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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

RABEPRAZOLE-20MG

Manufacturer/Marketer :

Globus Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mepraz Tablet

Mepraz Tablet belongs to a group of antiulcer medicines called proton pump inhibitors used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Mepraz Tablet contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

You are advised to take Mepraz Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, and runny nose. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor if you have a stomach tumour or liver disease. On long-term treatment, Mepraz Tablet may cause low magnesium levels, vitamin B12 levels and increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Mepraz Tablet may cause dizziness and sleepiness, so drive only if you are alert. Mepraz Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol along with Mepraz Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Mepraz Tablet

Gastro-oesophageal reflux disease (GERD), duodenal ulcers, Zollinger-Ellison syndrome.

Directions for Use

Take Mepraz Tablet 30 minutes prior to food. Mepraz Tablet should be swallowed as a whole with a glass of water; do not chew, or crush the tablet/capsule.

Medicinal Benefits

Mepraz Tablet belongs to a group of antiulcer medicines called proton pump inhibitors. Mepraz Tablet is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome. Mepraz Tablet works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mepraz Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not take Mepraz Tablet if you are allergic to any of its contents. Inform your doctor if you have a stomach tumour, liver disease, or if you are due to have Chromogranin A blood test. On long-term treatment, Mepraz Tablet may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor before starting Mepraz Tablet if you are pregnant or breastfeeding. Mepraz Tablet may cause dizziness and sleepiness, so drive only if you are alert. Mepraz Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol along with Mepraz Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid. Prolonged intake of Mepraz Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical
How does the drug interact with Mepraz Tablet:
Using rilpivirine together with Mepraz Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Mepraz Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
Mepraz Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Mepraz Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
When taken together, Mepraz Tablet, through decreasing stomach acid, can reduce atazanavir absorption and blood levels, making the medication less effective.

How to manage the interaction:
Although taking Mepraz Tablet with atazanavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
Taking Mepraz Tablet and carbamazepine may possibly reduce the effects of Mepraz Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking Mepraz Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mepraz Tablet:
When taken together Mepraz Tablet may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness.

How to manage the interaction:
Although taking Mepraz Tablet with gefitinib can lead to interaction, they can be taken if recommended by a doctor. However, if you have no other treatment options, it is suggested that you take gefitinib 12 hours before or after Mepraz Tablet to reduce the impact of the interaction. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
Mepraz Tablet may interfere with pazopanib absorption and reduces its effectiveness.

How to manage the interaction:
Although taking Mepraz Tablet with pazopanib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
Coadministration of Mepraz Tablet with methotrexate may increase the levels and side effects of Mepraz Tablet.

How to manage the interaction:
Although there is a possible interaction between Mepraz Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
How does the drug interact with Mepraz Tablet:
When Mepraz Tablet is used with citalopram the blood levels of citalopram may increase, increasing the risk of certain adverse effects, such as an abnormal heart rhythm, which can be serious.

How to manage the interaction:
Although taking Mepraz Tablet and citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid/pounding heartbeats while taking these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
When taken together Mepraz Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking Mepraz Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mepraz Tablet:
Taking Mepraz Tablet and Dasatinib together may decrease the blood levels of Dasatinib.

How to manage the interaction:
Although taking Mepraz Tablet with Dasatinib can lead to interaction, they can be taken if recommended by a doctor. If you experience any unusual symptoms, visit a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTIULCERS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mepraz Tablet works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Talk to your doctor if you do not feel better even after taking Mepraz Tablet for 14 days. Do not take Mepraz Tablet for longer durations unless prescribed by the doctor. If Mepraz Tablet is prescribed for longer durations, a regular check-up is advised.

Do not discontinue Mepraz Tablet without consulting your doctor. To treat your condition effectually, continue taking Mepraz Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Mepraz Tablet .

Diarrhoea might be a side-effect of Mepraz Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Mepraz Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

Dry mouth could be a side-effect of Mepraz Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

On long term treatment, Mepraz Tablet might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • CLOPIDOGREL
  • LEVOTHYROXINE SODIUM
  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE
  • CYANOCOBALAMIN
  • AMITRIPTYLINE
  • DIAZEPAM
  • ZOLPIDEM

Special Advise

  • Inform your doctor before taking Mepraz Tablet if you are due to have Chromogranin A blood test.
  • Mepraz Tablet may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Mepraz Tablet .

Disease/Condition Glossary

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Duodenal ulcer: It is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining (first part of the small intestine, i.e., the duodenum).

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

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