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Not for online sale
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Matiz Plus Tablet

Matiz Plus Tablet belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.

Matiz Plus Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. 

Take Matiz Plus Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Matiz Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may confuse them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Uses of Matiz Plus Tablet

Irritable bowel syndrome (IBS), Painful stomach cramps

Directions for Use

Take Matiz Plus Tablet on an empty stomach preferably 20 minutes before a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Matiz Plus Tablet is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may cause confusion in them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Matiz Plus Tablet contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical
ChlordiazepoxideOxycodone
Severe

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical
How does the drug interact with Matiz Plus Tablet:
Taking Matiz Plus Tablet with Sodium oxybate increases the risk of breathing difficulty or low blood pressure.

How to manage the interaction:
Taking Matiz Plus Tablet with Sodium oxybate is generally avoided as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience dizziness, shortness of breath, excessive sweating, or blurred vision, contact your doctor. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideOxycodone
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of oxycodone with Matiz Plus Tablet can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking oxycodone and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as dizziness, shortness of breath, numbness in hands and feet, or palpitations, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideNalbuphine
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of nalbuphine with Matiz Plus Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking nalbuphine and Matiz Plus Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as dizziness, shortness of breath, numbness in hands and feet, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideFlumazenil
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of Flumazenil with Matiz Plus Tablet can increase the risk of developing fits.

How to manage the interaction:
Taking flumazenil and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, or blurred vision, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideDezocine
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of dezocine with Matiz Plus Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking dezocine and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as drowsiness, breathing difficulty, palpitations, or numbness in your hands and feet, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideHydrocodone
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of hydrocodone with Matiz Plus Tablet can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking hydrocodone and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as dizziness, breathing difficulty, palpitations, numbness in hands and feet, or headache, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideMethadone
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of methadone with Matiz Plus Tablet can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking methadone and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, breathing difficulty, difficulty concentrating, or numbness in hands and feet, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideCodeine
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of codeine with Matiz Plus Tablet can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking codeine and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. If you experience drowsiness, breathing difficulty, palpitations, numbness in hands and feet, or headache, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideTramadol
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of tramadol with Matiz Plus Tablet can increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking tramadol and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as dizziness, shortness of breath, numbness in hands and feet, or palpitations, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlordiazepoxideClozapine
Severe
How does the drug interact with Matiz Plus Tablet:
Co-administration of Matiz Plus Tablet with clozapine can increase the side effects.

How to manage the interaction:
Taking clozapine and Matiz Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as drowsiness, confusion, breathing difficulty, palpitations, and incoordination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight by exercising regularly.
  • Avoid carbonated and caffeinated beverages.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid deep-fried and spicy foods.
  • Foods containing probiotics may help in providing relief from gas and bloating.

Habit Forming

Yes

Therapeutic Class

ANTISPASMODICS

Matiz Plus Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Matiz Plus Tablet contains Mebeverine and Chlordiazepoxide. Mebeverine belongs to the class of antispasmodics that relaxes the muscles in the walls of the intestine and provides relief from painful muscle spasms. Thus, it reduces stomach pain caused by spasm, cramps, and gas formation, bloating, and discomfort. Chlordiazepoxide works by increasing GABA (nerve-calming agent) activity in the brain and decreasing the abnormal activity of nerve cells. Thereby, relaxes muscles, increases its calming action and reduces anxiety.

Matiz Plus Tablet may cause dependence in patients especially when taken at high doses, for longer durations, or in patients with a history of drug abuse or alcoholism. Therefore, take Matiz Plus Tablet only as prescribed.

Dizziness may be a side effect of Matiz Plus Tablet . However, you are recommended to avoid driving if you feel dizzy after taking Matiz Plus Tablet .

Yes, Matiz Plus Tablet reduces stomach pain which is a symptom of irritable bowel syndrome. Matiz Plus Tablet contains Mebeverine, an antispasmodic agent which reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Matiz Plus Tablet .

You are not recommended to take Matiz Plus Tablet with diazepam as co-administration of these two medicines may increase the risk of adverse effects such as drowsiness, dizziness, difficulty in concentrating, or confusion. However, please consult your doctor before taking Matiz Plus Tablet with other medicines.

Matiz Plus Tablet should be used with caution in elderly patients. Matiz Plus Tablet contains Chlordiazepoxide which may cause confusion in the elderly. However, please consult a doctor so that the dose may be adjusted appropriately.

Drug-Drug Interactions Checker List

  • CODEINE
  • MORPHINE
  • WARFARIN
  • DIAZEPAM
  • PHENOBARBITONE
  • PHENYTOIN
  • RIFAMPICIN
  • BACLOFEN
  • LEVODOPA
  • CIMETIDINE
  • OMEPRAZOLE
  • DIGOXIN
  • FUROSEMIDE
  • THEOPHYLLINE
  • CHLORPHENIRAMINE

Special Advise

Please consult a doctor if the symptoms persist or worsen after using Matiz Plus Tablet for more than 2 weeks.

Disease/Condition Glossary

Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods, and beverages, irregular hormone levels, certain food, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.

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