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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
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Composition :

METHIMAZOLE-10MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Methimez 10 Tablet

Methimez 10 Tablet belongs to the class of ‘anti-thyroid agents,’ primarily used to treat an overactive thyroid (hyperthyroidism) and Graves disease. Methimez 10 Tablet is also used before thyroid surgery and radioactive iodine treatment. Hyperthyroidism is a condition associated with too much production of a hormone called thyroxine by the thyroid gland. The thyroid gland is a butterfly-shaped endocrine gland located in the base of your neck. Graves disease is an autoimmune disorder that causes hyperthyroidism.

Methimez 10 Tablet contains ‘Methimazole’ that belongs to the class of ‘Anti-thyroid agents’. It is considered a first-line medicine for treating hyperthyroidism and Graves disease. Methimez 10 Tablet works by reducing the excessive production of thyroid hormones from the thyroid gland, thereby preventing hyperthyroidism symptoms.

Your doctor will advise the appropriate dose that suits your medical condition. Common side effects of Methimez 10 Tablet include headache, stomach upset, nausea, vomiting and mild skin rash or itching. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor’s advice.

Let your doctor know if you are sensitive to Methimez 10 Tablet or any other medications. Before using Methimez 10 Tablet , let your doctor know if you have liver, kidney or heart diseases, blood disorders and any other medical history. Methimez 10 Tablet is not recommended during the first three months of pregnancy. Methimez 10 Tablet passes into the breast milk. It is advised that pregnant and breastfeeding women should consult their doctor before using Methimez 10 Tablet . Methimez 10 Tablet is recommended for use in children only with a doctor’s advice.

Uses of Methimez 10 Tablet

Hyperthyroidism and Graves disease.

Directions for Use

Swallow the tablet with or without food, followed by a glass of water. Do not chew, crush or break it. Take Methimez 10 Tablet at a fixed time.

Medicinal Benefits

Methimez 10 Tablet is an ‘anti-thyroid agent’, containing ‘Methimazole’. It is used to treat an overactive thyroid (hyperthyroidism) and Graves disease. Methimez 10 Tablet is also used before thyroid surgery and radioactive iodine treatment. It treats hyperthyroidism by inhibiting the synthesis of thyroid hormones from the thyroid gland. Methimez 10 Tablet is also used in patients with toxic multinodular goitre (an enlarged thyroid gland that contains masses called nodules with hypothyroidism symptoms) for whom surgery and radioactive iodine treatments are not an option. It also relieves hypothyroidism symptoms in preparation for thyroidectomy (surgical removal of whole or part of the thyroid gland) or radioactive iodine therapy. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Let your doctor know if you are sensitive to Methimez 10 Tablet or any other medications. Before using Methimez 10 Tablet , let your doctor know if you have any medical history of liver or kidney diseases, congenital disorders (birth defects), hypothyroidism (low levels of thyroid hormones), blood disorders like agranulocytosis (lowered white blood cell count) and thrombocytopenia (low levels of platelets) and pancreatitis (inflammation of the pancreas, an organ behind the stomach). Please inform your doctor if you have any scheduled surgery while using Methimez 10 Tablet . Pregnant and breastfeeding women should consult their doctor before starting Methimez 10 Tablet . You may feel sleepy or dizzy while using Methimez 10 Tablet , hence do not drive or operate machinery until you are mentally alert. Limit your alcohol consumption during a course with Methimez 10 Tablet . Methimez 10 Tablet is recommended for use in children only with a doctor’s advice.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Methimez 10 Tablet:
Taking Methimez 10 Tablet with Deferiprone may increase the risk of severe infections.

How to manage the interaction:
Taking Methimez 10 Tablet with Deferiprone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination - contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Methimez 10 Tablet:
When Clozapine is taken with Methimez 10 Tablet, the effects of Clozapine increases.

How to manage the interaction:
There may be a possibility of interaction between Methimez 10 Tablet and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms - feeling weak, having a sore throat, fever, mouth sores, feeling tired or having flu-like symptoms, contact a doctor right away. Do not stop using any medications without a doctor's advice.
MethimazoleLomitapide
Severe
How does the drug interact with Methimez 10 Tablet:
Taking Lomitapide and Methimez 10 Tablet together can increase the risk of liver problems.

