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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:15 PM IST

About Minirin Nasal Spray 2.5 ml

Minirin Nasal Spray 2.5 ml belongs to the class of 'antidiuretics', primarily used as replacement therapy in central cranial diabetes insipidus, a condition in which the body fails to control water balance, resulting in excessive urination. Minirin Nasal Spray 2.5 ml is also used to manage temporary polyuria (extreme urination) or polydipsia (extreme thirst) after head trauma or surgery in the pituitary gland.

Minirin Nasal Spray 2.5 ml contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone synthesized in the hypothalamus of the pituitary gland. When your body cannot produce enough vasopressin, Minirin Nasal Spray 2.5 ml is given to replace a low level of vasopressin. It mimics the natural hormone vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination. Thus, it prevents dehydration. 

Minirin Nasal Spray 2.5 ml is for intranasal use only. Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin Nasal Spray 2.5 ml include conjunctivitis/red eyes, weakness, headache, nasal congestion/stuffy nose, rhinitis/runny nose, nose bleeds, nausea, upset stomach, abdominal pain, and flushing (sense of warmth) of the face. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Before starting Minirin Nasal Spray 2.5 ml, let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), excessive fluid intake, high blood pressure, heart problems/failure, swelling or scarring of the nasal lining, and illnesses that cause fluid/mineral imbalance. While using Minirin Nasal Spray 2.5 ml, avoid drinking large amounts of fluid, including alcohol, since it could lead to the build-up of water in the body. Pregnant and breastfeeding women should consult their doctor before using Minirin Nasal Spray 2.5 ml. 

Uses of Minirin Nasal Spray 2.5 ml

Central cranial diabetes insipidus, polyuria, and polydipsia.

Medicinal Benefits

Minirin Nasal Spray 2.5 ml is a hormone analogue that contains Desmopressin, a synthetic form of Vasopressin (an antidiuretic hormone that controls fluid balance). Minirin Nasal Spray 2.5 ml mimics the natural hormone vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination. Minirin Nasal Spray 2.5 ml is not indicated for the treatment of nephrogenic diabetes insipidus.

Directions for Use

Intranasal solution/Nasal spray: Read the instruction leaflet (if provided) carefully before using and prime the nozzle, if required. Blow your nose. Tilt your head back and insert the tip of the nozzle into your nostril. Spray into the nostril while breathing in slightly. When pressing down the pump, apply even pressure and press down quickly to produce a consistent spray. Repeat the same process for another nostril if required. Wipe off the tip with a clean tissue and replace the cap.Nasal drops: Read the instruction leaflet (if provided) carefully and use it as suggested by the doctor. Insert the tip of the dropper into the end of the medicine dispensing tube marked with measurements. Squeeze the dropper until the solution has reached the desired measurement. You can also use a syringe to fill the tube. Hold the tip of the tube, gently insert it into one nostril, and put the other end of the tube into your mouth. Hold your breath, tilt back your head, and blow slowly through your mouth into the tube so the solution reaches your nose.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Minirin Nasal Spray 2.5 ml

  • Conjunctivitis/red eyes
  • Weakness
  • Headache
  • Nose bleeds
  • Nasal congestion/stuffy nose
  • Rhinitis/runny nose
  • Nausea
  • Upset stomach
  • Abdominal pain
  • Flushing of the face 

Drug Warnings

Before starting Minirin Nasal Spray 2.5 ml, let your doctor know if you have any history of allergic reactions to antidiuretic hormones, severe kidney disease, hyponatremia (low sodium levels in your body), excessive fluid intake, high blood pressure, heart failure, illnesses that cause fluid/mineral imbalance (cystic fibrosis), and fluid retention. Please consult your doctor before starting Minirin Nasal Spray 2.5 ml if you are pregnant, planning to conceive or are a breastfeeding mother. Alcohol consumption may interfere with the working of Minirin Nasal Spray 2.5 ml; hence it is advised to limit or avoid its intake. Minirin Nasal Spray 2.5 ml should be used in children only when prescribed by the doctor.

Drug Interactions

Drug-Drug Interaction: Minirin Nasal Spray 2.5 ml may interact with anti-diarrhoeal medicines (loperamide), antidiabetics (chlorpropamide, glibenclamide), high cholesterol-lowering drugs (clofibrate), pain killers (naproxen, ibuprofen), fits medicines (carbamazepine), antipsychotics (chlorpromazine), water pills (furosemide), and antidepressants (lithium, fluoxetine, sertraline).

Drug-Food Interaction: Avoid alcohol since it may interfere with the working of Minirin Nasal Spray 2.5 ml and increase urination. 

Drug-Disease Interaction: Tell your doctor before taking Minirin Nasal Spray 2.5 ml if you have a medical history of kidney diseases, hyponatremia, excess fluid intake, high blood pressure, heart failure, fluid/mineral imbalance, and fluid retention. 

Drug-Drug Interactions Checker List

  • LOPERAMIDE
  • CHLORPROPAMIDE
  • GLIBENCLAMIDE
  • CLOFIBRATE
  • NAPROXEN
  • IBUPROFEN
  • CARBAMAZEPINE
  • CHLORPROMAZINE
  • FUROSEMIDE
  • LITHIUM
  • FLUOXETINE
  • SERTRALINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Reduce the amount of salt and protein in your diet, which will help your kidneys to produce less urine.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
  • Optimal water intake is recommended to prevent dehydration due to excessive urination.

