Minirin Melt 120 mcg Tablet 10's
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Minirin Melt 120 mcg Tablet 10's is a hormone analogue that belongs to the class of ‘antihemophilic agents’ primarily used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination) polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).
Minirin Melt 120 mcg Tablet 10's contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, Minirin Melt 120 mcg Tablet 10's is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet 10's also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.
Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin Melt 120 mcg Tablet 10's include headache, nausea, abdominal cramp, flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.
Before starting Minirin Melt 120 mcg Tablet 10's, let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using Minirin Melt 120 mcg Tablet 10's, limit water and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using Minirin Melt 120 mcg Tablet 10's. Do not take or stop this medicine, if the doctor did not advise you to do so.
Minirin Melt 120 mcg Tablet 10's is a hormone analogue that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone, vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controls bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet 10's also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.
Before starting Minirin Melt 120 mcg Tablet 10's, let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin Melt 120 mcg Tablet 10's, limit water and other fluids' intake since it may lead to electrolyte imbalance. Inform your doctor if you have any allergic reactions or lactose intolerance before using Minirin Melt 120 mcg Tablet 10's. Please consult your doctor before starting Minirin Melt 120 mcg Tablet 10's if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination.
Drug-Drug Interaction: Minirin Melt 120 mcg Tablet 10's may interact with fits medicine (lamotrigine), antidepressants (escitalopram, fluoxetine, sertraline), and water pills (furosemide).
Drug-Food Interaction: Avoid alcohol since it may worsen the side effects and increase urination.
Drug-Disease Interaction: Tell your doctor before taking Minirin Melt 120 mcg Tablet 10's if you have a medical history of kidney disease, hyponatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention.
Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused due to two conditions: A) Central diabetes insipidus is a condition when your pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin that regulates fluid balance.
Hypophysectomy: It is the surgical removal of the hypophysis (pituitary gland) to treat cancerous or benign tumours.
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Alcohol
Unsafe
It is unsafe to consume alcohol since it may worsen the side effects and increase urination.
Pregnancy
Caution
Minirin Melt 120 mcg Tablet 10's is a pregnancy category B drug. It can cause pre-eclampsia in pregnant women leading to high blood pressure, oedema (swelling due to the build-up of fluid) and proteinuria (protein in the urine). Please consult your doctor before starting Minirin Melt 120 mcg Tablet 10's if you are pregnant or planning to conceive.
Breast Feeding
Caution
Minirin Melt 120 mcg Tablet 10's is excreted into the breast milk when used by a breastfeeding mother. Please seek medical advice before you start Minirin Melt 120 mcg Tablet 10's if you are nursing.
Driving
Caution
Do not drive or operate machinery if you experience any unmanageable side effects with Minirin Melt 120 mcg Tablet 10's.
Liver
Caution
Please let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Minirin Melt 120 mcg Tablet 10's.
Kidney
Caution
Minirin Melt 120 mcg Tablet 10's is contraindicated in patients with moderate to severe renal impairment. Please let your doctor know if you have any history of kidney diseases when prescribed Minirin Melt 120 mcg Tablet 10's.
Children
Safe if prescribed
Minirin Melt 120 mcg Tablet 10's can be prescribed to children by the doctor, depending on the disease. The doctor decides the right dose for a child based on his/her age and weight.