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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Synonym :

S METOPROLOL+HYDROCHLOROTHIAZIDE

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Met XL H 50 Tablet

Met XL H 50 Tablet belongs to the class of anti-hypertensives, primarily taken to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. Met XL H 50 Tablet is a combination medication generally used when a single medicine is unable to control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Met XL H 50 Tablet is a combination of two medicines: Metoprolol and Hydrochlorothiazide. Metoprolol belongs to the class of drugs known as β-blockers that works by relaxing the blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Met XL H 50 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. This medicine needs to be taken regularly to be effective.

Take Met XL H 50 Tablet as prescribed by your doctor. Depending on your medical conditions, you are advised to take Met XL H 50 Tablet for as long as your doctor has prescribed it for you. You may experience nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in blood. Most of these side effects of Met XL H 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Met XL H 50 Tablet , have liver disease, kidney disease, asthma, heart failure, a heart valve problem, or have a history of a heart attack. Pregnant and breastfeeding women should consult their doctor before taking Met XL H 50 Tablet . Orthostatic hypotension (sudden lowering of blood pressure) might occur, so patients taking Met XL H 50 Tablet should get up with caution. A prolonged intake of Met XL H 50 Tablet may decrease your blood potassium levels. So, it is better to ask your doctor about foods high in potassium, like bananas or orange juice. Regular monitoring of blood pressure, kidney function, and electrolyte (sodium, potassium, calcium, etc.) are recommended while taking Met XL H 50 Tablet . And also, a healthy diet and regular exercise are necessary to keep blood pressure under control.

Uses of Met XL H 50 Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Met XL H 50 Tablet contains a combination of medicines: Metoprolol (beta-blockers) and Hydrochlorothiazide (thiazide diuretic or water pill). Metoprolol plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in our bodies. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Collectively, both help reduces blood pressure and the chance of a stroke, heart attack, and oedema (fluid overload).

Storage

Keep Met XL H 50 Tablet out of the sight and reach of children.

Drug Warnings

Don't stop taking Met XL H 50 Tablet without talking to your doctor first. Stopping Met XL H 50 Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Met XL H 50 Tablet if you have allergic to Met XL H 50 Tablet , have low blood pressure (less than 90 mm of Hg), very slow heartbeat, serious lung condition (like asthma), serious heart condition (sick sinus syndrome), or any heart blockage. Do not use Met XL H 50 Tablet if you are pregnant, planning for pregnancy, breastfeeding, or unable to urinate (anuria). It should not be given to the children as safety and effectiveness have not been established. Before taking Met XL H 50 Tablet you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), eye problem (glaucoma), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud’s syndrome). You should monitor your blood pressure regularly to make sure the Met XL H 50 Tablet is working efficiently. Besides this, prolonged intake of Met XL H 50 Tablet can lead to lowering of blood pressure (hypotension). So, daily monitoring of blood pressure is advisable.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Met XL H 50 Tablet:
Taking Dofetilide and Met XL H 50 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Met XL H 50 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Met XL H 50 Tablet:
Taking Cisapride and Met XL H 50 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Met XL H 50 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Met XL H 50 Tablet:
Use of Met XL H 50 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Met XL H 50 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Met XL H 50 Tablet:
Taking ceritinib together with Met XL H 50 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Met XL H 50 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Met XL H 50 Tablet:
Coadministration of Acebutolol with Met XL H 50 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Met XL H 50 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Met XL H 50 Tablet:
Coadministration of Met XL H 50 Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Met XL H 50 Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Met XL H 50 Tablet:
Both Met XL H 50 Tablet and Artemether may increase the blood levels and effects of Met XL H 50 Tablet activity.

How to manage the interaction:
Taking Met XL H 50 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Met XL H 50 Tablet:
Co-administration of Clonidine and Met XL H 50 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Met XL H 50 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Met XL H 50 Tablet:
Coadministration of Met XL H 50 Tablet and Tizanidine may reduce the efficiency of Met XL H 50 Tablet.

How to manage the interaction:
Taking Met XL H 50 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Met XL H 50 Tablet:
Taking elvitegravir may increase the metabolism of Met XL H 50 Tablet.

How to manage the interaction:
Although there may be an interaction, Met XL H 50 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Side Effects of Met XL H 50 Tablet

  • Nausea
  • Fatigue
  • Headache
  • Dizziness
  • Diarrhoea
  • Stuffy nose, sore throat
  • Slow heart rate
  • Increased blood uric acid
  • Decreased potassium/ magnesium level in the blood
  • Increased calcium level in the blood
  • Altered blood lipid level
  • Glucose intolerance

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • ACEBUTOLOL
  • ATENOLOL
  • BISOPROLOL
  • CARTEOLOL
  • ESMOLOL
  • NADOLOL
  • LISINOPRIL
  • ENALAPRIL
  • DILTIAZEM
  • PRAZOSIN
  • TERAZOSIN
  • RAMIPRIL
  • ATORVASTATIN
  • FUROSEMIDE
  • CHLOROTHIAZIDE
  • CHLORTHALIDONE
  • INDAPAMIDE
  • METOLAZONE
  • THEOPHYLLINE
  • AMINOPHYLLINE
  • IBUPROFEN
  • ASPIRIN
  • TERBINAFINE
  • ALDESLEUKIN
  • DIPYRIDAMOLE
  • RIFAMPICIN
  • RITONAVIR
  • DIPHENHYDRAMINE
  • AMIODARONE
  • PROPAFENONE
  • QUINIDINE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • FLECAINIDE
  • DIGOXIN
  • LIDOCAINE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

Have a query?

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Alcohol

Caution

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with Met XL H 50 Tablet

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Pregnancy

Caution

Met XL H 50 Tablet is a pregnancy category C drug. It is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Small amounts of Met XL H 50 Tablet passes into the breast milk. However which is not enough to cause any problems to your baby. But, still, it is advisable to contact your doctor before breastfeeding your baby.

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Driving

Caution

You may experience dizziness, tiredness, or blurred vision while taking Met XL H 50 Tablet . So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Caution

Met XL H 50 Tablet should be used with caution in patients with impaired hepatic function or progressive liver disease since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Met XL H 50 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

The safety and efficacy of Met XL H 50 Tablet in children have not been established. Met XL H 50 Tablet is not recommended in children.

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