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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Zeelab Pharmacy Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Malepril-H Tablet

Malepril-H Tablet belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Malepril-H Tablet is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take Malepril-H Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of Malepril-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Malepril-H Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Malepril-H Tablet. Avoid potassium supplements with Malepril-H Tablet as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Malepril-H Tablet.

Uses of Malepril-H Tablet

Hypertension (high blood pressure)

Directions for Use

Take Malepril-H Tablet with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Malepril-H Tablet is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Malepril-H Tablet or any other medicines, please tell your doctor. Malepril-H Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Malepril-H Tablet. It is advised to complete the full course of medication and do not suddenly stop taking Malepril-H Tablet as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with Malepril-H Tablet as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking Malepril-H Tablet. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Malepril-H Tablet. 

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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FAQs

Malepril-H Tablet contains Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

You are not recommended to take furosemide with Malepril-H Tablet as co-administration of these two medicines may increase the risk of low blood pressure. However, if you experience dizziness, reduced heart rate, headache or fainting, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

It is advised to inform your doctor if you have had skin cancer or develop an unexpected skin lesion as hydrochlorothiazide in Malepril-H Tablet may increase the risk of certain types of skin and lip cancer especially when taken in high doses for a long period. Therefore, it is recommended to protect the skin from UV rays and sun exposure while taking Malepril-H Tablet.

No, you are not recommended to take potassium supplements with Malepril-H Tablet as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines with Malepril-H Tablet.

If you have any kidney problems, it is advised to inform your doctor before taking Malepril-H Tablet as Malepril-H Tablet may worsen kidney functioning if there is any existing kidney problem. However, if you experience unexplained weight gain, swelling in feet, ankles or hands, please consult your doctor immediately.

You are not recommended to take more than the prescribed dose of Malepril-H Tablet as it may cause Malepril-H Tablet overdose resulting in symptoms such as low blood pressure, cough, nausea, dizziness, cramps, drowsiness, fast or slow heartbeat, anxiety, increased urination or difficulty in urination. However, if you experience any of these symptoms while taking Malepril-H Tablet, please consult a doctor immediately.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • PREGABALIN
  • METOPROLOL
  • AMLODIPINE
  • ALBUTEROL
  • SALMETEROL
  • CHOLECALCIFEROL

Special Advise

  • Regular monitoring of blood pressure, kidney functioning, and amount of electrolytes such as sodium, potassium, magnesium, creatinine, and liver enzyme levels are recommended while taking Malepril-H Tablet.
  • If you are about to take an anti-doping test, please inform your doctor that you are taking Malepril-H Tablet as it may give a positive result.
  • Low salt diet and regular exercise are recommended along with Malepril-H Tablet for effective results.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. 

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