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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metpure IR 25 mg Tablet

Metpure IR 25 mg Tablet belongs to a group of medicines called “Antihypertensive” used alone or together with other medicines to treat high blood pressure (hypertension), heart-related chest pain (angina), and heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches. High blood pressure adds to the workload of the heart and arteries. Hypertension or high blood pressure is a long-term force of the blood against the arteries that may lead to various types of heart diseases. If it continues for a long time, it can damage the blood vessels (arteries) of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure reduces the risk of stroke, heart attack, and heart-related chest pain (angina).

Metpure IR 25 mg Tablet contains S Metoprolol Succinate. It plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body. This lowers your blood pressure and helps reduce your risk of a stroke, a heart attack, other heart problems, or kidney problems in the future. Metpure IR 25 mg Tablet needs to be taken regularly to be effective.

Metpure IR 25 mg Tablet should be taken in the dose and duration your doctor advises. You are advised to take Metpure IR 25 mg Tablet for as long as your doctor has prescribed, depending on your medical condition. In some cases, you may experience common side effects such as headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities. Most of these side effects of Metpure IR 25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. However, you are advised to talk to your doctor if you experience these side effects persistently.

Don't stop taking Metpure IR 25 mg Tablet without consulting your doctor first. Stopping Metpure IR 25 mg Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose over time to help prevent these symptoms. Metpure IR 25 mg Tablet should not be used to prevent heart attacks. You should not use Metpure IR 25 mg Tablet if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. Pregnant and breastfeeding women should consult the doctor before taking the Metpure IR 25 mg Tablet . Driving and operating heavy machinery should not be done as it may cause dizziness and drowsiness.  Orthostatic hypotension (sudden lowering of blood pressure n standing) might occur, so patients using Metpure IR 25 mg Tablet should get up with caution. Metpure IR 25 mg Tablet is contraindicated if you have high amounts of potassium in your blood (shown in blood test results). Metpure IR 25 mg Tablet may affect your ability to drive or operate heavy machinery if taken with alcohol. 

Uses of Metpure IR 25 mg Tablet

Hypertension (high blood pressure), Angina (heart-related chest pain), Arrhythmia (heart rhythm disorder), Heart failure, Stroke, Migraine.

Directions for Use

Swallow the tablet with a glass of water as a whole. Do not crush, break, or chew the tablet. Metpure IR 25 mg Tablet can be taken with or without food. Take Metpure IR 25 mg Tablet as prescribed by your doctor. Metpure IR 25 mg Tablet should not be taken unless prescribed by a doctor. Based on your medical condition, your doctor will advise how long you need to take Metpure IR 25 mg Tablet .

Medicinal Benefits

Metpure IR 25 mg Tablet contains S Metoprolol Succinate belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it also helps relieve symptoms of migraine-related headaches. Metpure IR 25 mg Tablet  helps slow down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Metpure IR 25 mg Tablet if you are allergic (hypersensitive) to the Metpure IR 25 mg Tablet or any ingredients present. Please consult your doctor before taking Metpure IR 25 mg Tablet if you are pregnant or planning to conceive and breastfeed. It should not be given to children less than 12 years of age. Don't stop taking Metpure IR 25 mg Tablet without talking to your doctor first. Stopping Metpure IR 25 mg Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over some time to help prevent these symptoms. You should not use the Metpure IR 25 mg Tablet if you have a very slow heartbeat, a serious lung condition (like asthma), a serious heart condition (sick sinus syndrome), or a heart blockage. Before taking this medicine, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud's syndrome).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Metpure IR 25 mg Tablet:
Co-administration of Clonidine and Metpure IR 25 mg Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure IR 25 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Metpure IR 25 mg Tablet:
Both Metpure IR 25 mg Tablet and Artemether may increase the blood levels and effects of Metpure IR 25 mg Tablet activity.

