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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer :

Silicon Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

About Meglisil 2mg/500mg Tablet SR

Meglisil 2mg/500mg Tablet SR belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Meglisil 2mg/500mg Tablet SR is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

Take Meglisil 2mg/500mg Tablet SR as prescribed by your doctor. You are advised to take Meglisil 2mg/500mg Tablet SR for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Meglisil 2mg/500mg Tablet SR do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Meglisil 2mg/500mg Tablet SR or any other medicines, please tell your doctor. Meglisil 2mg/500mg Tablet SR is not recommended for children. Avoid breastfeeding while taking Meglisil 2mg/500mg Tablet SR as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Meglisil 2mg/500mg Tablet SR as it may harm the unborn baby. Avoid alcohol consumption with Meglisil 2mg/500mg Tablet SR as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Meglisil 2mg/500mg Tablet SR. Take short, frequent meals and avoid prolonged fasting while taking Meglisil 2mg/500mg Tablet SR.

Uses of Meglisil 2mg/500mg Tablet SR

Type 2 diabetes mellitus

Directions for Use

Take Meglisil 2mg/500mg Tablet SR as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

Meglisil 2mg/500mg Tablet SR contains Glimepiride and Metformin used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Meglisil 2mg/500mg Tablet SR

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste

Drug Warnings

If you are allergic to Meglisil 2mg/500mg Tablet SR or any other medicines, please tell your doctor. Meglisil 2mg/500mg Tablet SR is not recommended for children. Avoid breastfeeding while taking Meglisil 2mg/500mg Tablet SR as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Meglisil 2mg/500mg Tablet SR as it may harm the unborn baby. Avoid alcohol consumption with Meglisil 2mg/500mg Tablet SR as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Meglisil 2mg/500mg Tablet SR. Take short, frequent meals and avoid prolonged fasting while taking Meglisil 2mg/500mg Tablet SR. Beware of symptoms of hypoglycemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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MetforminIoglicic acid
Critical
MetforminIohexol
Critical

Drug-Drug Interactions

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MetforminIoglicic acid
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Ioglicic acid with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iohexol with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Ioglycamic acid with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iopromide with Meglisil 2mg/500mg Tablet SR can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Meglisil 2mg/500mg Tablet SR is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Meglisil 2mg/500mg Tablet SR and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Ioversol with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iotroxic acid with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iopentol with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iopanoic acid with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Meglisil 2mg/500mg Tablet SR:
Co-administration of Iodixanol with Meglisil 2mg/500mg Tablet SR can increase the risk of side effects.

How to manage the interaction:
Taking Meglisil 2mg/500mg Tablet SR with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain healthy body weight as obesity is also related to the onset of diabetes.
  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Meglisil 2mg/500mg Tablet SR Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Meglisil 2mg/500mg Tablet SR contains two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

You are not recommended to take Meglisil 2mg/500mg Tablet SR with phenytoin as it may reduce the effect of Meglisil 2mg/500mg Tablet SR and increase blood sugar levels. However, please consult a doctor before using Meglisil 2mg/500mg Tablet SR with other medicines.

Meglisil 2mg/500mg Tablet SR may increase the risk of low blood sugar levels especially with alcohol intake, exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.

You are not recommended to stop taking Meglisil 2mg/500mg Tablet SR on your own as discontinuing Meglisil 2mg/500mg Tablet SR suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Meglisil 2mg/500mg Tablet SR, please consult your doctor so that alternative medicine may be prescribed.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • TRIMETHOPRIM
  • VERAPAMIL
  • CIMETIDINE
  • DOLUTEGRAVIR
  • RANOLAZINE
  • VANDETANIB
  • CRIZOTINIB
  • OLAPARIB
  • FLUCONAZOLE
  • MICONAZOLE
  • ACETAZOLAMIDE
  • INSULIN
  • PHENYTOIN

Special Advise

Regular blood tests are recommended while taking Meglisil 2mg/500mg Tablet SR to monitor blood sugar levels.

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increase chance of heart attack or stroke.

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