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Written By Urvashi Bharti , MBBS
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

BISOPROLOL-2.50MG

Manufacturer/Marketer :

CMG Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Manobis-2.5Mg Tablet

Manobis-2.5Mg Tablet belongs to the group of antihypertensive medications used to treat hypertension (high blood pressure) and angina pectoris. Hypertension is a medical condition in which the blood exerts high blood pressure against the walls of the arteries (blood vessels). This increases the heart's workload, and if it continues for a long time, the heart and arteries may not function properly.

Manobis-2.5Mg Tablet contains Bisoprolol, which affects the body's response to some nerve impulses, particularly in the heart. As a result, Manobis-2.5Mg Tablet slows down the heart rate and makes it easier for the heart to pump blood around the body. Thereby, Manobis-2.5Mg Tablet helps lower the raised blood pressure and reduces the risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Manobis-2.5Mg Tablet should be taken as directed by the physician. The dose and duration will be based on your medical condition and response to the treatment. Manobis-2.5Mg Tablet can cause side effects like tiredness, weakness, nausea, vomiting, diarrhoea, or constipation. Most of these side effects of Manobis-2.5Mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are pregnant or breastfeeding, you should avoid taking Manobis-2.5Mg Tablet. Manobis-2.5Mg Tablet may cause tiredness, drowsiness, or dizziness, so do not operate vehicles or machines if you have any of these symptoms. Manobis-2.5Mg Tablet is not recommended in children. Before taking Manobis-2.5Mg Tablet, inform your doctor about your medical history and all medications you are currently taking to rule out any potential side effects and interactions.

Uses of Manobis-2.5Mg Tablet

Hypertension and angina pectoris.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Manobis-2.5Mg Tablet is an antihypertensive medication used to treat hypertension/high blood pressure and angina pectoris. Manobis-2.5Mg Tablet alters how the body responds to certain nerve impulses, particularly in the heart. As a result, Manobis-2.5Mg Tablet reduces the heart rate and makes it easier for the heart to circulate blood throughout the body. Thereby, Manobis-2.5Mg Tablet aids in reducing the high blood pressure and the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Manobis-2.5Mg Tablet

  • Tiredness
  • Weakness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Dizziness
  • Headache
  • Feeling of coldness or numbness in hands or feet
  • Low blood pressure

Drug Warnings

If you are pregnant or breastfeeding, you should avoid taking Manobis-2.5Mg Tablet. If you are allergic to Bisoprolol or any other ingredients in this medicine, do not take it. Manobis-2.5Mg Tablet is not recommended for people who have severe asthma or chronic lung disease, as well as those who have a slow or irregular heart rate, very low blood pressure, severe blood circulation problems, heart failure, cardiogenic shock, metabolic acidosis (excess acid in the blood), untreated phaeochromocytoma, and a rare adrenal gland tumour (medulla). Manobis-2.5Mg Tablet may cause tiredness, drowsiness, or dizziness. Do not operate vehicles or machines if you have any of these symptoms. Manobis-2.5Mg Tablet is not recommended for children. Before taking Manobis-2.5Mg Tablet, inform your doctor about your medical history and all medications you are currently taking to rule out any potential side effects and interactions.

Drug-Drug Interactions

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BisoprololDolasetron
Severe
BisoprololLofexidine
Severe

Drug-Drug Interactions

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BisoprololDolasetron
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet with Dolasetron may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with Dolasetron if prescribed by the doctor. Consult the prescriber if you experience sudden dizziness, fainting, lightheadedness, or irregular heartbeat. Do not discontinue the medication without consulting a doctor.
BisoprololLofexidine
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet with Lofexidine may have effects in lowering blood pressure.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with Lofexidine if prescribed by the doctor. Consult the prescriber if you develop headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not discontinue the medication without consulting a doctor.
BisoprololAminophylline
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Aminophylline with Manobis-2.5Mg Tablet could reduce the metabolism of Aminophylline which increased the levels and enhance the effects of Aminophylline.

