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About Megoal Trio 20mg/10mg/12.5mg Tablet
Megoal Trio 20mg/10mg/12.5mg Tablet belongs to the class of medicines called hypertensives primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.
Megoal Trio 20mg/10mg/12.5mg Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone together help in lowering raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone (diuretic) removes extra water, certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.
Take Megoal Trio 20mg/10mg/12.5mg Tablet with food or as advised by the doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on the dose and duration based on your medical condition. You may experience headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Megoal Trio 20mg/10mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase the risk of getting stroke and heart diseases. Megoal Trio 20mg/10mg/12.5mg Tablet should be taken with caution in patients with chest pain (angina), kidney disease, heart failure, low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Megoal Trio 20mg/10mg/12.5mg Tablet can be prescribed accordingly. Do not use Megoal Trio 20mg/10mg/12.5mg Tablet if you cannot urinate, are dehydrated, and increase fluid intake. Please inform your doctor if you are taking any other medicines or are allergic to this medicine. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.
Uses of Megoal Trio 20mg/10mg/12.5mg Tablet
Directions for Use
Medicinal Benefits
Megoal Trio 20mg/10mg/12.5mg Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Clindipine, and Chlorthalidone, which together help in lowering raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Chlorthalidone is a diuretic that removes extra water, certain electrolytes from the body and efficiently reduces blood pressure.
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Side Effects of Megoal Trio 20mg/10mg/12.5mg Tablet
Drug Warnings
Megoal Trio 20mg/10mg/12.5mg Tablet should not be given to the people allergic to Megoal Trio 20mg/10mg/12.5mg Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Megoal Trio 20mg/10mg/12.5mg Tablet can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Megoal Trio 20mg/10mg/12.5mg Tablet and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Megoal Trio 20mg/10mg/12.5mg Tablet as it is contraindicated. Megoal Trio 20mg/10mg/12.5mg Tablet contain hydrochlorothiazide which can cause hypokalaemia (low potassium), hyponatremia (low sodium) and hypomagnesemia (low magnesium). So regular monitoring of electrolytes is required while taking treatment with Megoal Trio 20mg/10mg/12.5mg Tablet. Do not take Megoal Trio 20mg/10mg/12.5mg Tablet if you have low or no urine output, allergic to other sulfonamide antibiotics, or taking aliskiren and have diabetes. Drinking alcohol while using Megoal Trio 20mg/10mg/12.5mg Tablet can cause you to have low blood pressure, so avoid intake of alcoholic beverages.
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It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.
In case you have missed a dose of Megoal Trio 20mg/10mg/12.5mg Tablet, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Megoal Trio 20mg/10mg/12.5mg Tablet will lead to low blood pressure.
Yes, Megoal Trio 20mg/10mg/12.5mg Tablet is contraindicated in people with known allergy to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided in women who are in the second and third trimesters of their pregnancy.
Yes, Megoal Trio 20mg/10mg/12.5mg Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Megoal Trio 20mg/10mg/12.5mg Tablet. If you still feel excessively thirsty, please consult your doctor and advise for the best results of Megoal Trio 20mg/10mg/12.5mg Tablet.
It's unlikely that Megoal Trio 20mg/10mg/12.5mg Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For the best advice, consult your doctor.
Yes, Megoal Trio 20mg/10mg/12.5mg Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Yes, Megoal Trio 20mg/10mg/12.5mg Tablet can cause an upset stomach. So, it is preferred to take Megoal Trio 20mg/10mg/12.5mg Tablet with food to avoid it.
High blood pressure in the pregnancy stage may cause eclampsia that can be harmful to both baby and mother. So, during the pregnancy, you should have regular blood pressure monitoring.
Megoal Trio 20mg/10mg/12.5mg Tablet if stopped abruptly can lead to withdrawal symptoms. So, before stopping Megoal Trio 20mg/10mg/12.5mg Tablet, consult your doctor; your dose will be lowered gradually to avoid unpleasant side effects of Megoal Trio 20mg/10mg/12.5mg Tablet.
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Special Advise
Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
Disease/Condition Glossary
Blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.