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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Megatas Plus 25mg Combikit Tablet

Megatas Plus 25mg Combikit Tablet is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control.
 
Megatas Plus 25mg Combikit Tablet contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Megatas Plus 25mg Combikit Tablet helps in treating overactive bladder.
 
You are advised to take Megatas Plus 25mg Combikit Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Megatas Plus 25mg Combikit Tablet is not recommended for children as safety and efficacy have not been established. Megatas Plus 25mg Combikit Tablet may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption along with Megatas Plus 25mg Combikit Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Megatas Plus 25mg Combikit Tablet to rule out any side effects/interactions.

Uses of Megatas Plus 25mg Combikit Tablet

Overactive bladder syndrome

Directions for Use

Swallow Megatas Plus 25mg Combikit Tablet as a whole with water; do not chew or break it.

Medicinal Benefits

Megatas Plus 25mg Combikit Tablet is a combination of two drugs, namely: Solifenacin and Mirabegron. Megatas Plus 25mg Combikit Tablet is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, dysuria (painful or difficult urination). Solifenacin is an anti-cholinergic that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron is a beta-3 adrenergic agonist which relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Megatas Plus 25mg Combikit Tablet helps in treating an overactive bladder.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Megatas Plus 25mg Combikit Tablet if you are allergic to any of its contents. Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Megatas Plus 25mg Combikit Tablet is not recommended for children. Megatas Plus 25mg Combikit Tablet may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption with Megatas Plus 25mg Combikit Tablet as it could lead to increased dizziness. 

Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Quit smoking.
  • Take 6-8glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Megatas Plus 25mg Combikit Tablet Substitute

Substitutes safety advice
  • Megatas Plus 50mg Combikit Tablet 1's

    by AYUR

    316.80per tablet

Author Details

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FAQs

Megatas Plus 25mg Combikit Tablet contains Solifenacin and Mirabegron. Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Megatas Plus 25mg Combikit Tablet helps in treating an overactive bladder.

There is some overlap between the symptoms of both OAB and BPH. OAB occurs due to uncontrolled urinary bladder muscle contractions. The main symptom of OAB is a sudden urge to urinate that's hard to control, which is stressful. On the other hand, BPH occurs due to an enlarged prostate gland, which puts pressure on the urinary bladder, thereby causing pain during urination.

Dry mouth could be a side effect of Megatas Plus 25mg Combikit Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Megatas Plus 25mg Combikit Tablet might cause hypertension. Therefore, consult your doctor before taking Megatas Plus 25mg Combikit Tablet if you have high blood pressure.

Constipation could be a side-effect of Megatas Plus 25mg Combikit Tablet. Eat fibre-rich food and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ACETAMINOPHEN
  • ALBUTEROL

Disease/Condition Glossary

Overactive bladder (OAB): Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control. The contraction or tightening of bladder muscles causes bladder spasms. Continuous contractions may cause an urge to urinate. Overactive bladder is characterised by involuntary leakage of urine, excessive urination, and urgent need to urinate. The common causes of bladder spasms are urinary tract infections, drinking too much caffeine or alcohol, diabetes, constipation, impaired kidney function, bladder stones, enlarged prostate, or neurological disorders. Symptoms of overactive bladder include urinating more than 8 times a day and more than 2 times at night, strong and sudden need to urinate, leakage of urine, and loss of bladder control.

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