How to manage the interaction:
Although taking Methimez 10 Tablet and Lomitapide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
How does the drug interact with Methimez 10 Tablet:
Taking Propylthiouracil with Methimez 10 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Propylthiouracil with Methimez 10 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MethimazoleMipomersen
Severe
How does the drug interact with Methimez 10 Tablet:
The combined use of Mipomersen and Methimez 10 Tablet together can increase the liver problems.

How to manage the interaction:
Although there is a possible interaction between Methimez 10 Tablet and Mipomersen, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without talking to a doctor.
How does the drug interact with Methimez 10 Tablet:
The combined use of Methimez 10 Tablet with Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking Methimez 10 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Methimez 10 Tablet:
Co-administration of Fluphenazine and Methimez 10 Tablet together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methimez 10 Tablet and Fluphenazine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Methimez 10 Tablet for more than once per day. Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Eat at regular intervals.
  • Follow a low-sodium diet by limiting iodized salt, seafood, dairy products, high amounts of poultry or beef, high amounts of grain products like bread, pasta and pastries and egg yolks.

Habit Forming

No

Therapeutic Class

THYROID AND ANTITHYROID AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Methimez 10 Tablet consists of Methimazole, an anti-thyroid agent. It treats overactive thyroid (hyperthyroidism) and Graves disease by inhibiting the synthesis of thyroid hormones by the thyroid gland. Thus Methimez 10 Tablet effectively helps in treating hyperthyroidism and relieving its symptoms.

Methimez 10 Tablet should be used with caution and only under doctor’s supervision if you have a medical history of liver or kidney diseases, congenital disorders (birth defects), hypothyroidism (low levels of thyroid hormones), blood disorders like agranulocytosis (lowered white blood cell count) and thrombocytopenia (low levels of platelets) and pancreatitis (inflammation of the pancreas, an organ behind the stomach).

Sometimes, Methimez 10 Tablet may cause hypoprothrombinemia (deficiency of the blood-clotting substance, prothrombin) and lead to bleeding. Hence, your doctor may advise test for prothrombin time before surgery while undergoing treatment with Methimez 10 Tablet . Please seek medical advice for more information.

It is advised to regularly monitor your thyroid hormone levels with thyroid function tests while using Methimez 10 Tablet . If there is clinical evidence of rising serum thyroid levels, your doctor may lower the dose of Methimez 10 Tablet .

If you missed a dose, take Methimez 10 Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • WARFARIN
  • DIGOXIN
  • THEOPHYLLINE
  • METOPROLOL
  • ATENOLOL
  • CARVEDILOL
  • LABETALOL
  • NADOLOL
  • PROPRANOLOL
  • SOTALOL

Special Advise

  • It is advised to monitor your blood pressure and blood glucose levels regularly while using Methimez 10 Tablet .
  • Regular monitoring of thyroid levels with T3, T4 and TSH (thyroid-stimulating hormone) tests is recommended.
  • Regular monitor of liver functioning is recommended with liver function tests is recommended during Methimez 10 Tablet usage.
  • Methimez 10 Tablet may cause hypoprothrombinemia (deficiency of the blood-clotting substance, prothrombin) and lead to bleeding. Hence, your doctor may advise test for prothrombin time before surgery while undergoing treatment with Methimez 10 Tablet .

Disease/Condition Glossary

Hyperthyroidism: It is a condition associated with too much production of a hormone called thyroxine by the thyroid gland. The thyroid gland is a butterfly-shaped endocrine gland located in the base of your neck. Symptoms of an overactive thyroid include unexpected weight loss, rapid or irregular heartbeat, sweating, irritability, mood swings, weakness, sleep problems, thinning of the skin and changes in the menstrual cycle. If left untreated, hyperthyroidism can cause heart, bones, muscles, menstrual cycle and fertility problems. It is considered that women are 2 to 10 times more likely than men to develop this disease.

Grave's disease: It is an autoimmune disorder that causes hyperthyroidism. It is considered to be the primary cause of hyperthyroidism. It usually affects women under the age of 40.

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