are taking Madopar 250 Tablet 10's before undergoing any laboratory tests as it may affect some test results. In addition, it needs to be stopped before undergoing surgery or before taking a general anesthetic.
  • Use reliable and effective contraception while using this medicine to prevent pregnancy.

Disease/Condition Glossary

Parkinson’s disease (PD): It is also known as a movement disorder that mainly affects a person's ability to perform regular activities. It is a chronic (long-term) and progressive disorder that can worsen with time if proper treatment is not provided at the right time. Some of the common symptoms faced by many persons include tremors at rest, stiffness of the limbs, slowness of movement, difficulty in movement or walking, and impaired balance. Other motor symptoms include trouble in solving problems, small handwriting, stooped posture, etc. This disease also affects the brain's ability to work properly, such as sleep disturbances, reduced ability to smell, depression, fatigue, and anxiety. However, the symptoms of this disease vary from person to person. There are certain neurons present in the brain that are responsible for making dopamine. This neurotransmitter helps to regulate the movement of the body. Loss of dopamine is supposed to be the primary reason for the occurrence of Parkinson's disease. Treatment with medicines and physiotherapy may help control the symptoms and provide a quality life for as long as possible.

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