How to manage the interaction:
Taking Metpure IR 25 mg Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure IR 25 mg Tablet:
Coadministration of Aminophylline with Metpure IR 25 mg Tablet together can make Metpure IR 25 mg Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metpure IR 25 mg Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure IR 25 mg Tablet:
Coadministration of Metpure IR 25 mg Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure IR 25 mg Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Metpure IR 25 mg Tablet:
Combine use of Metpure IR 25 mg Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Metpure IR 25 mg Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololAcebutolol
Severe
How does the drug interact with Metpure IR 25 mg Tablet:
Coadministration of Acebutolol with Metpure IR 25 mg Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metpure IR 25 mg Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure IR 25 mg Tablet:
Use of Metpure IR 25 mg Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metpure IR 25 mg Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure IR 25 mg Tablet:
Coadministration of Metpure IR 25 mg Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Metpure IR 25 mg Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololSaquinavir
Severe
How does the drug interact with Metpure IR 25 mg Tablet:
Using Metpure IR 25 mg Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metpure IR 25 mg Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metpure IR 25 mg Tablet:
Taking elvitegravir may increase the metabolism of Metpure IR 25 mg Tablet.

How to manage the interaction:
Although there may be an interaction, Metpure IR 25 mg Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
  • Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Metpure IR 25 mg Tablet contains S Metoprolol Succinate, which helps to reduce blood pressure by allowing the blood to flow more smoothly. It is an extended-release medication, its active ingredient is released slowly over time into the body, so you will typically only need to take the Metpure IR 25 mg Tablet once a day.

Use of Metpure IR 25 mg Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are a diabetic patient, always consult a doctor before taking Metpure IR 25 mg Tablet .

Serum sodium, serum potassium, white blood cells, and kidney or renal function should be closely monitored before taking Metpure IR 25 mg Tablet .

Serum sodium, potassium, white blood cells, and kidney or renal function should all be properly evaluated before taking Metpure IR 25 mg Tablet .

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Metpure IR 25 mg Tablet can increase blood potassium levels. So a potassium-rich diet and supplements should be avoided while taking Metpure IR 25 mg Tablet to avoid any unpleasant side effects.

Drug-Drug Interactions Checker List

  • CLONIDINE
  • DILTIAZEM
  • CERITINIB
  • DOLASETRON
  • DISOPYRAMIDE
  • VERAPAMIL
  • FEXINIDAZOLE
  • FINGOLIMOD
  • SIPONIMOD
  • TIZANIDINE
  • ATAZANAVIR
  • SAQUINAVIR
  • HOUSE DUST MITE ALLERGEN EXTRACT
  • MIXED GRASS POLLENS ALLERGEN EXTRACT
  • PEANUT ALLERGEN POWDER
  • RAGWEED POLLEN ALLERGEN EXTRACT
  • TIMOTHY GRASS POLLEN ALLERGEN EXTRACT
  • METHACHOLINE
  • OXTRIPHYLLINE
  • RITODRINE
  • THEOPHYLLINE
  • AMINOPHYLLINE
  • DYPHYLLINE

Special Advise

  • Metpure IR 25 mg Tablet can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
  • Do not stop taking Metpure IR 25 mg Tablet suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Disease/Condition Glossary

Hypertension: High blood pressure is a chronic condition when the blood pressure and the heart's workload are too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm and 120/80 mm Hg.

Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.

Arrhythmia: Arrhythmia is a condition with the rate at which the heart beats. In this condition, the heart beats too quickly, too slowly, or at an irregular rate. It can cause significant heart damage. A cardiac arrhythmia develops when there are irregular electrical signals in the heart. Tachycardia occurs when the heart beats too quickly, while bradycardia occurs when it beats too slowly. Arrhythmia treatment involves medicines, medical treatments, implanted devices, and, in certain cases, surgery.

Heart failure: Heart failure is a chronic disorder in which the heart's ability to pump blood is impaired. Heart failure can arise as a result of disorders such as excessive blood pressure, heart muscle enlargement or injury, defective heart valves, or restricted arteries in the heart. Shortness of breath, weariness, a rapid heartbeat, and swelling legs are all symptoms of heart failure.

Stroke: A stroke is a potentially fatal medical illness that occurs when the blood flow to a portion of the brain is cut off. Strokes are medical emergency that requires immediate treatment. The brain, like all organs, needs the oxygen and nutrients delivered by the blood to function correctly. Brain cells begin to die when the blood supply is reduced or terminated. This can result in brain injury, incapacity, and even death.

Migraine: A migraine headache is typically characterised by intense pain on one side of the brain. Many patients also have symptoms such as nausea, vomiting, and heightened sensitivity to light or sound. Some people suffer from migraines on a regular basis, up to several times per week. Others only get migraines on occasion. It is possible to go years without having a migraine attack. Migraines can have a negative impact on your quality of life and prevent you from carrying out your typical daily activities.

 

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