Migraneck Tablet 10's is a combination medicine indicated to treat and prevent migraine. Migraneck Tablet 10's is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. Migraine is a neurological condition that is characterized by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.
 
Migraneck Tablet 10's is a combination of four drugs, namely: Ergotamine tartrate (ergot alkaloid), caffeine (methylxanthine), prochlorperazine maleate (anti-emetic) and paracetamol (analgesic). Ergotamine tartrate works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.
 
Take Migraneck Tablet 10's with or without food. Swallow Migraneck Tablet 10's as a whole with a glass of water; do not chew, or break the tablet. Take Migraneck Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Migraneck Tablet 10's contains paracetamol, do not take other medicines containing paracetamol along with Migraneck Tablet 10's. Do not take Migraneck Tablet 10's if you are pregnant or breastfeeding. Migraneck Tablet 10's causes drowsiness and dizziness, so drive with caution. Migraneck Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Migraneck Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects.

Migraneck Tablet 10's contains Ergotamine tartrate, caffeine, prochlorperazine maleate, and paracetamol. Migraneck Tablet 10's is used to treat and prevent migraines. Ergotamine tartrate is an ergot alkaloid that works by constricting blood vessels in the brain and altering blood flow patterns associated with headaches. Caffeine is a methylxanthine that increases the vasoconstriction effect (narrowing of blood vessels). Prochlorperazine maleate is an anti-emetic that prevents migraine-related nausea and vomiting by altering the effects of neurotransmitters. Paracetamol is an analgesic that prevents the release of prostaglandins, which cause pain. Migraneck Tablet 10's is used to relieve migraine symptoms and prevent the attack from worsening.

• Stomach upset
• Dizziness
• Dry mouth
• Constipation
• Insomnia (trouble sleeping)

Do not take Migraneck Tablet 10's if you are allergic to any of its contents; if you have/had heart problems, blood circulation problems, or if you are taking antibiotics, anti-fungal, anti-HIV, or other anti-migraine medicines. Migraneck Tablet 10's, when taken along with antibiotics, anti-fungal, and anti-HIV drugs, could lead to unpleasant side effects such as poor blood flow to hands, feet, or brain. Migraneck Tablet 10's contains paracetamol, do not take other medicines containing paracetamol along with Migraneck Tablet 10's. Inform your doctor before taking Migraneck Tablet 10's if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take Migraneck Tablet 10's if you are pregnant or breastfeeding. Migraneck Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Migraneck Tablet 10's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Migraneck Tablet 10's as it could lead to increased drowsiness. Do not take other NSAIDs for pain relief while taking Migraneck Tablet 10's unless prescribed. 

Drug-Drug Interactions: Migraneck Tablet 10's may have interaction with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole), and anti-HIV medicines (indinavir, nelfinavir, ritonavir), a decongestant (oxymetazoline), pain killers (acetaminophen, butalbital, fentanyl), anti-depressant (fluoxetine, duloxetine), anti-anxiety (diazepam, lorazepam, alprazolam), antacid (ranitidine), antihistamine (diphenhydramine), anti-convulsant (pregabalin), anti-hypertensive (metoprolol), bronchodilators (albuterol), anti-emetic (ondansetron).

Drug-Food Interactions: Avoid the consumption of alcohol, smoking, and caffeinated products. Do not consume grapefruit while taking Migraneck Tablet 10's.

Drug-Disease Interactions: Migraneck Tablet 10's may have interactions with high blood pressure, vasospastic reactions, heart problems, bipolar disorder, psychotic disorders, seizure disorders, gastroesophageal reflux disease, and liver or kidney problems.

• CLARITHROMYCIN
• ERYTHROMYCIN
• TROLEANDOMYCIN
• ITRACONAZOLE
• KETOCONAZOLE
• INDINAVIR
• NELFINAVIR
• RITONAVIR
• OXYMETAZOLINE
• ACETAMINOPHEN
• BUTALBITAL
• FENTANYL
• FLUOXETINE
• DULOXETINE
• DIAZEPAM
• LORAZEPAM
• ALPRAZOLAM
• RANITIDINE
• DIPHENHYDRAMINE
• PREGABALIN
• METOPROLOL
• ALBUTEROL
• ONDANSETRON

• Maintaining a healthy diet and exercising regularly helps improve overall health and boost self-esteem.
• Avoid bright lights, loud noise, and extreme temperatures.
• Perform meditation and yoga. This helps in relieving stress and provides relaxation.
• Follow a regular sleep pattern to improve the amount and quality of sleep you get.
• Massage your scalp to ease the pain.
• Lie down in a quiet, dark room.
• Place a cold cloth over your forehead or neck.
• Avoid smoking, alcohol, and caffeinated drinks. 
• Learn what triggers your migraine and try avoiding them.
• Stay hydrated. Drink plenty of fluids.
• Learn relaxation skills as they help in reducing stress.

Migraine: Migraine is a neurological condition that is characterized by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. A migraine headache is preceded by warning symptoms one or two days before the headache. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light.