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Synonym :

S AMLODIPINE+S METOPROLOL SUCCINATE

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metpure AM 2.5 Tablet

Metpure AM 2.5 Tablet belongs to a class of medication called anti-hypertensive agents primarily used to treat hypertension (high blood pressure). Also, Metpure AM 2.5 Tablet is used to treat chest pain, irregular heart rhythm. Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Metpure AM 2.5 Tablet is a combination of two drugs, namely:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class that works by blocking beta receptors in the heart and makes the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together they lower high blood pressure.

Take Metpure AM 2.5 Tablet as prescribed by your doctor. You are advised to take Metpure AM 2.5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention. Most of these side effects of Metpure AM 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert as Metpure AM 2.5 Tablet may cause dizziness or tiredness. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Metpure AM 2.5 Tablet is used with caution in heart failure, during surgeries, pheochromocytoma, lung diseases, diabetes, peripheral vascular disease, hyperthyroidism, aortic stenosis. Metpure AM 2.5 Tablet is not recommended in cardiogenic shock, hyperlipidemia, glaucoma, liver diseases.

Uses of Metpure AM 2.5 Tablet

Hypertension (high blood pressure), angina (chest pain)

Directions for Use

Take Metpure AM 2.5 Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Metpure AM 2.5 Tablet contains S-amlodipine and S-metoprolol primarily used to treat high blood pressure. S-amlodipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to beta-blockers that block beta receptors in the heart and make the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metpure AM 2.5 Tablet

  • Tiredness
  •  Dizziness
  •  Slow heart rate
  •  Nausea
  •  Headache
  •  Orthostatic hypotension (low blood pressure when standing up from sitting or lying position)
  •  Depression
  •  Stomach pain
  •  Fluid retention

Drug Warnings

If you are known to be allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Complete the full course of medication and do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Avoid taking Metpure AM 2.5 Tablet if you have blood circulation or heart problems, Prinzmetal’s angina (painful feeling in the chest in periods of rest), asthma, chronic obstructive pulmonary disease (COPD), breathing problems, phaeochromocytoma (tumor in the adrenal gland), low blood pressure, diabetes or metabolic acidosis (increased acidity of the blood), hyperthyroidism. Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert as Metpure AM 2.5 Tablet may cause dizziness or tiredness. If you are about to under any surgery or receive anesthetics, please inform your doctor or dentist that you are taking Metpure AM 2.5 Tablet as it may cause a very slow heartbeat.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
MetoprololSaquinavir
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Metpure AM 2.5 Tablet:
Using Metpure AM 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Metpure AM 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
MetoprololSaquinavir
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Using Metpure AM 2.5 Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metpure AM 2.5 Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Acebutolol with Metpure AM 2.5 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololVerapamil
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Metpure AM 2.5 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololClonidine
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Co-administration of Clonidine and Metpure AM 2.5 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure AM 2.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Taking elvitegravir may increase the metabolism of Metpure AM 2.5 Tablet.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololArtemether
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Both Metpure AM 2.5 Tablet and Artemether may increase the blood levels and effects of Metpure AM 2.5 Tablet activity.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Combine use of Metpure AM 2.5 Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololAtazanavir
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Use of Metpure AM 2.5 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metpure AM 2.5 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololCeritinib
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Taking ceritinib together with Metpure AM 2.5 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Metpure AM 2.5 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine and Metoprolol. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, which may lower high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Metpure AM 2.5 Tablet Substitute

Substitutes safety advice
  • Eslomet 2.5 Tablet 10's

    by Others

    12.60per tablet
  • STARCAD SA 2.5MG TABLET

    by Others

    7.65per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Metpure AM 2.5 Tablet is a combination of two drugs, namely:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class that works by blocking beta receptors in the heart and makes the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together they lower high blood pressure.

Metpure AM 2.5 Tablet cause common side effects like tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention.

Metpure AM 2.5 Tablet should be used with caution in diabetic patients as it may increase the risk of severe low blood sugar levels. Therefore, if you have diabetes, inform your doctor before taking Metpure AM 2.5 Tablet . Also, regular monitoring of blood sugar levels is recommended while taking Metpure AM 2.5 Tablet .

Metpure AM 2.5 Tablet may cause dizziness when standing up from sitting or lying position suddenly. Therefore, to avoid such effects, it is advised to stand up slowly from sitting or lying position.

Metpure AM 2.5 Tablet may cause high potassium levels in the blood and cause adverse effects on overdose. Therefore, take Metpure AM 2.5 Tablet only in doses as prescribed by your doctor.

Metpure AM 2.5 Tablet is may be safe to use in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • DULOXETINE
  • NEFAZODONE
  • FUROSEMIDE
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • VERAMAPIL
  • DILTIAZEM
  • NIFEDIPINE
  • DISOPYRAMIDE
  • QUINIDINE
  • AMIODARONE
  • PROPAFENONE
  • INSULIN GLARGINE
  • LEVOTHYROXINE
  • ALPRAZOLAM
  • APIXABAN
  • ATORVASTATIN

Special Advise

  • Regular monitoring of blood pressure is recommended while taking Metpure AM 2.5 Tablet .
  • Metpure AM 2.5 Tablet may rarely cause changes in blood tests and liver function tests.
  • A low salt diet and regular exercise are recommended along with Metpure AM 2.5 Tablet for effective results.
  • Your doctor may advise regular blood tests for monitoring of electrolytes.

Disease/Condition Glossary

Blood pressure/Hypertension: Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.

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