How to manage the interaction:
Taking aminophylline and Manobis-2.5Mg Tablet together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
BisoprololDisopyramide
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet with Disopyramide may increase the effects of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the prescriber if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
BisoprololTizanidine
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet and Tizanidine may increase the risk of low blood pressure.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with Tizanidine if prescribed by the doctor. If you experience headache, dizziness, lightheadedness, or palpitations. Do not discontinue the medication without consulting a doctor.
BisoprololAtenolol
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
When Manobis-2.5Mg Tablet is combined with Atenolol the severity or risk of side effects may be increased.

How to manage the interaction:
Although there may be an interaction, atenolol can be taken with Manobis-2.5Mg Tablet if prescribed by the doctor. Consult the prescriber if you experience any unusual side effects. Do not discontinue the medication without consulting a doctor.
BisoprololSaquinavir
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet with Saquinavir may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with Saquinavir if prescribed by the doctor. Consult the prescriber if you develop dizziness, lightheadedness, fainting, or slow or irregular heart rate. Do not discontinue the medication without consulting a doctor.
BisoprololGlimepiride
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Concomitant use of Manobis-2.5Mg Tablet with glimepiride may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with glimepiride if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
BisoprololPropranolol
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Manobis-2.5Mg Tablet with Propranolol may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there may be an interaction, Manobis-2.5Mg Tablet can be taken with propranolol if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BisoprololPotassium gluconate
Severe
How does the drug interact with Manobis-2.5Mg Tablet:
Co-administration of Potassium gluconate may increase the hyperkalemic (high potassium levels in the blood) activities of Manobis-2.5Mg Tablet.

How to manage the interaction:
Although there may be an interaction, Potassium gluconate can be taken with Manobis-2.5Mg Tablet if prescribed by the doctor. Consult the prescriber if you develop symptoms of hyperkalemia (high potassium) such as muscle weakness, numbness, shortness of breath, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit consumption of excess sodium and sugary drinks.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Make a habit of regular exercising for at least 1-2 hours a day, or at least one should walk for about half an hour for good health.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Try to include heart-healthy omega-3 fatty acids-containing food in your daily diet. 
  • Limiting salt intake and including high fhigh-fiber in the diet is best.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Manobis-2.5Mg Tablet Substitute

Substitutes safety advice
  • Bisobis 2.5 Tablet 10's

    by Others

    4.77per tablet
  • Bisomeg 2.5mg Tablet 10's

    by AYUR

    3.60per tablet
  • Bisoryl-2.5 Tablet 10's

    by Others

    6.00per tablet

Author Details

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Drug-Diseases Interactions

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BISOPROLOL-2.50MGOther cardiac arrhythmias
Severe
BISOPROLOL-2.50MGHypotension
Severe

Drug-Diseases Interactions

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BISOPROLOL-2.50MGOther cardiac arrhythmias
Severe
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet is contraindicated in patients with diagnosis of sinus bradyarrhythmia and heart block

How to manage the interaction:
The use of Manobis-2.5Mg Tablet is contraindicated in patients with sinus bradyarrhythmia (abnormally slow heart rate) or heart block greater than the first degree (unless a functioning pacemaker is present).
BISOPROLOL-2.50MGHypotension
Severe
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet is contraindicated in patients who have hypotension or cardiogenic shock.

How to manage the interaction:
The use of this medicine is contraindicated in patients with low blood pressure or cardiogenic shock.
BISOPROLOL-2.50MGChronic kidney disease
Severe
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet SHOULD BE USED CAUTIOUSLY IN RENAL DISEASE PATIENTS

How to manage the interaction:
Patients with kidney disease may be at greater risk for adverse effects from Manobis-2.5Mg Tablet due to decreased drug clearance. Dose adjustment may be needed.
BISOPROLOL-2.50MGDependence on enabling machines and devices, not elsewhere classified
Severe
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet SHOULD BE ADMINISTERED CAUTIOUSLY IN PATIENTS REQUIRING HEMODIALYSIS

How to manage the interaction:
Manobis-2.5Mg Tablet should be used with caution in patients with hemodialysis.
BISOPROLOL-2.50MGAbnormalities of heart beat
Severe
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet IS CONTRAINDICATED IN PATIENTS WITH SINUS BRADYARRHYTHMIA

