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Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Maxigesic 500 mg/50 mg/500 mg Tablet MR

Maxigesic 500 mg/50 mg/500 mg Tablet MR belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). Maxigesic 500 mg/50 mg/500 mg Tablet MR is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long term(chronic) in nature. Musculoskeletal pain can be caused due to soft tissues (muscle, tendon, and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Maxigesic 500 mg/50 mg/500 mg Tablet MR is a fixed-dose combination composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Maxigesic 500 mg/50 mg/500 mg Tablet MR can be taken with or after the meal. To avoid stomach upset Maxigesic 500 mg/50 mg/500 mg Tablet MR can be taken with food or milk. It should be swallowed whole with a glass of water. Do not take Maxigesic 500 mg/50 mg/500 mg Tablet MR if your pain lasts for more than ten days or fever lasting for more than three days. Do not take a double dose if you missed one dose. Like all medicines, Maxigesic 500 mg/50 mg/500 mg Tablet MR may cause side effects, although not everybody gets them. Most of the side effects of Maxigesic 500 mg/50 mg/500 mg Tablet MR are drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. In case of any discomfort, speak with your doctor. 

Do not take Maxigesic 500 mg/50 mg/500 mg Tablet MR if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Maxigesic 500 mg/50 mg/500 mg Tablet MR may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Maxigesic 500 mg/50 mg/500 mg Tablet MR

Musculoskeletal pain.

Directions for Use

Take Maxigesic 500 mg/50 mg/500 mg Tablet MR as advised by your doctor. Preferably take it with a light meal. Swallow it as a whole, do not chew or crush it.

Medicinal Benefits

Maxigesic 500 mg/50 mg/500 mg Tablet MR is composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Maxigesic 500 mg/50 mg/500 mg Tablet MR

  • Drowsiness
  • Constipation
  • Diarrhoea
  • Stomach upset
  • Slight discolouration of urine
  • Ringing or buzzing sounds in the ears

Drug Warnings

Intake of Maxigesic 500 mg/50 mg/500 mg Tablet MR should be avoided in liver disease (like jaundice) and cardiovascular disease (like coronary heart disease). Contact your doctor if you have signs of liver disease like feeling exhausted, dark urine, not feeling hungry, stomach pain or upset, light coloured stools or yellow skin/eyes. After taking if you have possible allergic symptoms like difficulty in breathing, difficulty in swallowing, lips/face/throat swelling, chest tightness, or skin rash, contact the doctor immediately. Ensure your doctor is aware if you are pregnant or planning to get pregnant, breastfeeding, allergic to Maxigesic 500 mg/50 mg/500 mg Tablet MR or any other painkillers like aspirin, the problem of stomach ulcer or gastric bleeding, or taking any other OTC multivitamins, multi-minerals supplements.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ParacetamolLeflunomide
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Maxigesic 500 mg/50 mg/500 mg Tablet MR with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Maxigesic 500 mg/50 mg/500 mg Tablet MR is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ParacetamolLeflunomide
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Maxigesic 500 mg/50 mg/500 mg Tablet MR and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Teriflunomide with Maxigesic 500 mg/50 mg/500 mg Tablet MR may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Maxigesic 500 mg/50 mg/500 mg Tablet MR with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Maxigesic 500 mg/50 mg/500 mg Tablet MR and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of ketamine and Maxigesic 500 mg/50 mg/500 mg Tablet MR may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Maxigesic 500 mg/50 mg/500 mg Tablet MR together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Lomitapide and Maxigesic 500 mg/50 mg/500 mg Tablet MR may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Mipomersen with Maxigesic 500 mg/50 mg/500 mg Tablet MR may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Maxigesic 500 mg/50 mg/500 mg Tablet MR may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Maxigesic 500 mg/50 mg/500 mg Tablet MR, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Co-administration of Maxigesic 500 mg/50 mg/500 mg Tablet MR and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Maxigesic 500 mg/50 mg/500 mg Tablet MR:
Taking Dasatinib together with Maxigesic 500 mg/50 mg/500 mg Tablet MR may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Maxigesic 500 mg/50 mg/500 mg Tablet MR and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maxigesic 500 mg/50 mg/500 mg Tablet MR is commonly prescribed for relieving pain in both acute and chronic conditions and in cases of fever. Do not take the drug beyond its suggested dose and frequency.
  • Avoid driving while consuming Maxigesic 500 mg/50 mg/500 mg Tablet MR as it can cause dizziness in some individuals and hamper your focus and reflexes.
  • Avoid concomitant consumption of drugs containing the same chemicals as Maxigesic 500 mg/50 mg/500 mg Tablet MR as it can lead to overdosage and unwanted side effects.
  • Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Maxigesic 500 mg/50 mg/500 mg Tablet MR.
  • Avoid consuming alcohol while you are on Maxigesic 500 mg/50 mg/500 mg Tablet MR.

Habit Forming

No

Therapeutic Class

ANALGESICS

Maxigesic 500 mg/50 mg/500 mg Tablet MR Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, Maxigesic 500 mg/50 mg/500 mg Tablet MR should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Maxigesic 500 mg/50 mg/500 mg Tablet MR, take it in doses and duration mentioned by your doctor.

No, it is not advisable to take Maxigesic 500 mg/50 mg/500 mg Tablet MR with depression medication. Please inform your doctor if you are taking depression medicine before starting Maxigesic 500 mg/50 mg/500 mg Tablet MR.

Yes, Maxigesic 500 mg/50 mg/500 mg Tablet MR is a short term medication and if you feel better you can stop taking Maxigesic 500 mg/50 mg/500 mg Tablet MR, but only after consulting your doctor.

Maxigesic 500 mg/50 mg/500 mg Tablet MR is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

Yes, Maxigesic 500 mg/50 mg/500 mg Tablet MR is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Maxigesic 500 mg/50 mg/500 mg Tablet MR as it can be harmful.

No, Maxigesic 500 mg/50 mg/500 mg Tablet MR is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Maxigesic 500 mg/50 mg/500 mg Tablet MR in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contains diclofenac, paracetamol and Chlorzoxazone or not. If it contains these three medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

No, do not take Maxigesic 500 mg/50 mg/500 mg Tablet MR until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen or gallbladder problem. Your back pain may be due to kidney stone, pancreas swelling, or in women, pelvic disorders. Your arm pain (especially left arm) may be due to heart attack (myocardial infarction).

Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LISINOPRIL
  • HYDROCHLOROTHIAZIDE
  • RIVAROXABAN
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE
  • PREDNISONE

Special Advise

  • Maxigesic 500 mg/50 mg/500 mg Tablet MR is prescribed for relief from muscle pain and spasms.
  • It can cause drowsiness and hence activities involving focus and attention like driving must be avoided while on this medication.
  • Concomitant usage of alcohol with this medicine increase the risk of damage to liver and other side effects and hence alcohol consumption should be avoided while consuming this medication
  • Avoid simultaneous consumption of other painkillers or cough and cold medicines with this Maxigesic 500 mg/50 mg/500 mg Tablet MR as it may lead to overdose.

Disease/Condition Glossary

Musculoskeletal pain is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports related injury) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal

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