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Reviewed By Sunny S , MBBS
Non returnable*
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Metrogyl O Tablet

Metrogyl O Tablet is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) used to treat various infections caused by bacteria and dysentery caused due to amoeba. A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. It can target any body part and multiple very quickly. Amoebic dysentery can be caused due to Entamoeba histolytica, Giardia lamblia, or Clostridium difficile.

Metrogyl O Tablet is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Both are bactericidal in nature, and collectively they help in treating the disease effectively.

Take Metrogyl O Tablet as prescribed. Your doctor will recommend how often you take Metrogyl O Tablet based on your medical condition. In some cases, you may experience nausea, vomiting, upset of stomach, loss of appetite, dry mouth, and metallic taste. Metronidazole can also cause headache, dizziness, drowsiness, and confusion. Most of these side effects of Metrogyl O Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, shortness of breath, etc., please consult your doctor immediately.

It is not advisable to stop taking Metrogyl O Tablet suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed. Inform your doctor if you have any lung disease, epilepsy, sleeping disorder, or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Metrogyl O Tablet should not be used by the pregnant women (especially during the first trimester), breastfeeding mother and patients with liver diseases, low blood white cells (leukopenia), seizures (fits), gastro intestine diseases (like Crohn's disease, Inflammatory bowel disease etc.) and other neurological related diseases. Do not drive or operate heavy machinery as it can lower your mental alertness and cause dizziness.

Uses of Metrogyl O Tablet

Bacterial infection, Diarrhea, Dysentry, Intestinal infection

Directions for Use

Tablet: Take it with or without food (excluding dairy products) as advised by the doctor. Swallow it with a glass of water. Do not break, crush or chew it.Suspension: Shake the bottle well before use. Check the label for directions and take it with or without food in doses as prescribed by the doctor with the help of a measuring cup.

Medicinal Benefits

Metrogyl O Tablet is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Metronidazole kills parasites and bacteria that are responsible for causing infections. It works by damaging their DNA. Both are bactericidal in nature.

Storage

Keep Metrogyl O Tablet out of the sight and reach of children.
Side effects of Metrogyl O Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear cotton underwear and loose pants to facilitate better airflow.
  • Try meditation and yoga to reduce stress and improve balance hormones.
  • Eat foods like yogurt or kefir to support vaginal health.
  • Gently clean the genital area with soap and lukewarm water.
  • Avoid fragrant soap, bubble baths, and douches; these can also irritate.
  • Tell your doctor about any medications or supplements you’re taking, as they may affect vaginal discharge treatments.

Drug Warnings

If you are allergic to ofloxacin, metronidazole, or any other antibacterial or anti-amoebic agents, please inform your doctor to avoid any unwanted side effects like swallowing or breathing problems, swelling of your lips, face, throat, or tongue. Taking Metrogyl O Tablet may increase the chances of developing tendinitis (swelling of a tissue that joins a bone to a muscle) or a tendon rupture. Dairy products should be avoided along with Metrogyl O Tablet. And also, exposure to sunlight should be avoided while taking Metrogyl O Tablet as it may cause increased phototoxicity or photosensitivity. Patients with an irregular heartbeat (QT prolongation) should tell their doctor before taking Metrogyl O Tablet. Some medicines like pain killers (ibuprofen or diclofenac,) anti-asthma (theophylline), anti-diabetic (glibenclamide), anti-gout (probenecid), anti-cancer (5-fluorouracil), antidepressant (lithium), antiepileptic (phenobarbital, phenytoin), blood thinner (warfarin) should not be taken with Metrogyl O Tablet to avoid worsening of the condition. Metrogyl O Tablet should not be given to the pregnant mother (during the first trimester) and in nursing mothers as it passes into the breast milk. Please inform you, doctor, before taking Metrogyl O Tablet if you have a history of problems with your liver, blood, low white blood cell count (leukopenia), nervous system (convulsions). Do not drink alcohol with Metrogyl O Tablet as it may cause flushing and drowsiness which can alter your mental alertness.

Drug-Drug Interactions

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OfloxacinQuinidine
Critical
OfloxacinHalofantrine
Critical

Drug-Drug Interactions

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OfloxacinQuinidine
Critical
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Metrogyl O Tablet:
Using halofantrine together with Metrogyl O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Metrogyl O Tablet with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Metrogyl O Tablet with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinBepridil
Critical
How does the drug interact with Metrogyl O Tablet:
Using bepridil together with Metrogyl O Tablet drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Metrogyl O Tablet with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Metrogyl O Tablet:
Using Mesoridazine together with Metrogyl O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Metrogyl O Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metrogyl O Tablet:
Coadministration of Metrogyl O Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Metrogyl O Tablet with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Metrogyl O Tablet may increase nervousness, sleeplessness, and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Metrogyl O Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Metrogyl O Tablet.
  • Avoid intake of alcoholic beverages with Metrogyl O Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Metrogyl O Tablet in fighting off infections.

Side Effects of Metrogyl O Tablet

  • Nausea
  • Vomiting
  • Upset stomach
  • Loss of appetite
  • Dry mouth
  • Metallic taste
  • Headache

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Metrogyl O Tablet Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

It is not advised to take alcohol with Metrogyl O Tablet. Taking alcohol while taking Metrogyl O Tablet can cause serious side effects such as headaches, feeling or being sick, pain in the stomach, hot flushes, a fast or irregular heartbeat, dizziness, drowsiness, etc.

Metrogyl O Tablet makes your skin sensitive to sunlight, known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

If you miss a dose of Metrogyl O Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

No. Metrogyl O Tablet is an antibacterial medicine that acts only against bacterial infections and not against viral infections . You should not take Metrogyl O Tablet without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of Metrogyl O Tablet, leading to antibiotic resistance.

Yes, intake of Metrogyl O Tablet may cause dry mouth and you might be feeling thirsty frequently. Try to drink plenty of fluids (water with electrolytes) and probiotics. You may also have a dry lip for which you can use lip balm.

Avoid intake of Metrogyl O Tablet if you have a history of problems with your liver, blood or nervous system (convulsions or fits), low white blood cell count (leukopenia).

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • DICLOFENAC
  • THEOPHYLLINE
  • GLIBENCLAMIDE
  • PROBENECID
  • LITHIUM
  • PHENOBARBITAL
  • PHENYTOIN
  • WARFARIN

Special Advise

You should consult a doctor if you have symptoms associated with dehydration like dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness.

Disease/Condition Glossary

Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

Diarrhoea: It is the increase in bowel movement leading to increased and loose motions. 

Dysentery: It is inflammation of the intestine, particularly the colon, caused by the bacteria Shigella.

Have a query?

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Alcohol

Unsafe

Alcohol should not be consumed while taking Metrogyl O Tablet to avoid unpleasant side-effects like flushing, lightheadedness, dizzy and drowsy.

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Pregnancy

Unsafe

Metrogyl O Tablet should not be taken if you are pregnant or planning to have a baby. If you become pregnant while taking Metrogyl O Tablet, stop taking the medication, and contact your doctor immediately. Metronidazole should not be given in the first trimester of the pregnancy as it may cause harm to the fetus.

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Breast Feeding

Caution

Metrogyl O Tablet passes in the breast milk so the nursing mother should avoid taking Metrogyl O Tablet.

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Driving

Caution

Metrogyl O Tablet can cause dizziness in some patients. If you feel dizzy, please do not operate the car.

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Liver

Caution

Metrogyl O Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Metrogyl O Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Metrogyl O Tablet can be given to the children for typhoid fever, diarrhoea, stomach infection, amoebiasis, abdominal infection, diarrhoea and intestinal infection.

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