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  3. Matilonaz-MD 0.5 Tablet 10's

Matilonaz-MD 0.5 Tablet 10's, Pack of 10 TABLETS
Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Composition :

CLONAZEPAM-0.5MG

Manufacturer/Marketer :

Matias Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Matilonaz-MD 0.5 Tablet 10's

Matilonaz-MD 0.5 Tablet 10's belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Matilonaz-MD 0.5 Tablet 10's may also be used to treat restless leg syndrome. Epilepsy is a common neurological disorder that produces recurrent seizures. Seizures occur due to a sudden burst of electrical activity in the brain that disrupts its normal functioning. Panic disorder is an anxiety disorder characterised by frequent episodes of panic or fear.

Matilonaz-MD 0.5 Tablet 10's contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, Matilonaz-MD 0.5 Tablet 10's aids in the treatment of seizures, panic disorder, and involuntary muscle spasms.

Your doctor will advise you on how often you need to take this medicine based on your medical condition. In some cases, Matilonaz-MD 0.5 Tablet 10's may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Most of these side effects do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Matilonaz-MD 0.5 Tablet 10's is a habit-forming drug. Therefore, before stopping this medicine, consult your doctor as it may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. If you are pregnant or breastfeeding, consult your doctor before taking Matilonaz-MD 0.5 Tablet 10's. Avoid drinking alcohol while taking Matilonaz-MD 0.5 Tablet 10's as it may cause increased dizziness and drowsiness. It is recommended not to drive or operate any machinery as Matilonaz-MD 0.5 Tablet 10's may cause dizziness, drowsiness, and problems with walking and coordination.

Uses of Matilonaz-MD 0.5 Tablet 10's

Seizures, Panic disorder, Involuntary muscle spasms, Restless leg syndrome

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Solution: Shake the bottle well before use. Check the label for directions and take it in dose as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.Orally disintegrating strip/Orally disintegrating tablet: Keep the strip/tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip/tablet with wet hands.

Medicinal Benefits

Matilonaz-MD 0.5 Tablet 10's belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Matilonaz-MD 0.5 Tablet 10's may also be used to treat restless leg syndrome. Matilonaz-MD 0.5 Tablet 10's contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. It decreases the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation. Matilonaz-MD 0.5 Tablet 10's benefits people who struggle with anxiety and worries in daily life. Regular intake of the prescribed dose of Matilonaz-MD 0.5 Tablet 10's improves social life and the ability and performance at work, and general wellbeing.

Storage

Store in a cool and dry place away from sunlight
Side effects of Matilonaz-MD 0.5 Tablet
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Muscle weakness can be due to tiredness, which can be managed by eating often.
  • Observe your movements and understand why the muscle is weakening.
  • Regularly do strengthening exercises to improve blood flow throughout the body and reduce weakness.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet, quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.

Drug Warnings

Do not take Matilonaz-MD 0.5 Tablet 10's if you are allergic to clonazepam or any benzodiazepine class of drugs (diazepam, chlordiazepoxide, bromazepam, or flurazepam). Inform your doctor if you have lung disease, glaucoma, muscle weakness (myasthenia gravis), sleep apnoea (difficulty in sleeping), depression, mood problems, suicidal behaviour/thoughts, liver or kidney problems. Taking Matilonaz-MD 0.5 Tablet 10's with opioid medicines can cause severe drowsiness, breathing problems, coma, and death. Matilonaz-MD 0.5 Tablet 10's should be taken with extreme caution in patients with a history of alcohol or drug abuse. Do not stop taking Matilonaz-MD 0.5 Tablet 10's suddenly as it may cause withdrawal symptoms.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamCodeine
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Taking Matilonaz-MD 0.5 Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Matilonaz-MD 0.5 Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Matilonaz-MD 0.5 Tablet with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Matilonaz-MD 0.5 Tablet with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
ClonazepamMorphine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Using Morphine together with Matilonaz-MD 0.5 Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Matilonaz-MD 0.5 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClonazepamHydromorphone
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Matilonaz-MD 0.5 Tablet with Hydromorphone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Matilonaz-MD 0.5 Tablet with Hydromorphone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
ClonazepamEsketamine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Matilonaz-MD 0.5 Tablet with Esketamine may increase side effects.

