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  1. Home
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  3. Materna CC 50mg Tablet

Materna CC 50mg Tablet, Pack of 1 Tablet
Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

CLOMIPHENE-50MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Materna CC 50mg Tablet

Materna CC 50mg Tablet belongs to the group of medications called ‘ovulation stimulants’ used to treat infertility in women who are not ovulating (producing an egg) properly or have irregular or no menstrual cycle. The problem with ovulation is a common cause of infertility in women.

Materna CC 50mg Tablet contains ‘clomiphene’ which belongs to the class of ‘ovulation stimulants’. It is used to induce ovulation (egg production) in a woman who has problems with ovulation and wishes to get pregnant. This medicine works by stimulating the production of hormones that are responsible for the ovulation process.  

You should take this medicine as prescribed by your doctor. The common side-effects of Materna CC 50mg Tablet are flushing (reddening of the skin, especially face), vasomotor symptoms (night sweats and hot flushes), abdominal bloating or discomfort, nausea (feeling sick), vomiting (being sick), headache, vision problems and breast pain. Tell your doctor if any of these side-effects persist or get worsen.

Do not take Materna CC 50mg Tablet if you are allergic to clomiphene or any other ingredients present in it, develop any allergic symptoms such as a rash, swallowing or breathing problems, swelling of your lips, face, throat, or tongue, previously diagnosed with liver disease, unexplained and unusual menstrual bleeding, have a type of cancer that gets worse by hormones, or have an ovarian cyst.  It is not recommended to use in pregnant women. So, it is advised to take a pregnancy test before using this medicine. It is also not recommended for use in children, adolescents, men and post-menopausal women. Inform your doctor if you are breastfeeding as this medicine may affect the amount of breast milk produced. Inform your doctor if you are taking any other prescription, non-prescription medicines or herbal products before taking this medicine.

Uses of Materna CC 50mg Tablet

Female infertility.

Directions for Use

Swallow it as a whole with a glass of water. Do not break, chew, or crush it.

Medicinal Benefits

Materna CC 50mg Tablet is used for fertility enhancement in women who are experiencing infertility due to problems with ovulation (production and release of an egg from the ovary). It works by stimulating the hormones that are necessary for the ovulation process.

Storage

Store in a cool and dry place away from sunlight
Side effects of Materna CC 50mg Tablet
  • Schedule a comprehensive medical evaluation with a specialized women's health expert.
  • Adhere to a personalized medication regimen to alleviate symptoms and promote ovarian health.
  • Embrace a holistic approach to wellness, incorporating nutritious eating habits and consistent physical activity.
  • Refrain from engaging in physically demanding tasks that may exacerbate discomfort.
  • Prioritize rejuvenation and relaxation, ensuring adequate sleep and downtime.
  • Explore complementary therapies, like acupuncture or botanical supplements, under the guidance of a qualified medical professional.
  • Inform your doctor about the hot flushes you're experiencing to assess whether the medication is causing the issue.
  • Your doctor may prescribe alternative medications or adjust your current dosage to minimize hot flushes.
  • To help alleviate symptoms, maintain a balanced diet rich in whole foods, fruits, vegetables, and omega-3 fatty acids.
  • To help reduce hot flashes, incorporate lifestyle changes such as regular exercise, stress management techniques, and adequate sleep.
  • Stay hydrated by drinking plenty of water and avoiding caffeine and alcohol.
  • Use fans or air conditioners to keep your environment cool and avoid triggers like spicy foods and hot beverages.
  • Consider incorporating foods and herbs that may help alleviate hot flushes, such as soy, flaxseeds, and black cohosh, into your diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.

Drug Warnings

Before taking Materna CC 50mg Tablet, inform your doctor if you are having an early menopause, diagnosed as infertile, stopped menstrual periods due to underweight, previously diagnosed with fits or seizures (fits), uterine fibroids (non-cancerous tumors in the womb), polycystic ovaries (presence of small cysts on the enlarged ovaries), swollen ovaries, or hypertriglyceridemia (increased fat levels in the body) or a family history of hypertriglyceridemia. Your doctor may also check for other causes of infertility before prescribing this medicine. Materna CC 50mg Tablet contains lactose and sucrose, so inform your doctor if you have any intolerance to sugars.

Drug-Drug Interactions

verifiedApollotooltip
clomipheneOspemifene
Critical
clomipheneFluoroestradiol (18f)
Severe

Drug-Drug Interactions

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clomipheneOspemifene
Critical
How does the drug interact with Materna CC 50mg Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.

