Mediace Gel 30 gm belongs to the class of medications called 'Non-steroidal anti-inflammatory drugs (NSAID)' used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. 

Mediace Gel 30 gm is a combination of six drugs: Diclofenac diethylamine, Capsaicin, Methyl salicylate, Linseed oil, Benzyl alcohol, and Menthol. Diclofenac diethylamine and Methyl salicylate are painkillers, which work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Capsaicin is a natural extract of chilli pepper that works by blocking the pain messengers to the nerves. Linseed oil possesses an anti-inflammatory agent that inhibits inflammatory mediators like leukotrienes (LK), reducing inflammation. On the other hand, Menthol and Benzyl alcohol are soothing and cooling agents which provide a cooling sensation by dilating the blood vessels, followed by an analgesic effect. It also enhances the penetration of drugs. Together, Mediace Gel 30 gm helps provide relief from mild to moderate pain in various musculoskeletal and joint conditions. 

Mediace Gel 30 gm is for external use only. In some cases, you may experience certain common side-effects such as application site reactions like itching, irritation, redness, and burning sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Mediace Gel 30 gm can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Mediace Gel 30 gm. Mediace Gel 30 gm increases the chances of stomach ulcers and bleeding. Do not use Mediace Gel 30 gm if you are pregnant or breastfeeding unless prescribed. Mediace Gel 30 gm is not recommended for children below 14years as safety and efficacy have not been established. Avoid or limit exposure to natural or artificial sunlight as Mediace Gel 30 gm may cause sensitivity. Do not use any other NSAIDs for pain relief along with Mediace Gel 30 gm unless prescribed.

Mediace Gel 30 gm is a combination of Diclofenac diethylamine, Capsaicin, Methyl salicylate, Linseed oil, Benzyl alcohol, and Menthol. Mediace Gel 30 gm is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Diclofenac diethylamine and Methyl salicylate work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Capsaicin exerts an analgesic effect by blocking the pain messengers to the nerves. Linseed oil helps in reducing inflammation. Menthol and Benzyl alcohol provide a cooling sensation by dilating the blood vessels, followed by an analgesic effect. It also enhances the penetration of drugs. Together, Mediace Gel 30 gm helps in providing relief from pain and inflammation. 

• Itching
• Irritation
• Redness
• Burning sensation

Do not use Mediace Gel 30 gm if you are allergic to any of its contents. Inform your doctor in advance if you have/had severe heart problems, stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems or inflammation of intestines. Do not use Mediace Gel 30 gm if you experience asthma, urticaria, or allergy after taking a pain killer. Inform your doctor before using Mediace Gel 30 gm if you are taking any painkillers orally. Do not use Mediace Gel 30 gm if you are pregnant or breastfeeding unless prescribed. Mediace Gel 30 gm is not recommended for children below 14years as the safety and effectiveness have not been established.

Drug-Drug Interaction: Mediace Gel 30 gm may have interaction with pain killer medicines (aspirin), anticoagulant medicines (warfarin), anti-rheumatoid (methotrexate), and immunosuppressants (cyclosporine).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have heart problems, stomach ulcer or perforation and bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems or inflammation of intestines before using Mediace Gel 30 gm.

• ASPIRIN
• WARFARIN
• METHOTREXATE
• CYCLOSPORINE

• Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Massages can also be helpful.
• Avoid freezing and hot temperatures.
• Avoid wearing tight-fitting clothes, instead, wear loose garments.
• Rest well, get plenty of sleep.
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
• Stay hydrated, drink plenty of water.

• Do not apply on open wounds, cuts, abrasions or infected wounds.
• Do not apply any bandages after application of Mediace Gel 30 gm unless suggested by your doctor.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic, can be localized or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Musculoskeletal pain symptoms include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, cracking, or popping sound at the joints.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.