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Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Composition :

REPAGLINIDE-2MG

Manufacturer/Marketer :

MEDICAMEN BIOTECH LTD

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mlrepa 2 Tablet

Mlrepa 2 Tablet belongs to the category of medicines called 'anti-diabetic primarily used for the management and treatment of type 2 diabetes, especially in persons whose sugar levels are too high and cannot be only controlled by dieting and exercising. Type 2 diabetes is a condition that occurs when there is either less insulin or available insulin is not properly utilized by our body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of total diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Mlrepa 2 Tablet contains 'Repaglinide' is a meglitinide that works by increasing the amount of insulin released by the pancreas. It starts acting so quickly on controlling blood sugar levels immediately after a meal. Mlrepa 2 Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Your doctor will decide what dose should be taken for better advice, and it can change timely depending upon your condition. In some cases, you may experience headache, stomach pain, a sign of a common cold, diarrhoea, joint pain and back pain. Most of these side effects of Mlrepa 2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You should not take Mlrepa 2 Tablet if you have type 1 diabetes mellitus, renal impairment, metabolic acidosis, including diabetic ketoacidosis (excess acids in your blood), severe kidney, or liver disease. Please inform your doctor if you have any heart disease, are planning to get pregnant, or are breastfeeding. Mlrepa 2 Tablet should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Mlrepa 2 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).

Uses of Mlrepa 2 Tablet

Type 2 Diabetes Mellitus.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mlrepa 2 Tablet belongs to the group of medicines called “anti-diabetic” indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and is even not controlled by diet and exercise alone. Mlrepa 2 Tablet consists of Repaglinide belongs to a class of meglitinide that works by increasing the amount of insulin released by the pancreas. It starts acting so quickly on controlling blood sugar levels immediately after a meal. Mlrepa 2 Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mlrepa 2 Tablet

  • Headache
  • Stomach pain
  • Sign of a common cold
  • Diarrhoea
  • Joint pain
  • Back pain

Drug Warnings

Mlrepa 2 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (in this condition, there is too much lactic acid accumulated in the blood). Inform your doctor if you take other antidiabetic drugs to adjust the dosage of Mlrepa 2 Tablet accordingly. Do not abruptly stop taking Mlrepa 2 Tablet midway if the doctor did not advise you. Mlrepa 2 Tablet may cause hypoglycaemia (low blood sugar), hence it is advised to make healthy food with enough calories and avoid heavy exercises.  Mlrepa 2 Tablet is not recommended for use during pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Mlrepa 2 Tablet is not recommended for people younger than 18 years or over 75 years of age.  Before you start taking Mlrepa 2 Tablet , tell your doctor if you have serious heart disease or if you have had a stroke, low blood pressure (hypotension), and severe liver or kidney disease. Avoid alcohol intake while using Mlrepa 2 Tablet since it may increase the risk of lactic acidosis. 

Drug-Drug Interactions

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RepaglinideGatifloxacin
Critical
RepaglinideGemfibrozil
Critical

