Mertabto 10 Tablet 10's

Written By Veda Maddala , M Pharmacy

Reviewed By Sunny S , MBBS

MRP ₹48

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₹4.8 Cashback (10%)

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Whats That

About Mertabto 10 Tablet

Mertabto 10 Tablet belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

Mertabto 10 Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Mertabto 10 Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take Mertabto 10 Tablet as prescribed by your doctor. You are advised to take Mertabto 10 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of Mertabto 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Mertabto 10 Tablet or any other medicines, please tell your doctor. Avoid taking Mertabto 10 Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Mertabto 10 Tablet and for 3 months after completing the course of Mertabto 10 Tablet to prevent pregnancy. Mertabto 10 Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as Mertabto 10 Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Mertabto 10 Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

Uses of Mertabto 10 Tablet

Blood cancer (Acute lymphoblastic leukaemia)

Directions for Use

Take Mertabto 10 Tablet with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Mertabto 10 Tablet contains Mercaptopurine, an anticancer drug used to treat blood cancer. Mertabto 10 Tablet interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, Mertabto 10 Tablet stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells.

Storage

Keep Mertabto 10 Tablet out of reach and sight of children.

Side effects of Mertabto 10 Tablet

Less Hunger

Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
Prefer foods high in fiber to help feel full for a long time.
If you have decreased appetite, eat only when you are hungry.
Eat several small meals or snacks all day.
Try to take only small sips of fluids while eating.

Pale Skin

Unusual Bleeding

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

If you are allergic to Mertabto 10 Tablet or any other medicines, please tell your doctor. Avoid taking Mertabto 10 Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Mertabto 10 Tablet and 3 months after completing the course of Mertabto 10 Tablet to prevent pregnancy. Mertabto 10 Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Mertabto 10 Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as Mertabto 10 Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Mertabto 10 Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking Mertabto 10 Tablet to cause infections.

Drug-Drug Interactions

MercaptopurineRotavirus vaccine

Critical

MercaptopurineYellow fever vaccine

Critical

Drug-Drug Interactions

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MercaptopurineRotavirus vaccine

Critical

How does the drug interact with Mertabto 10 Tablet:
When Rotavirus vaccine is used together with Mertabto 10 Tablet, its effectiveness may be reduced.

How to manage the interaction:
Taking Mertabto 10 Tablet with the Rotavirus vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.

MercaptopurineYellow fever vaccine

Critical

How does the drug interact with Mertabto 10 Tablet:
Co-administration of the Yellow fever vaccine with Mertabto 10 Tablet can increase the risk of infection.

How to manage the interaction:
Taking Mertabto 10 Tablet with the Yellow fever vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.

MercaptopurineBCG vaccine

Critical

How does the drug interact with Mertabto 10 Tablet:
Co-administration of the BCG vaccine with Mertabto 10 Tablet together can increase the risk of infection.

How to manage the interaction:
Taking Mertabto 10 Tablet with BCG vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.

MercaptopurineFebuxostat

Critical

How does the drug interact with Mertabto 10 Tablet:
Coadministration of Mertabto 10 Tablet with Febuxostat can increase the blood levels of Mertabto 10 Tablet.

How to manage the interaction:
Taking Mertabto 10 Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

MercaptopurineTalimogene laherparepvec

Critical

How does the drug interact with Mertabto 10 Tablet:
Co-administration of Talimogene laherparepvec with Mertabto 10 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mertabto 10 Tablet with Talimogene laherparepvec is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.

MercaptopurineVoclosporin

Severe

How does the drug interact with Mertabto 10 Tablet:
Co-administration of Mertabto 10 Tablet with Voclosporin can increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Mertabto 10 Tablet and Voclosporin, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - like feeling unwell, having a high temperature, stomach problems, a sore throat, body aches, difficulty breathing, losing weight, or experiencing pain while urinating - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

MercaptopurineMipomersen

Severe

How does the drug interact with Mertabto 10 Tablet:
Co-administration of Mipomersen and Mertabto 10 Tablet together can increase the risk of side effects.