How to manage the interaction:
Taking Materna CC 50mg Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Materna CC 50mg Tablet:
Co-administration of Fluoroestradiol F 18 together with Materna CC 50mg Tablet may reduce the action of Fluoroestradiol F 18.

How to manage the interaction:
Taking Materna CC 50mg Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
clomipheneBexarotene
Severe
How does the drug interact with Materna CC 50mg Tablet:
Co-administration of Materna CC 50mg Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.

How to manage the interaction:
Although there is an interaction, Materna CC 50mg Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume a healthy diet that is rich in fibre and proteins and low in carbohydrates and fats. 
  • Avoid processed or high-sugar foods. 
  • Stay active and shed excess weight if you are overweight or obese. Do not perform intense exercises as they may negatively impact your reproductive health. Increase the intensity of exercise gradually.
  • Being underweight may also reduce your chances of getting pregnant. So, prepare a diet chart that can help you to gain weight healthily. 
  • Avoid stress as it may decrease your chances of getting pregnant. Try relaxation techniques and receive support and counselling if necessary. 
  • Limit alcohol and caffeine intake. Quit smoking.

Habit Forming

No

Therapeutic Class

GYNECOLOGY RELATED DRUGS

Materna CC 50mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
CLOMIPHENE-50MGOther abnormal uterine and vaginal bleeding
Severe
CLOMIPHENE-50MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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CLOMIPHENE-50MGOther abnormal uterine and vaginal bleeding
Severe
How does the disease interact with Materna CC 50mg Tablet:
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Materna CC 50mg Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.

How to manage the interaction:
The use of Materna CC 50mg Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIPHENE-50MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Materna CC 50mg Tablet:
Hepatic dysfunction: Materna CC 50mg Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Materna CC 50mg Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Materna CC 50mg Tablet.

How to manage the interaction:
The use of Materna CC 50mg Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIPHENE-50MGDisorders of endocrine glands in diseases classified elsewhere
Severe
How does the disease interact with Materna CC 50mg Tablet:
Pituitary activity: Materna CC 50mg Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Materna CC 50mg Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.

How to manage the interaction:
Materna CC 50mg Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIPHENE-50MGOther disorders of adrenal gland
Severe
How does the disease interact with Materna CC 50mg Tablet:
Uncontrolled adrenal dysfunction : Materna CC 50mg Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Materna CC 50mg Tablet therapy may cause changes in steroid production and/or fluid balance.

How to manage the interaction:
The use of Materna CC 50mg Tablet is contraindicated in patients with uncontrolled adrenal function.
CLOMIPHENE-50MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with Materna CC 50mg Tablet:
Hyperlipidemia: Some patients who are on Materna CC 50mg Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Materna CC 50mg Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Materna CC 50mg Tablet.

How to manage the interaction:
Hypertriglyceridemia may occur during Materna CC 50mg Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Materna CC 50mg Tablet therapy.

FAQs

Materna CC 50mg Tablet contains 'clomiphene' which can induce ovulation in women who have problems with fertility. It enhances fertility by stimulating the production of hormones that are necessary for ovulation.

Materna CC 50mg Tablet is not a cure to infertility. It can only enhance your chance of getting pregnant by inducing ovulation. In most of the cases, the women ovulate within 7 to 10 days after taking this medicine. So, ask your doctor if you have any questions regarding the benefits of Materna CC 50mg Tablet.

Materna CC 50mg Tablet is given to women who cannot become pregnant due to problems with ovulation. It is not recommended for children, adolescents, men, pregnant women and post-menopausal women.

Materna CC 50mg Tablet can be taken with or without food. However, take this medicine at the same time every day for effective results.

After taking Materna CC 50mg Tablet, this medicine may (1) induce ovulation, and you may get your period, or (2) induce ovulation, and you get pregnant and not have a period, or (3) fail to induce ovulation. So, if you have not had your period, take a pregnancy test at home or in the doctor's office to confirm pregnancy.

Materna CC 50mg Tablet can only enhance your chances of fertility. The reason for not getting pregnant after taking this medicine may be low dosage, other underlying causes of infertility, or any comorbid conditions that interfere with Materna CC 50mg Tablet action. Consult your doctor to know the exact reason.

Drug-Drug Interactions Checker List

  • BEXAROTENE

Special Advise

Materna CC 50mg Tablet may cause multiple pregnancies (pregnant with more than one child at the same time) or ectopic pregnancy (growing of fetus outside the womb). These conditions may also occur if you are not taking this medicine. However, discuss with your doctor the possible risks before taking Materna CC 50mg Tablet. 

Disease/Condition Glossary

Female Infertility: A woman is said to have fertility problems when she cannot become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is also included in infertility. The most common cause of infertility is the problem with ovulation or damage to the uterus.

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