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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Mofilet-250 Tablet

Mofilet-250 Tablet belongs to a class of medications called ‘immunosuppressants’ used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

Mofilet-250 Tablet contains ‘Mycophenolate mofetil’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (a type of white blood cell that attacks foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Take Mofilet-250 Tablet as prescribed. Your doctor will advise you on how often you take Mofilet-250 Tablet based on your medical condition. The common side effects of Mofilet-250 Tablet are diarrhoea, vomiting, decreased white blood cells and red blood cell count and infections. Consult your doctor right away if any of these side effects persist or worsen.

Do not take Mofilet-250 Tablet if you are allergic to ‘mycophenolate mofetil’ or any ingredients present in it. Also, do not take it if you are pregnant, planning to become pregnant, or not using effective contraception and breastfeeding. It can cause birth defects/congenital disabilities in the unborn baby, so make sure you take a pregnancy test before using Mofilet-250 Tablet if you are a woman of childbearing potential. You are advised to use effective contraception while taking Mofilet-250 Tablet . It can increase the risk of skin cancer, so wear protective clothing and limit exposure to sunlight. It increases the risk of infections as it can suppress the immune system. Do not donate blood or sperm without informing your doctor. Please do not take any vaccinations as it may be less effective.

Uses of Mofilet-250 Tablet

Prevent organ transplant rejection

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Suspension: It is available as a dry powder and mixed with the liquid (mostly boiled and cooled water) up to the mark. Shake the bottle well before each use and take the dose as prescribed.

Medicinal Benefits

Mofilet-250 Tablet contains ‘Mycophenolate mofetil’ which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reactions) in the body. It is preferred to use over steroids, which have long-term side effects.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mofilet-250 Tablet
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you observe any new and unusual marks on your skin, discontine the drug and reach out to your doctor for advice.
  • If the cancer is in the early stage, your doctor may surgically remove the tumour.
  • Radiation, cancer medications, or targeted treatments may be recommended based on the severity of the cancer.
  • Consult a dietitian to make sure you are eating the right food and getting enough nutrition during cancer treatment.
  • Eat your meals in small amounts with a gap of 2-3 hours.
  • Do light physical activities to relieve tiredness and improve your overall well-being.

Drug Warnings

Before taking Mofilet-250 Tablet , inform your doctor if you have a sign of infection such as a fever or sore throat, have any unexpected bruising or bleeding, have a history of digestive system problems such as a stomach ulcer, are planning to become pregnant, get pregnant while taking Mofilet-250 Tablet , and have rare hereditary disorders such as Lesch-Nyhan or Kelley-Seegmiller syndrome (conditions caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl-transferase (HGPRT)). Limit your exposure to sunlight as Mofilet-250 Tablet increases the risk of skin cancer. Do not donate blood while taking Mofilet-250 Tablet and for at least 60 days after discontinuing the therapy. Men should not donate sperm while taking Mofilet-250 Tablet for at least 90 days after discontinuing the therapy. Please do not take any vaccinations (live vaccine) as it will not be much effective. The oral suspension contains aspartame (sweetener and a phenylalanine source), so it should be used with caution in patients with phenylketonuria (a birth defect/congenital disability that causes decreased metabolism of phenylalanine).

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Mofilet-250 Tablet:
Coadministration of Colestipol with Mofilet-250 Tablet can reduce its absorption and action in the body. This can lead to low treatment results.

How to manage the interaction:
Taking Mofilet-250 Tablet with Colestipol is not recommended as it can result in an interaction, it can be taken if your doctor has advised it.
How does the drug interact with Mofilet-250 Tablet:
Combined use of Mofilet-250 Tablet and Infliximab can increase the risk or severity of developing serious infections.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Infliximab, but they can be taken together if your doctor has prescribed them. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mofilet-250 Tablet:
Coadministration of Mofilet-250 Tablet and Colesevelam can decrease the levels and effects of Mofilet-250 Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Colesevelam, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation, pain in the stomach area, low blood cell counts, infections, sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mofilet-250 Tablet:
Taking Mofilet-250 Tablet and Golimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Golimumab, but they can be taken together if your doctor has prescribed them. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mofilet-250 Tablet:
Taking Mofilet-250 Tablet and Adalimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Mofilet-250 Tablet and Adalimumab together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Mofilet-250 Tablet:
Combine use of Nafcillin and Mofilet-250 Tablet may reduce the blood levels and effects of Mofilet-250 Tablet.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Nafcillin, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhoea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mofilet-250 Tablet:
Coadministration of Mofilet-250 Tablet and Desogestrel can decrease the levels and action of Desogestrel.

How to manage the interaction:
Co-administration of Desogestrel with Mofilet-250 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms: abnormal menstruation, dryness of the vagina, or increased hot flushes or if you're looking for other birth control options, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mofilet-250 Tablet:
Co-administration of Mofilet-250 Tablet and Cholestyramine may decrease the effectiveness of Mofilet-250 Tablet.

How to manage the interaction:
Although there is an interaction between Mofilet-250 Tablet and Cholestyramine, it can be taken together if your doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mofilet-250 Tablet:
Co-administration of Dienogest with Mofilet-250 Tablet may decrease the levels and action of Dienogest.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Dienogest, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mofilet-250 Tablet:
Co-administration of Ferrous sulfate with Mofilet-250 Tablet decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mofilet-250 Tablet and Ferrous sulfate, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 
  • Avoid eating raw or undercooked food. 
  • Protect yourself from exposure to sunlight and soil. Wear a long-sleeve shirt, hat, long pants and shoes while going outdoors. Also, wear sunscreen with high SPF. 
  • Stay away from people who are sick. 
  • Limit alcohol consumption and quit smoking. 
  • Talk with your doctor at least 2 months before leaving, if you plan to travel, especially to developing countries. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mofilet-250 Tablet belongs to the group of medications called ‘immunosuppressants’. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.

Mofilet-250 Tablet can suppress the immune system and can increase the risk of skin cancer. So, you should avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).

Mofilet-250 Tablet can suppress the immune system. So, you should not donate blood while using Mofilet-250 Tablet and at least 60 days after stopping treatment as it makes you more prone to infections. Besides, men should not donate sperm while using Mofilet-250 Tablet for at least 90 days after stopping the treatment.

It is not advised to get pregnant while using Mofilet-250 Tablet as it may cause birth defects/congenital disabilities in the unborn baby. So, it would help if you took an effective and reliable contraceptive while using Mofilet-250 Tablet , even when men are taking Mofilet-250 Tablet .

Mofilet-250 Tablet is given to stop rejection of the transplanted organ. If you abruptly stop taking this drug, it might result in rejecting the transplanted organ. So, check with your doctor if you want to stop using Mofilet-250 Tablet .

Drug-Drug Interactions Checker List

  • AZATHIOPRINE
  • ACICLOVIR
  • GANCICLOVIR
  • RIFAMPICIN
  • NORFLOXACIN+METRONIDAZOLE

Special Advise

  • Your doctor may advise you to take regular blood tests to monitor blood cell counts and liver function. In general, the tests are done every 2 to 4 weeks in the initial two months, followed by once every 2 to 3 months.
  • Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element and tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs are given to such patients to suppress your immune system, stopping it from attacking the newly transplanted organs. Warnings signs of rejection are flu-like symptoms such as chills, headache, nausea, or vomiting, fever higher than 100o F, newly found pain at the region of the transplanted organ, weight gain and fatigue.

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