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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

DESMOPRESSIN-0.1MG

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Minirin 0.1 Tablet

Minirin 0.1 Tablet is a hormone analogue that belongs to the class of ‘antihemophilic agents’ primarily used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination) polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).

Minirin 0.1 Tablet contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, Minirin 0.1 Tablet is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-haemophilic agent, Minirin 0.1 Tablet also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.

Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin 0.1 Tablet include headache, nausea, abdominal cramp, flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting Minirin 0.1 Tablet , let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using Minirin 0.1 Tablet , limit water and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using Minirin 0.1 Tablet . Do not take or stop this medicine, if the doctor did not advise you to do so.

Uses of Minirin 0.1 Tablet

Diabetes insipidus, Post-hypophysectomy polyuria (polydipsia), and Bedwetting.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Minirin 0.1 Tablet is a hormone analogue that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone, vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controls bedwetting in children. Being an anti-haemophilic agent, Minirin 0.1 Tablet also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Minirin 0.1 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.

Drug Warnings

Before starting Minirin 0.1 Tablet , let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin 0.1 Tablet , limit water and other fluids' intake since it may lead to electrolyte imbalance. Inform your doctor if you have any allergic reactions or lactose intolerance before using Minirin 0.1 Tablet . Please consult your doctor before starting Minirin 0.1 Tablet if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination. 

Drug-Drug Interactions

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DesmopressinCiclesonide
Critical
DesmopressinBumetanide
Critical

Drug-Drug Interactions

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DesmopressinCiclesonide
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Bumetanide and Minirin 0.1 Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Ciclesonide together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinBumetanide
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Bumetanide and Minirin 0.1 Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Bumetanide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinFludrocortisone
Critical
How does the drug interact with Minirin 0.1 Tablet:
Using Minirin 0.1 Tablet together with fludrocortisone may increase the risk of hyponatremia( a condition associated with low levels of salt in the blood).

How to manage the interaction:
Taking Minirin 0.1 Tablet with Fludrocortisone is not recommended, but it can be taken if prescribed by a doctor. However, if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination and sudden weight gain contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DesmopressinDexamethasone
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Minirin 0.1 Tablet with Dexamethasone may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexamethasone and Minirin 0.1 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DesmopressinFluticasone Propionate
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Minirin 0.1 Tablet together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
Coadministration of Minirin 0.1 Tablet and Fluticasone Propionate is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination and sudden weight gain contact doctor immediately. Do not discontinue any medications without consulting a doctor.
DesmopressinPrednisone
Critical
How does the drug interact with Minirin 0.1 Tablet:
Coadministration of Prednisone and Minirin 0.1 Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and prednisone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinBeclometasone
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Minirin 0.1 Tablet together with Beclomethasone may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Beclomethasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinFluticasone furoate
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Minirin 0.1 Tablet together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Fluticasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinCortisone
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Cortisone and Minirin 0.1 Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Cortisone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
DesmopressinTorasemide
Critical
How does the drug interact with Minirin 0.1 Tablet:
Co-administration of Torasemide can make Minirin 0.1 Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Minirin 0.1 Tablet and Torasemide together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Minirin 0.1 Tablet for more than once per day. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Minirin 0.1 Tablet .
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Eat at regular intervals.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.

Habit Forming

No

Therapeutic Class

ANTIHEMOPHILICS

Minirin 0.1 Tablet Substitute

Substitutes safety advice
  • D PRESSIN TABLET

    by Others

    32.31per tablet

Author Details

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Drug-Diseases Interactions

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DESMOPRESSIN-0.1MGOther disorders of kidney and ureter, not elsewhere classified
Severe

Drug-Diseases Interactions

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DESMOPRESSIN-0.1MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Minirin 0.1 Tablet:
Minirin 0.1 Tablet is not recommended for people with moderate to severe renal impairment (creatinine clearance less than 50 mL/min).

How to manage the interaction:
The use of Minirin 0.1 Tablet is contraindicated in patients with moderate to severe kidney impairment.

FAQs

Minirin 0.1 Tablet contains Desmopressin, a human-made form of vasopressin (antidiuretic hormone). When your body cannot produce enough vasopressin, Minirin 0.1 Tablet is used to replace it. It helps treat diabetes insipidus, post-hypophysectomy polyuria or polydipsia, and bedwetting by causing water reabsorption in the kidneys and reducing the amount of urine to be filled up in the bladder.

Minirin 0.1 Tablet does not cause weight gain. But it may cause fluid overload as a side effect by reducing the amount of fluid to be urinated. This fluid overload can result in weight gain.

Minirin 0.1 Tablet does not cure bedwetting, but it helps control bedwetting. It is usually prescribed at the night time to prevent frequent urination.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Optimal intake of fluids is recommended. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks, leading to worsening of electrolyte imbalance.

Drug-Drug Interactions Checker List

  • LAMOTRIGINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • FUROSEMIDE

Special Advise

  • Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.
  • If you are frequently urinating, it is advised to consult your endocrinologist to check for any hormonal abnormalities.
  • You may also be advised for any CT, or MRI scans to know the functioning of your pituitary gland.
  • Kidney functioning tests may be advised by your doctor to monitor for any renal impairment.

Disease/Condition Glossary

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused due to two conditions: A) Central diabetes insipidus is a condition when your pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin that regulates fluid balance.

Hypophysectomy: It is the surgical removal of the hypophysis (pituitary gland) to treat cancerous or benign tumours.

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