Special Advise

  • Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.
  • If you are more frequently urinating than usual, it is advised to consult your endocrinologist to check for any hormonal abnormalities.
  • Your doctor may advise kidney functioning tests to monitor for renal impairment.

Disease/Condition Glossary

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused due to following: 

A) Central diabetes insipidus: It is caused when the pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). It is characterized by excessive thirst (polydipsia) and excessive urination (polyuria).

B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin that regulates fluid balance.

About Minirin Nasal Spray 2.5 ml

Minirin Nasal Spray 2.5 ml belongs to the class of 'antidiuretics', primarily used as replacement therapy in central cranial diabetes insipidus, a condition in which the body fails to control water balance, resulting in excessive urination. Minirin Nasal Spray 2.5 ml is also used to manage temporary polyuria (extreme urination) or polydipsia (extreme thirst) after head trauma or surgery in the pituitary gland.

Minirin Nasal Spray 2.5 ml contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone synthesized in the hypothalamus of the pituitary gland. When your body cannot produce enough vasopressin, Minirin Nasal Spray 2.5 ml is given to replace a low level of vasopressin. It mimics the natural hormone vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination. Thus, it prevents dehydration. 

Minirin Nasal Spray 2.5 ml is for intranasal use only. Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin Nasal Spray 2.5 ml include conjunctivitis/red eyes, weakness, headache, nasal congestion/stuffy nose, rhinitis/runny nose, nose bleeds, nausea, upset stomach, abdominal pain, and flushing (sense of warmth) of the face. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Before starting Minirin Nasal Spray 2.5 ml, let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), excessive fluid intake, high blood pressure, heart problems/failure, swelling or scarring of the nasal lining, and illnesses that cause fluid/mineral imbalance. While using Minirin Nasal Spray 2.5 ml, avoid drinking large amounts of fluid, including alcohol, since it could lead to the build-up of water in the body. Pregnant and breastfeeding women should consult their doctor before using Minirin Nasal Spray 2.5 ml. 

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Consume Type

NASAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Minirin Nasal Spray 2.5 ml

Central cranial diabetes insipidus, polyuria, and polydipsia.

Medicinal Benefits

Minirin Nasal Spray 2.5 ml is a hormone analogue that contains Desmopressin, a synthetic form of Vasopressin (an antidiuretic hormone that controls fluid balance). Minirin Nasal Spray 2.5 ml mimics the natural hormone vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination. Minirin Nasal Spray 2.5 ml is not indicated for the treatment of nephrogenic diabetes insipidus.

Side Effects of Minirin Nasal Spray 2.5 ml

  • Conjunctivitis/red eyes
  • Weakness
  • Headache
  • Nose bleeds
  • Nasal congestion/stuffy nose
  • Rhinitis/runny nose
  • Nausea
  • Upset stomach
  • Abdominal pain
  • Flushing of the face 

Directions for Use

Intranasal solution/Nasal spray: Read the instruction leaflet (if provided) carefully before using and prime the nozzle, if required. Blow your nose. Tilt your head back and insert the tip of the nozzle into your nostril. Spray into the nostril while breathing in slightly. When pressing down the pump, apply even pressure and press down quickly to produce a consistent spray. Repeat the same process for another nostril if required. Wipe off the tip with a clean tissue and replace the cap.Nasal drops: Read the instruction leaflet (if provided) carefully and use it as suggested by the doctor. Insert the tip of the dropper into the end of the medicine dispensing tube marked with measurements. Squeeze the dropper until the solution has reached the desired measurement. You can also use a syringe to fill the tube. Hold the tip of the tube, gently insert it into one nostril, and put the other end of the tube into your mouth. Hold your breath, tilt back your head, and blow slowly through your mouth into the tube so the solution reaches your nose.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before starting Minirin Nasal Spray 2.5 ml, let your doctor know if you have any history of allergic reactions to antidiuretic hormones, severe kidney disease, hyponatremia (low sodium levels in your body), excessive fluid intake, high blood pressure, heart failure, illnesses that cause fluid/mineral imbalance (cystic fibrosis), and fluid retention. Please consult your doctor before starting Minirin Nasal Spray 2.5 ml if you are pregnant, planning to conceive or are a breastfeeding mother. Alcohol consumption may interfere with the working of Minirin Nasal Spray 2.5 ml; hence it is advised to limit or avoid its intake. Minirin Nasal Spray 2.5 ml should be used in children only when prescribed by the doctor.

Therapeutic Class

HORMONES

Drug-Drug Interactions Checker List

  • LOPERAMIDE
  • CHLORPROPAMIDE
  • GLIBENCLAMIDE
  • CLOFIBRATE
  • NAPROXEN
  • IBUPROFEN
  • CARBAMAZEPINE
  • CHLORPROMAZINE
  • FUROSEMIDE
  • LITHIUM
  • FLUOXETINE
  • SERTRALINE

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Reduce the amount of salt and protein in your diet, which will help your kidneys to produce less urine.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
  • Optimal water intake is recommended to prevent dehydration due to excessive urination.

Habit Forming

No

Special Advise

  • Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.
  • If you are more frequently urinating than usual, it is advised to consult your endocrinologist to check for any hormonal abnormalities.
  • Your doctor may advise kidney functioning tests to monitor for renal impairment.

Disease/Condition Glossary

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused due to following: 

A) Central diabetes insipidus: It is caused when the pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). It is characterized by excessive thirst (polydipsia) and excessive urination (polyuria).

B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin that regulates fluid balance.