How to manage the interaction:
Although there is a possible interaction, Matilonaz-MD 0.5 Tablet can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you experience side effects such as confusion, drowsiness, difficulty concentrating, and impairment in judgment, thinking, reaction speed, and motor coordination. Do not discontinue the medication without a doctor's advice.
ClonazepamButorphanol
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Butorphanol with Matilonaz-MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Matilonaz-MD 0.5 Tablet and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamKetamine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
When Matilonaz-MD 0.5 Tablet and Ketamine are taken together, may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Matilonaz-MD 0.5 Tablet, but it can be taken if prescribed by a doctor. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamDezocine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Matilonaz-MD 0.5 Tablet with Dezocine may increase the risk or severity of respiratory distress.

How to manage the interaction:
Although there is a possible interaction between Matilonaz-MD 0.5 Tablet and Dezocine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamSufentanil
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Sufentanil with Matilonaz-MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Matilonaz-MD 0.5 Tablet with Sufentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ClonazepamPentazocine
Severe
How does the drug interact with Matilonaz-MD 0.5 Tablet:
Co-administration of Pentazocine with Matilonaz-MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Matilonaz-MD 0.5 Tablet with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise, which can help lower anxiety by releasing endorphins and improving your sleep and self-image.
  • Find humor in your daily life. Try to watch light-hearted shows to help relieve stress.
  • You can increase your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • Herbs like turmeric, ginger, and chamomile contain anti-inflammatory properties. Including this stuff in meals can reduce inflammation caused due to anxiety disorder.
  • Reduce alcohol, caffeine, added sugar, high salt, and high fat intake. Especially trans-fat may also help reduce inflammation.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower the risk of anxiety.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Matilonaz-MD 0.5 Tablet 10's Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:28 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
CLONAZEPAM-0.5MGGlaucoma
Severe
CLONAZEPAM-0.5MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe

Drug-Diseases Interactions

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CLONAZEPAM-0.5MGGlaucoma
Severe
How does the disease interact with Matilonaz-MD 0.5 Tablet:
Benzodiazepines should not be used by people who have open-angle glaucoma or acute angle-closure glaucoma. While these drugs have very rarely being associated with increased intraocular pressure, they do not have anticholinergic effect.

How to manage the interaction:
Matilonaz-MD 0.5 Tablet is contraindicated in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
CLONAZEPAM-0.5MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe
How does the disease interact with Matilonaz-MD 0.5 Tablet:
Benzodiazepines have the potential to cause abuse and dependency. Particularly during extended usage and/or high dosages, tolerance as well as physical and psychological dependency might form.

How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. If dependency is suspected, withdrawal of benzodiazepine therapy should be done by gradual dose reduction.
CLONAZEPAM-0.5MGAbnormalities of breathing
Severe
How does the disease interact with Matilonaz-MD 0.5 Tablet:
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea. However, some individuals, such as the elderly, the very ill, those who are impaired or taking other CNS depressants, as well as those who have a limited ventilatory reserve, chronic pulmonary insufficiency, or other respiratory diseases, may be susceptible even at regularly prescribed dosages. In these individuals, benzodiazepine therapy should be used with caution.

How to manage the interaction:
When given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in patients including elderly, debilitated or severely ill patients, those receiving other CNS depressants, those with limited ventilatory reserve, chronic pulmonary insufficiency or other respiratory disorders.
CLONAZEPAM-0.5MGEpilepsy
Severe
How does the disease interact with Matilonaz-MD 0.5 Tablet:
The use of benzodiazepines for patients with seizure disorders may increase the frequency of generalised tonic-clonic seizures (grand mal) or accelerate the onset of them. The dosage of an appropriate anticonvulsant drug may need to be raised. Particularly after lengthy usage and/or high dosages, abruptly stopping benzodiazepine medication can cause seizures and other withdrawal symptoms. Patients with a history of seizures who discontinue benzodiazepine medication suddenly may experience status epilepticus.

How to manage the interaction:
Benzodiazepines in patients with seizure disorders may increase the incidence of fits. Dose adjustment or appropriate anticonvulsant medication might need to be initiated. Do not discontinue medication without first consulting with the physician.
CLONAZEPAM-0.5MGPoisoning by diuretics and other and unspecified drugs, medicaments and biological substances
Severe
How does the disease interact with Matilonaz-MD 0.5 Tablet:
Benzodiazepines in paediatric and psychiatric patients with aggressive hyperactivity problems. During benzodiazepine medication for such individuals, it is important to keep monitoring out for any indications of paradoxical stimulation.

