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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Not for online sale
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mahagaba-Nt 75 Tab

Mahagaba-Nt 75 Tab is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.

Mahagaba-Nt 75 Tab is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Mahagaba-Nt 75 Tab helps to treat neuropathic pain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Mahagaba-Nt 75 Tab may cause drowsiness and dizziness, so drive only if you are alert. Mahagaba-Nt 75 Tab should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mahagaba-Nt 75 Tab as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Mahagaba-Nt 75 Tab

Neuropathic pain

Directions for Use

Take Mahagaba-Nt 75 Tab with or without food. Swallow Mahagaba-Nt 75 Tab as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Mahagaba-Nt 75 Tab is a combination of two medicines, namely: Pregabalin and Nortriptyline. Mahagaba-Nt 75 Tab is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, Mahagaba-Nt 75 Tab helps to treat neuropathic pain (pain due to nerve damage).

Storage

Keep Mahagaba-Nt 75 Tab out of reach and sight of children.

Drug Warnings

Do not take Mahagaba-Nt 75 Tab if you are allergic to any of its contents. Inform your doctor before taking Mahagaba-Nt 75 Tab if you have or had heart problems, bipolar syndrome, severe liver disease or if you have taken MAO inhibitors in the last 14 days. Consult your doctor before taking cough-cold medicines containing adrenaline-like drugs such as ephedrine, phenylpropanolamine, isoprenaline, noradrenaline or phenylephrine. Consult your doctor if you are pregnant or breastfeeding. Mahagaba-Nt 75 Tab may cause drowsiness and dizziness, so drive only if you are alert. Mahagaba-Nt 75 Tab should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mahagaba-Nt 75 Tab as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Mahagaba-NT 75 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Mahagaba-NT 75 Tablet:
Taking Ketamine with Mahagaba-NT 75 Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Mahagaba-NT 75 Tablet and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinEsketamine
Severe
How does the drug interact with Mahagaba-NT 75 Tablet:
When Mahagaba-NT 75 Tablet and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Mahagaba-NT 75 Tablet and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Sodium oxybate together with Mahagaba-NT 75 Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Mahagaba-NT 75 Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Mahagaba-NT 75 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Mahagaba-NT 75 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Mahagaba-NT 75 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Tapentadol together with Mahagaba-NT 75 Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Mahagaba-NT 75 Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Mahagaba-NT 75 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinMethadone
Severe
How does the drug interact with Mahagaba-NT 75 Tablet:
Using Mahagaba-NT 75 Tablet together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Mahagaba-NT 75 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Side Effects of Mahagaba-Nt 75 Tab

  • Dizziness
  • Sleepiness
  • Nausea
  • Blurred vision
  • Peripheral oedema (swelling of lower legs and hands)
  • Weight gain
  • Dry mouth

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mahagaba-Nt 75 Tab contains Pregabalin and Nortriptyline. Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Mahagaba-Nt 75 Tab helps to treat neuropathic pain.

Mahagaba-Nt 75 Tab may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Mahagaba-Nt 75 Tab . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

To treat your condition effectually, continue taking Mahagaba-Nt 75 Tab for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mahagaba-Nt 75 Tab .

Mahagaba-Nt 75 Tab is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Mahagaba-Nt 75 Tab may cause peripheral oedema. Peripheral oedema is the swelling of hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • MIRTAZAPINE
  • FLUOXETINE
  • SERTRALINE
  • CITALOPRAM
  • ESCITALOPRAM
  • BUPROPION
  • CODEINE
  • FENTANYL
  • HYDROCODONE
  • MORPHINE
  • ACETAMINOPHEN
  • TRAMADOL
  • OXYCODONE
  • GABAPENTIN
  • PHENOBARBITAL
  • PHENYTOIN
  • CLONAZEPAM
  • TOPIRAMATE
  • DIAZEPAM
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • ONDANSETRON

Special Advise

  • Mahagaba-Nt 75 Tab contains Nortriptyline which may cause suicidal thoughts. People taking Mahagaba-Nt 75 Tab should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease, infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mahagaba-Nt 75 Tab as it may cause increased drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Mahagaba-Nt 75 Tab ; your doctor will decide whether Mahagaba-Nt 75 Tab can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Mahagaba-Nt 75 Tab may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Mahagaba-Nt 75 Tab should not be given to children as safety and efficacy have not been established.

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