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About Mecosule Plus Capsule
Mecosule Plus Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.
Mecosule Plus Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).
You should take this medicine as prescribed by your doctor. The common side-effects of Mecosule Plus Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.
Do not take Mecosule Plus Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Mecosule Plus Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse. It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Mecosule Plus Capsule may cause dizziness or drowsiness. Mecosule Plus Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor.
Uses of Mecosule Plus Capsule

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Key Benefits
Mecosule Plus Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Mecosule Plus Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.
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Drug Warnings
Mecosule Plus Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Mecosule Plus Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Mecosule Plus Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Mecosule Plus Capsule , inform your doctor as Mecosule Plus Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Mecosule Plus Capsule . In such cases, inform your doctor immediately.
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Special Advise
Mecosule Plus Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Mecosule Plus Capsule block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.
Mecosule Plus Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.
Mecosule Plus Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Mecosule Plus Capsule should be stopped gradually over a minimum of 1 week.
Mecosule Plus Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Mecosule Plus Capsule . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.
Mecosule Plus Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Mecosule Plus Capsule .
You may notice pain improvement within 2-3 days after taking Mecosule Plus Capsule . However, it may take 2-3 months for your symptoms to improve depending on your health condition.
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