How to manage the interaction:
Taking Mertabto 10 Tablet with Mipomersen together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, stomach ache, bleeding, or liver damage, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

MercaptopurineClozapine

Severe

How does the drug interact with Mertabto 10 Tablet:
Co-administration of Mertabto 10 Tablet with Clozapine can increase the risk of neutropenia (lower white blood cell count), which may increase the risk of serious infections.

How to manage the interaction:
Although taking Mertabto 10 Tablet and Clozapine together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor right away if you experience fever, chills, diarrhea, soreness, muscle aches, difficulty breathing, weight loss, or pain, burning sensation while urination. Do not stop using any medications without talking to a doctor.

MercaptopurineTeriflunomide

Severe

How does the drug interact with Mertabto 10 Tablet:
The combined use of Mertabto 10 Tablet with Teriflunomide can increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Mertabto 10 Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you notice any of these signs - fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, tiredness, feeling sick, vomiting, dark urine, or bleeding - contact your doctor right away. Do not discontinue any medications without consulting your doctor.

MercaptopurineTofacitinib

Severe

How does the drug interact with Mertabto 10 Tablet:
Taking Tofacitinib and Mertabto 10 Tablet increases the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Mertabto 10 Tablet and Tofacitinib, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
Drink plenty of water daily while taking Mertabto 10 Tablet as some cancer therapies may cause dehydration.
Exercise regularly and maintain a healthy body weight.
Regularly wash your hands and avoid contact with people having infections.
Quit smoking.

Side Effects of Mertabto 10 Tablet

Nausea
Vomiting
Low red blood cell count
Loss of appetite
Diarrhoea
Inflammation of the mouth

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Mertabto 10 Tablet Substitute

Captomac-10 Tablet 10's

by Others

₹4.35per tablet

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:37 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Mertabto 10 Tablet work?

Mertabto 10 Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Mertabto 10 Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Does Mertabto 10 Tablet affect fertility?

Mertabto 10 Tablet may affect eggs or cause low sperm count. Therefore, please consult a doctor before taking Mertabto 10 Tablet if you are planning to become parents.

Does Mertabto 10 Tablet increase sensitivity to sunlight?

Mertabto 10 Tablet may increase sensitivity to sunlight or UV light. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use a sunscreen before going out in the sun.

Does Mertabto 10 Tablet cause low blood sugar levels?

Mertabto 10 Tablet may cause low blood sugar levels in children below 6 years and those having low body weight. Therefore, use Mertabto 10 Tablet with caution in children and if you notice any symptoms such as dizziness, excessive sweating, confusion or nausea, please consult a doctor immediately.

Can a take vaccinations with Mertabto 10 Tablet ?

If you are about to receive any vaccinations especially live vaccines such as measles vaccine, flu vaccine, BCG vaccine, etc., it is advised to inform your doctor that you are on treatment with Mertabto 10 Tablet as it may cause infections.

Does Mertabto 10 Tablet cause infections?

Mertabto 10 Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any signs of infection such as urinary problems, chills, fever, cough, sore throat or mouth and avoid contact with people having cold, flu or infection.

Drug-Drug Interactions Checker List

FEBUXOSTAT
ALLOPURINOL
MESALAZINE
SULFASALAZINE
WARFARIN
ACENOCOUMAROL
INFLIXIMAB
PHENYTOIN
CARBAMAZEPINE
RIBAVIRIN
THIOPURINOL
OXIPURINOL
OLSALAZINE

Special Advise

Regular blood and urine tests are recommended while taking Mertabto 10 Tablet to monitor the number of red blood cells, platelets, white blood cells, uric acid levels, kidney or liver functioning.
Do not receive any vaccination during treatment without your doctor's approval while taking Mertabto 10 Tablet .

Disease/Condition Glossary

Blood cancer: It is the cancer of blood cells, also known as leukaemia. It causes excessive production of immature white blood cells by the bone marrow. The symptoms include unintentional weight loss, weakness, excessive sweating, tiredness, bone pain, frequent infections, chills or fever, red spots on the skin or painless, swollen lymph nodes, especially in the armpits neck. The risk factors of leukaemia include smoking, genetic or blood disorders, family history of leukaemia, exposure to high radiation levels, or previous cancer treatment with radiation or chemotherapy.