Mekgud D 1500/50 Tablet 10's belongs to a class of medications called 'non-steroidal anti-inflammatory (NSAID)/ anti-inflammatory and antirheumatic agents, non-steroids', primarily taken for reducing the pain of osteoarthritis (OA) in specific large and small joints. Osteoarthritis is a chronic (lifelong) joint condition in which Glucosamine sulfate (a chemical found in the human body, especially in joints) gets reduced. The body uses this fluid to produce other chemicals required to make ligaments, cartilage, tendons, and the thick fluid surrounding joints. When this chemical gets reduced, then the cartilage breaks down and becomes thin, which causes friction between the bones leading to wear and tear (damage) of the joint tissues leading to pain, stiffness, inflammation, and reduced locomotion. 

The Mekgud D 1500/50 Tablet 10's compromises two medicines, namely Diacerein and Glucosamine. Diacerein restricts the action of a protein responsible for causing inflammation and destruction of cartilage or osteoarthritis. At the same time, Glucosamine sulfate is a natural protein found in the body used by the body to produce various chemicals responsible for building ligaments, cartilage, tendons, and the thick fluid surrounding joints. Taking Mekgud D 1500/50 Tablet 10's may either enhance the cartilage and fluid surrounding joints or prevent both components' breakdown. In combination, both help form cartilage (the soft tissue that cushions the joints) and make the joints lubricated for better movement and flexibility. Mekgud D 1500/50 Tablet 10's relieves pain, thereby improving joint function and helping individuals restore their quality of life. It also increases the cushioning and lubrication of joints that, provide relief in pain and easily do physical activity. 

Take Mekgud D 1500/50 Tablet 10's as prescribed by your doctor. You are suggested to take Mekgud D 1500/50 Tablet 10's as long as your doctor has prescribed it after checking your medical condition. Sometimes, you may experience certain common side effects, such as headache, tiredness, nausea, abdominal pain, indigestion, diarrhoea, constipation, and wind. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these undesirable effects persistently.

Mekgud D 1500/50 Tablet 10's is not allowed to be used in children younger than 18. Consult your doctor if you have ever had blood clots or circulation problems in your legs or if you are pregnant or planning to be pregnant, as this may harm an unborn baby. Tell your doctor if you are breastfeeding as It may not be safe to breastfeed a baby while taking Mekgud D 1500/50 Tablet 10's. People with joint infection or skin disease in the affected area should consult a doctor before taking Mekgud D 1500/50 Tablet 10's. People dealing with impaired glucose tolerance, kidney or liver dysfunction risk factors for heart (cardiovascular) disease, and who have asthma should take Mekgud D 1500/50 Tablet 10's with caution.

The Mekgud D 1500/50 Tablet 10's compromises two medicines, namely Diacerein and Glucosamine. Diacerein restricts the action of a protein responsible for causing inflammation and destruction of cartilage or osteoarthritis. At the same time, Glucosamine sulfate is a natural protein found in the body used by the body to produce a variety of chemicals responsible for building ligaments, cartilage, tendons, and the thick fluid surrounding joints. Taking Mekgud D 1500/50 Tablet 10's may either enhance the cartilage and fluid surrounding joints or prevent both components' breakdown. In combination, both help form cartilage (the soft tissue that cushions the joints) and make the joints lubricated for better movement and flexibility. Mekgud D 1500/50 Tablet 10's relieves pain, thereby improving joint function and helping individuals restore their quality of life. It also increases the cushioning and lubrication of joints, provides relief from pain and easily do physical activity.

• Nausea
• Diarrhoea
• Headache
• Tiredness
• Indigestion
• Constipation
• Abdominal pain
• Wind (flatulence)
   

Consumption of alcohol should be avoided during the treatment with Mekgud D 1500/50 Tablet 10's as it may lead to an increased risk of liver damage. Patients with blood clots or leg circulation problems should not take Mekgud D 1500/50 Tablet 10's. Although it is generally a safe medicine to use, it should be avoided in patients with liver and kidney disease as the Mekgud D 1500/50 Tablet 10's may harm the liver and renal functions. Use with caution in pregnancy and breastfeeding. Do not self-administer Mekgud D 1500/50 Tablet 10's if you are pregnant or are nursing. Although Mekgud D 1500/50 Tablet 10's provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, it is strongly recommended to remain physically active as much as your condition allows to achieve the best results. Adopting a healthy lifestyle and a diet containing high proteins is the mainstay for managing arthritic conditions.

Drug-Drug Interactions: Mekgud D 1500/50 Tablet 10's can interact with medicines used for blood thinning (Warfarin), Medications for cancer (Paclitaxel), painkillers (Acetaminophen), Antidiabetes drugs (glimepiride, pioglitazone). Inform your doctor if you are using any of these.

Drug-Food Interactions: Avoid intake of Vitamin E, St. John’s wort (antidepressant), and Ginkgo Biloba with Mekgud D 1500/50 Tablet 10's. 

Drug-Disease Interactions: People dealing with impaired glucose tolerance, kidney or liver dysfunction risk factor for heart (cardiovascular) disease, and suffering from asthma should take Mekgud D 1500/50 Tablet 10's with caution.

• WARFARIN
• PACLITAXEL
• ACETAMINOPHEN
• GLIMEPIRIDE
• PIOGLITAZONE

• Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
• Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
• Including fish like salmon, trout, tuna, and sardines in your daily diet. These fishes are enriched with omega-3 fatty acids with a minimum level of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation condition. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• X- rays of affected joints is done to identify osteoarthritis 

Pain: Pain is an unpleasant and emotional experience associated with tissue damage. It allows the body to react and prevent further tissue damage. Pain can be short-term (acute) or long-term (chronic). Pain perception can differ from person to person, from tolerable to non-tolerable.

Osteoarthritis: Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, and dislocated joints and ligaments.