Drug-Drug Interactions

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RepaglinideGatifloxacin
Critical
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Mlrepa 2 Tablet can be taken with Gatifloxacin if prescribed by the doctor. However, consult the doctor if you experience unusual symptoms. Do not stop using any medications without first talking to your doctor.
RepaglinideGemfibrozil
Critical
How does the drug interact with Mlrepa 2 Tablet:
When Mlrepa 2 Tablet is taken with Gemfibrozil, the level of Mlrepa 2 Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mlrepa 2 Tablet with Gemfibrozil can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RepaglinideLevofloxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with levofloxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although concomitant administration of levofloxacin with Mlrepa 2 Tablet can result in an interaction, they can be taken if a doctor has advised it. Inform doctor if you experience hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose), or if you have a lack of blood glucose control. Headache, dizziness, sleepiness, anxiety, confusion, a shaking sensation, nausea, hunger, weakness, sweat, palpitation, and fast pulse are all symptoms of hypoglycemia. Hyperglycemia symptoms may include increased thirst, increased appetite, and increased urine. Do not stop using any medications without talking to a doctor.
RepaglinideEnoxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with enoxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Enoxacin can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms of hypoglycemia(low blood sugar), such as headache, dizziness, drowsiness, anxiety, weakness, tremors, nausea, hunger, sweating, and palpitation and symptoms of hyperglycemia(high blood sugar) such as increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
RepaglinideCiprofloxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Taking Mlrepa 2 Tablet with ciprofloxacin can effect blood sugar levels, both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and Mlrepa 2 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, tell your doctor if you experience hypoglycemia, hyperglycemia, or a decline in blood glucose control. Hypoglycemia can cause headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, sweat, palpitations, and a rapid heartbeat. Increased hunger, thirst, and urine are all possible signs of hyperglycemia. Consult your doctor if you experience any of the above symptoms.
RepaglinideGemifloxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with gemifloxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Gemifloxacin can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms of hypoglycemia or hyperglycemia, such as headache, dizziness, drowsiness, anxiety, weakness, tremors, nausea, hunger, sweating, and palpitation, increased thrust, increased hunger, and increased urination. Do not discontinue any medicine without consulting a doctor.
RepaglinideNalidixic acid
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with nalidixic acid can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Nalidixic acid can possibly result in an interaction, they can be taken together if prescribed by your doctor. Consult the doctor if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without talking to a doctor.
RepaglinideCinoxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Taking Mlrepa 2 Tablet with cinoxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Cinoxacin can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms of hypoglycemia, such as headache, dizziness, drowsiness, anxiety, weakness, tremors, nausea, hunger, sweating, and fast heartbeat. Do not discontinue any medicine without consulting a doctor.
RepaglinideMoxifloxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with moxifloxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Moxifloxacin can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms of hypoglycemia, such as headache, dizziness, drowsiness, anxiety, weakness, tremors, nausea, hunger, sweating, palpitation, or hyperglycemia such as increased urination, increased thrust, or increased hunger. Do not discontinue any medicine without consulting a doctor.
RepaglinideGrepafloxacin
Severe
How does the drug interact with Mlrepa 2 Tablet:
Coadministration of Mlrepa 2 Tablet with grepafloxacin can affect blood glucose levels. Both high blood glucose (hyperglycemia) and, to a lesser extent, low blood glucose (hypoglycemia).

How to manage the interaction:
Although taking Mlrepa 2 Tablet together with Grepafloxacin can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms of hypoglycemia or hyperglycemia, such as headache, dizziness, drowsiness, anxiety, weakness, tremors, nausea, hunger, sweating, and palpitation, increased thrust, increased hunger, and increased urination. Do not discontinue any medicine without consulting a doctor.

Drug-Food Interactions

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REPAGLINIDE-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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REPAGLINIDE-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Mlrepa 2 Tablet and grapefruit or grapefruit juice together can increase the blood levels and effects of Mlrepa 2 Tablet. Avoid the consumption of Grapefruit or grapefruit juice.

Diet & Lifestyle Advise

  •  
  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Mlrepa 2 Tablet contains Repaglinide that works by increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.

Hypoglycemia refers to low blood sugar levels, and it is one of the side effects of Mlrepa 2 Tablet . Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

If a person is getting unusually thrust or passing urine frequently more than normal while taking Mlrepa 2 Tablet , they should tell it to their doctor as it may be a sign that there is too much sugar in their blood and treatment needs to be adjusted. It may also because of dehydration as Mlrepa 2 Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty, please consult your doctor.

Your doctor may suggest you go for a regular test for sugar (glucose) in your blood or urine to monitor if diabetes has controlled or not.

Diabetes is a chronic medical condition that means lifelong, so its treatment should also continue for the whole life, so keep taking Mlrepa 2 Tablet unless your doctor advises you to stop the medicine.

Mlrepa 2 Tablet should be used with caution in heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, foot ulcers, nerve damage, low blood pressure and severe infections. Mlrepa 2 Tablet is contraindicated in patients with renal impairment and diabetic ketoacidosis.

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

Drug-Drug Interactions Checker List

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Special Advise

  •  
  • It is advised to monitor your blood sugar levels regularly.
  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice.
  • Take short, frequent meals, avoid prolonged fasting when taking this drug. Beware of hypoglycaemia symptoms include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, impacting the functioning of various organs in the body).
  • Try to quit smoking and reduce carbohydrate-rich food like potato, rice, mangoes, bread, sugar etc.
  • Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

Disease/Condition Glossary

Diabetes mellitus 2, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots.

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