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  1. Home
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  3. MERITAL 5MG TABLET

MERITAL 5MG TABLET, Pack of 10 TabletS
Not for online sale
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

AMITRIPTYLINE-25MG + CHLORDIAZEPOXIDE-5MG

Manufacturer/Marketer :

An Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About MERITAL 5MG TABLET

MERITAL 5MG TABLET is a combination medicine used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

MERITAL 5MG TABLET is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take MERITAL 5MG TABLET only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take MERITAL 5MG TABLET if you are pregnant as it may cause birth defects. Consult your doctor before taking MERITAL 5MG TABLET if you are breastfeeding. Avoid driving or operating machinery as MERITAL 5MG TABLET causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with MERITAL 5MG TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of MERITAL 5MG TABLET

Depression associated with anxiety

Directions for Use

Take MERITAL 5MG TABLET with or without food. Swallow MERITAL 5MG TABLET as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

MERITAL 5MG TABLET is a combination of two drugs: Amitriptyline and Chlordiazepoxide. MERITAL 5MG TABLET is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood treats depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. MERITAL 5MG TABLET has a calming effect on various functions of the brain. Thereby, MERITAL 5MG TABLET helps in treating anxiety and depression. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take MERITAL 5MG TABLET if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with MERITAL 5MG TABLET as it may result in increased sedation, depression, coma and death. MERITAL 5MG TABLET should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking MERITAL 5MG TABLET if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking MERITAL 5MG TABLET if you have a history of drug abuse, addiction or alcohol abuse as MERITAL 5MG TABLET may cause dependence. Do not take MERITAL 5MG TABLET if you are pregnant, as it may cause birth defects. Consult your doctor before taking MERITAL 5MG TABLET if you are breastfeeding. Avoid driving or operating machinery as MERITAL 5MG TABLET causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with MERITAL 5MG TABLET as it could lead to increased drowsiness and dizziness. MERITAL 5MG TABLET should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interactions

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AmitriptylinePotassium chloride
Critical
AmitriptylineThioridazine
Critical

Drug-Drug Interactions

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AmitriptylinePotassium chloride
Critical
How does the drug interact with Merital 5mg Tablet:
The combination of Merital 5mg Tablet and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Merital 5mg Tablet and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Merital 5mg Tablet:
Merital 5mg Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Merital 5mg Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineTranylcypromine
Critical
How does the drug interact with Merital 5mg Tablet:
Taking Tranylcypromine with Merital 5mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Merital 5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
AmitriptylineFurazolidone
Critical
How does the drug interact with Merital 5mg Tablet:
Combining Furazolidone with Merital 5mg Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Merital 5mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Merital 5mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylinePimozide
Critical
How does the drug interact with Merital 5mg Tablet:
Combining Merital 5mg Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Merital 5mg Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineBepridil
Critical
How does the drug interact with Merital 5mg Tablet:
Combining Merital 5mg Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Merital 5mg Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSelegiline
Critical
How does the drug interact with Merital 5mg Tablet:
Co-administration of Merital 5mg Tablet together with Selegiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selegiline and Merital 5mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Merital 5mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineIsocarboxazid
Critical
How does the drug interact with Merital 5mg Tablet:
Combining Isocarboxazid with Merital 5mg Tablet can increase the risk of serotonin syndrome (increase serotonin hormone).

How to manage the interaction:
Although using Isocarboxazid and Merital 5mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Merital 5mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineDronedarone
Critical
How does the drug interact with Merital 5mg Tablet:
Combining Merital 5mg Tablet and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Merital 5mg Tablet with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineCisapride
Critical
How does the drug interact with Merital 5mg Tablet:
Coadministration of Merital 5mg Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Merital 5mg Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

Yes

Therapeutic Class

PSYCHOTHERAPEUTICS

MERITAL 5MG TABLET Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

MERITAL 5MG TABLET contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.

MERITAL 5MG TABLET may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Do not discontinue MERITAL 5MG TABLET without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking MERITAL 5MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking MERITAL 5MG TABLET.

Dry mouth could be a side-effect of MERITAL 5MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Constipation might occur as a side-effect of MERITAL 5MG TABLET. Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • VENLAFAXINE
  • GABAPENTIN
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE SODIUM
  • ALPRAZOLAM
  • LORAZEPAM
  • FLUTICASONE+SALMETEROL
  • FUROSEMIDE
  • MORPHINE

Special Advise

  • Do not stop taking MERITAL 5MG TABLET on your own; sudden stopping of MERITAL 5MG TABLET may cause withdrawal symptoms. Consult your doctor if you have any concerns, the doctor may reduce the dose gradually.
  • Consult your doctor immediately if you develop any suicidal thoughts.
  • Women of childbearing age should use effective contraception while taking MERITAL 5MG TABLET.

Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use and medical conditions. Symptoms of depression include loss of interest, hopelessness, difficulty concentrating, appetite changes, irritability, feeling of emptiness, sadness and restlessness.

Anxiety: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress, in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone, at any age. Anxiety may cause a panic attacks, obsessive-compulsive disorder and post-traumatic stress disorder. The exact cause of anxiety is unknown, but it might be due to genetic or environmental factors. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating and difficulty falling asleep.

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