How to manage the interaction:
Use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.
CLONAZEPAM-0.5MGDepressive episode
Moderate
How does the disease interact with Matilonaz-MD 0.5 Tablet:
The central nervous system is depressed by benzodiazepines, which can also result in or aggravate mental depression as well as suicidal behaviour and ideas. Patients who were being treated for depression with some of these medications have also reported experiencing episodes of mania and hypomania. In individuals with a history of depression or other mental illnesses, the use of benzodiazepines should be provided with caution. Patients should be watched for any changes in attitude or behaviour. It could be wise to hold off on giving these people a lot of medicine.

How to manage the interaction:
Benzodiazepines may cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with benzodiazepines should be administered cautiously in patients with a history of depression or other psychiatric disorders. Monitoring is advised in patients for any changes in mood or behavior.

FAQs

Matilonaz-MD 0.5 Tablet 10's boosts gamma-aminobutyric acid levels (GABA) in the brain, which helps to ease anxiety, stop seizures (fits), and relax tense muscles.

Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness, or age-related health issues, which may require caution and an adjustment in the dose. Consult a doctor if you have any concerns.

Matilonaz-MD 0.5 Tablet 10's is a controlled and habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if Matilonaz-MD 0.5 Tablet 10's is prescribed for more than 2-4 weeks, your doctor may reduce your dose gradually before completely stopping it to avoid withdrawal symptoms.

Do not stop taking Matilonaz-MD 0.5 Tablet 10's until instructed by your doctor. Stopping Matilonaz-MD 0.5 Tablet 10's may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. Your doctor may lower the dose gradually to prevent this.

Caffeine is a stimulant that may reduce the calming effects of Matilonaz-MD 0.5 Tablet 10's. So, it is advisable to avoid consuming caffeinated beverages like coffee, tea, cola, or chocolate containing caffeine.

Drug-Drug Interactions Checker List

  • ALFENTANIL
  • BUPRENORPHINE
  • CODEINE
  • HYDROMORPHONE
  • DROPERIDOL
  • OLANZAPINE
  • KETAMINE
  • SODIUM OXYBATE
  • ENALAPRIL
  • AMLODIPINE
  • FELODIPINE
  • INDAPAMIDE
  • CIMETIDINE
  • RIFAMPICIN
  • FLUCONAZOLE
  • DIAZEPAM
  • LORAZEPAM

Special Advise

  • Matilonaz-MD 0.5 Tablet 10's can cause dependance and abuse. Therefore, take Matilonaz-MD 0.5 Tablet 10's only in prescribed doses and as directed by your doctor. Do not self-medicate.
  • Matilonaz-MD 0.5 Tablet 10's may cause suicidal thoughts. Consult your doctor immediately if you notice suicidal behaviour.

Disease/Condition Glossary

Seizures: Fits/Seizure is a sudden rush of electrical activity in the brain. It is of two types: Generalized seizure (affects the entire brain) and Partial seizures (affects one part of the brain). A mild seizure might be difficult to recognize as it lasts for only a few seconds, during which one lacks awareness. Stronger seizures cause uncontrollable muscle twitches and spasms, lasting for a few seconds to several minutes. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol, and skipping meals/overeating are a few of the most common triggers for seizures.

Panic disorder: Panic disorder is an anxiety disorder characterised by frequent episodes of panic or dread. At times, everyone feels sensations of anxiety and panic. It is a natural reaction to stressful or potentially harmful conditions. However, someone suffering from panic disorder experiences worries, stress, and panic on a regular basis and at any moment, frequently for no apparent cause.

Involuntary muscle spasm: When the nerve impulses that control muscle movements are damaged or interrupted, it could lead to muscle spasms. The sudden involuntary contractions of the muscle can be painful and uncomfortable. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in movement, and pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms.

Restless leg syndrome: Restless leg syndrome, also known as Willis-Ekbom illness, is a common nervous system disorder characterised by an intense, irresistible urge to move the legs. The primary symptom of restless leg syndrome is a strong need to move the legs. It can also induce a creeping or crawling sensation in the feet, calves, and thighs. The sensation is frequently exacerbated in the evening or at night. The arms are occasionally affected as well.

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