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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma

About Mirago S 25 Combikit 1's

Mirago S 25 Combikit 1's is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control.
 
Mirago S 25 Combikit 1's contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Mirago S 25 Combikit 1's helps in treating overactive bladder.
 
You are advised to take Mirago S 25 Combikit 1's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Mirago S 25 Combikit 1's is not recommended for children as safety and efficacy have not been established. Mirago S 25 Combikit 1's may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption along with Mirago S 25 Combikit 1's as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Mirago S 25 Combikit 1's to rule out any side effects/interactions.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Mirago S 25 Combikit 1's

Overactive bladder syndrome

Medicinal Benefits

Mirago S 25 Combikit 1's is a combination of two drugs, namely: Solifenacin and Mirabegron. Mirago S 25 Combikit 1's is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, dysuria (painful or difficult urination). Solifenacin is an anti-cholinergic that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron is a beta-3 adrenergic agonist which relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Mirago S 25 Combikit 1's helps in treating an overactive bladder.

Side Effects of Mirago S 25 Combikit 1's

  • Constipation
  • Headache 
  • Dry mouth
  • Blurred vision
  • Vomiting
  • High blood pressure
  • Urinary tract infection

Directions for Use

Swallow Mirago S 25 Combikit 1's as a whole with water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Mirago S 25 Combikit 1's if you are allergic to any of its contents. Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Mirago S 25 Combikit 1's is not recommended for children. Mirago S 25 Combikit 1's may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption with Mirago S 25 Combikit 1's as it could lead to increased dizziness. 

Therapeutic Class

ANTICHOLINERGICS

Drug-Drug Interactions

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MirabegronEliglustat
Critical
SolifenacinMesoridazine
Critical

Drug-Drug Interactions

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MirabegronEliglustat
Critical
How does the drug interact with Mirago S 25 Combikit 1's:
Coadministration of Eliglustat and Mirago S 25 Combikit 1's can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mirago S 25 Combikit 1's with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
SolifenacinMesoridazine
Critical
How does the drug interact with Mirago S 25 Combikit 1's:
Using Mesoridazine together with Mirago S 25 Combikit 1's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Mirago S 25 Combikit 1's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
SolifenacinItraconazole
Critical
How does the drug interact with Mirago S 25 Combikit 1's:
The blood levels and effects of Mirago S 25 Combikit 1's may be greatly increased when combined with itraconazole.

How to manage the interaction:
Mirago S 25 Combikit 1's and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
SolifenacinPotassium chloride
Critical
How does the drug interact with Mirago S 25 Combikit 1's:
Taking Mirago S 25 Combikit 1's and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Mirago S 25 Combikit 1's with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
MirabegronBrexpiprazole
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
A combined use of Mirago S 25 Combikit 1's and Brexpiprazole may increase the level of Brexpiprazole in blood. This can increase the risk or severity of side effects.

How to manage the interaction:
There could be a possible interaction between Mirago S 25 Combikit 1's and Brexpipraole, it can be taken together if your doctor has advised them. However, if you experience drowsiness, fatigue, seizure, chest pain or tightness, irregular heart rates, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronAripiprazole
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
Combining Aripiprazole with Mirago S 25 Combikit 1's can increase the levels of Aripiprazole in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Mirago S 25 Combikit 1's and Aripiprazole together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
MirabegronThioridazine
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
Combine use of Mirago S 25 Combikit 1's and thioridazine may raise the blood levels of thioridazine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mirago S 25 Combikit 1's and thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience stomach pain, diarrhea, dehydration, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronPimozide
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
Combined use of Mirago S 25 Combikit 1's and Pimozide may increase the level of pimozide in the blood. This can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Mirago S 25 Combikit 1's and Pimozide may lead to an interaction but they can be taken together if your doctor has prescribed them. However, if you experience drowsiness, blurred vision, dry mouth, constipation, low blood pressure, tremors, trembling of hands, arms, legs, jaw and face, balance and Speech difficulty, or abnormal muscle movements consult a doctor. Do not discontinue any medications without consulting a doctor.
MirabegronVenetoclax
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
Coadministration of Mirago S 25 Combikit 1's and Venetoclax may significantly increase the blood levels and effects of Venetoclax. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possible interaction between Mirago S 25 Combikit 1's and Venetoclax, but they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, diarrhea, fatigue, fever, chills, bleeding problems, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronTamoxifen
Severe
How does the drug interact with Mirago S 25 Combikit 1's:
Coadministration of Mirago S 25 Combikit 1's and Tamoxifen may reduce the effects of tamoxifen.

How to manage the interaction:
Taking Mirago S 25 Combikit 1's and Tamoxifen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience painful urination, constipation, dry mouth, headache, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ACETAMINOPHEN
  • ALBUTEROL

Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Quit smoking.
  • Take 6-8glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Overactive bladder (OAB): Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control. The contraction or tightening of bladder muscles causes bladder spasms. Continuous contractions may cause an urge to urinate. Overactive bladder is characterised by involuntary leakage of urine, excessive urination, and urgent need to urinate. The common causes of bladder spasms are urinary tract infections, drinking too much caffeine or alcohol, diabetes, constipation, impaired kidney function, bladder stones, enlarged prostate, or neurological disorders. Symptoms of overactive bladder include urinating more than 8 times a day and more than 2 times at night, strong and sudden need to urinate, leakage of urine, and loss of bladder control.

Mirago S 25 Combikit 1's Substitute

Substitutes safety advice
  • Mirago S 25 Tablet 10's

    40.50per tablet
  • Mirbeg S 25 Tablet 10's

    40.77per tablet
  • Mirabig-S 25 Tablet 10's

    39.96per tablet
  • Bladmir-S 25 Tablet 10's

    40.46per tablet
  • Megatas-S 25 Tablet 10's

    42.48per tablet
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