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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Maxiflo 250 Rotacaps

Maxiflo 250 Rotacaps is a combination medication primarily used to treat and prevent asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Maxiflo 250 Rotacaps is a combination of two medicines, namely: Formoterol fumarate (bronchodilator) and Fluticasone propionate (corticosteroids). Formoterol fumarate is a long-acting beta-agonist that relaxes the muscles in the airways and increases airflow to the lungs. Thereby making breathing easier by widening the airways. Fluticasone propionate acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Thereby, it provides relief from sneezing, runny or blocked nose and sinus discomfort. 

Use Maxiflo 250 Rotacaps as advised by the doctor. Your doctor will decide the dose and duration based on your medical condition. The common side effects of Maxiflo 250 Rotacaps include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, tiredness and noisy breathing. Most of these side effects of Maxiflo 250 Rotacaps do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not use Maxiflo 250 Rotacaps to treat sudden severe asthma symptoms or as a rescue inhaler. Please check with your doctor if you are pregnant, currently breastfeeding or taking any other prescribed or non-prescribed medicines. Maxiflo 250 Rotacaps is not recommended for children below five years of age. If you experience severe difficulty in breathing, please consult a doctor immediately so that alternative medicine may be prescribed. Regular monitoring of potassium levels is recommended while taking Maxiflo 250 Rotacaps as it may cause low potassium levels in the blood.

Uses of Maxiflo 250 Rotacaps

Asthma, Chronic Obstructive Pulmonary Disease (COPD)

Directions for Use

Inhaler: Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.Rotacap: Place the rotahaler between your teeth and seal it with your lips. Breathe with your mouth deeply while you press the rotahaler. Remove the device and breathe out normally.Autohaler: Autohaler is a breath-activated device that releases the medication when you inhale. Shake the autohaler well before using it. Hold it upright and push the lever up. Place the mouthpiece in your mouth and seal your lips around it. Breathe in slowly and deeply to release the medication from the device. Hold your breath for 10 seconds and breathe out normally. Push the lever down and replace the cap.Capsule: It is for inhalation use only; do not swallow. The capsule form contains powdered medication, which is to be inserted into the inhaling device/inhaler. It releases the medicine when you breathe deeply with your mouth through the inhaler.Rotadisk: Rotadisk is a silver-coloured aluminium foil disk that contains four blisters to place the medication. The medicine is to be inhaled through the mouth from the Rotadisk using a device called Diskhaler.

Medicinal Benefits

Maxiflo 250 Rotacaps is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Maxiflo 250 Rotacaps improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Maxiflo 250 Rotacaps is a combination of Formoterol fumarate and Fluticasone propionate. Formoterol fumarate is a long-acting β₂ agonist and bronchodilator. It relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone propionate belongs to the class of corticosteroids. It acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Together, Maxiflo 250 Rotacaps helps treat asthma and COPD.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Maxiflo 250 Rotacaps , let your doctor know if you have a history of heart, liver, kidney diseases, high blood pressure, hypokalaemia (low potassium levels in the blood), aneurysm (swelling of an artery), pheochromocytoma (adrenal gland tumour), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, chickenpox or measles, immune system problem, seizure (fits), osteoporosis (weak and brittle bones) and diabetes. Maxiflo 250 Rotacaps may cause hypokalemia (low potassium levels in the blood). Therefore they should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects. Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since nasal or inhaled corticosteroids like Fluticasone propionate can cause secondary infections. Maxiflo 250 Rotacaps can cause a rise in blood glucose levels. Hence monitor your blood glucose levels regularly and inform your doctor if you already have diabetes before using Maxiflo 250 Rotacaps . Please let your doctor know if you are pregnant or breastfeeding. Maxiflo 250 Rotacaps is not recommended for children below five years of age.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Maxiflo 250 Rotacaps with Mifepristone may make Maxiflo 250 Rotacaps less effective as a therapy.