How to manage the interaction:
The use of this medicine is contraindicated in patients with sinus bradyarrhythmia (abnormally slow heart rate) or heart block greater than the first degree (unless a functioning pacemaker is present).
BISOPROLOL-2.50MGGlaucoma
Moderate
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet SHOULD BE USED CAUTIOUSLY IN THE GLAUCOMA PATIENTS

How to manage the interaction:
Manobis-2.5Mg Tablet may lower intraocular pressure. Therefore, dose adjustment may be needed in patients with glaucoma or intraocular hypertension.
BISOPROLOL-2.50MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Manobis-2.5Mg Tablet:
Manobis-2.5Mg Tablet SHOULD BE USED CAUTIOUSLY IN MYASTHENIA GRAVIS PATIENTS

How to manage the interaction:
Manobis-2.5Mg Tablet should be used cautiously in patients with myasthenia gravis as it may potentiate muscle weakness with certain myasthenic symptoms such as double vision, drooping eyes, and generalized weakness.

FAQs

Yes, Manobis-2.5Mg Tablet can be taken in the morning or at any other time. Take your first dose before bedtime as it can make you feel dizzy. If you don't feel dizzy after taking the first dose, take Manobis-2.5Mg Tablet in the morning. It is better to take it at a fixed time.

Usually, Manobis-2.5Mg Tablet is prescribed for a long-term treatment ranging from weeks to months for treating heart-related conditions. However, taking it on your own for a year without a doctor's consent can be fatal. Hence, only take it as long as your doctor prescribes it.

No, you are not recommended to stop taking Manobis-2.5Mg Tablet without consulting your doctor as it may cause blood pressure rise and this may increase your risk of heart attack and stroke. Therefore, take Manobis-2.5Mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Manobis-2.5Mg Tablet, please consult your doctor so that the dose may be gradually reduced.

No, you are not recommended to consume alcohol with Manobis-2.5Mg Tablet as it may increase the risk of side effects like dizziness, tiredness, and sleepy.

No, Manobis-2.5Mg Tablet is not safe to be taken in pregnancy. It can have many harmful effects on the newborn and can even cause complications in pregnancy. The use of Manobis-2.5Mg Tablet may decrease the blood supply to the fetus, slow down its growth, cause intrauterine death, abortion, or early labour. Therefore, it is advised to consult your doctor if you are planning a baby or if you become pregnant during the course of treatment with this medication.

Drug-Drug Interactions Checker List

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  • IMIPRAMINE
  • AMITRIPTYLINE
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  • DICLOFENAC
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  • MEFLOQUINE
  • ADRENALINE
  • DOBUTAMINE
  • NORADRENALINE
  • RIFAMPICIN

Special Advise

  • Regularly monitor blood pressure levels to prevent hypotension (low blood pressure).
  • Get up slowly while rising from a lying or sitting position as Manobis-2.5Mg Tablet may cause dizziness.
  • Do not skip any doses or stop taking Manobis-2.5Mg Tablet without consulting your doctor. Quitting Manobis-2.5Mg Tablet on your own may raise the blood pressure and increase heart attack chances.

Disease/Condition Glossary

Hypertension: Hypertension is a chronic medical condition when blood pressure is too high. Blood pressure is the measurement of the force that the heart uses to pump blood to all body parts. When the heart pumps more blood, the arteries become narrower, and blood pressure becomes high. If the blood pressure becomes uncontrolled, it may cause serious heart diseases like brain damage (stroke), heart attacks, and kidney failure.

Angina pectoris: It is a kind of chest pain caused due to decreased blood flow to the heart, which means insufficient oxygen supply to the heart muscle. The chest pain is often triggered by emotional stress or physical activity. Angina is a symptom of coronary artery disease. The symptoms of angina include dizziness, shortness of breath, nausea, tiredness, anxiety or excessive sweating. The risk factors for angina include smoking, diabetes, overweight, high blood pressure, high cholesterol, not exercising, or a history of heart disease.

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