How to manage the interaction:
Taking Maxiflo 250 Rotacaps with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Cladribine with Maxiflo 250 Rotacaps can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Maxiflo 250 Rotacaps and Cladribine together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
FluticasoneNelfinavir
Severe
How does the drug interact with Maxiflo 250 Rotacaps:
Taking Nelfinavir may increase the absorption of Maxiflo 250 Rotacaps into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Maxiflo 250 Rotacaps and Nelfinavir together, a doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Ketoconazole and Maxiflo 250 Rotacaps may significantly increase the absorption of Maxiflo 250 Rotacaps into the bloodstream.

How to manage the interaction:
If you are supposed to take Maxiflo 250 Rotacaps and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Maxiflo 250 Rotacaps:
Taking Ceritinib together with Maxiflo 250 Rotacaps may increase the blood levels of Maxiflo 250 Rotacaps.

How to manage the interaction:
If you are supposed to take Maxiflo 250 Rotacaps and Ceritinib together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Maxiflo 250 Rotacaps:
Indinavir may increase the absorption of Maxiflo 250 Rotacaps into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Maxiflo 250 Rotacaps and Indinavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor.
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Maxiflo 250 Rotacaps with Voriconazole may increase the absorption of Maxiflo 250 Rotacaps into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although Maxiflo 250 Rotacaps and Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneAmprenavir
Severe
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Amprenavir and Maxiflo 250 Rotacaps may significantly increase the absorption of Maxiflo 250 Rotacaps into the blood stream.

How to manage the interaction:
Co-administration of Amprenavir and Maxiflo 250 Rotacaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Atazanavir and Maxiflo 250 Rotacaps may significantly increase the absorption of Maxiflo 250 Rotacaps into the bloodstream.

How to manage the interaction:
Co-administration of Atazanavir and Maxiflo 250 Rotacaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Maxiflo 250 Rotacaps:
Co-administration of Maxiflo 250 Rotacaps with Clarithromycin may significantly increase the absorption of Maxiflo 250 Rotacaps into the blood stream.

How to manage the interaction:
Co-administration of Clarithromycin and Maxiflo 250 Rotacaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medicines, herbal or vitamin supplements without informing your pharmacist or doctor when you take Maxiflo 250 Rotacaps .
  • Know your triggers like allergens, such as pollen, dust and food items that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Maxiflo 250 Rotacaps consists of Formoterol fumarate (bronchodilator) and Fluticasone propionate (Fluticasone). Formoterol fumarate relaxes the muscles in the airways and increases airflow to the lungs. Fluticasone propionate acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Together, Maxiflo 250 Rotacaps helps treat asthma and COPD.

Maxiflo 250 Rotacaps may raise blood glucose levels. Therefore, please consult your doctor if you are diabetic. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.

Maxiflo 250 Rotacaps may decrease the potassium levels in your body. Please consult your doctor before taking Maxiflo 250 Rotacaps since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Maxiflo 250 Rotacaps may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Maxiflo 250 Rotacaps to experience this side effect. However, to avoid dry mouth, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. If the condition persists or worsens, please consult a doctor.

Maxiflo 250 Rotacaps is not recommended for use when taking Sotalol or vice versa. Sotalol and Maxiflo 250 Rotacaps have opposing effects on the body. Sotalol may also trigger asthma attacks or worsen breathing problems by narrowing the airways. Please consult your doctor before using other medicines with Maxiflo 250 Rotacaps .

No, Maxiflo 250 Rotacaps is not used for sudden breathing problems; your doctor may suggest a rescue inhaler for sudden breathing problems.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • BUDESONIDE
  • MOMETASONE
  • BECLOMETHASONE
  • VILANTEROL
  • SALMETEROL
  • ALBUTEROL
  • IPRATROPIUM
  • SOTALOL
  • METOPROLOL

Special Advise

  •  
  • It is advised to undergo a blood examination to check your potassium levels since Maxiflo 250 Rotacaps can cause low potassium levels in the blood (hypokalaemia).
  • Regularly monitor your blood sugar levels while using Maxiflo 250 Rotacaps since bronchodilators like Formoterol fumarate can cause low blood glucose levels.
  • Consult your diabetologist if you have diabetes before using Maxiflo 250 Rotacaps so that your insulin or other diabetic medication doses can be adjusted accordingly to maintain your blood sugar levels.
  •  

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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