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Prescription drugWhats That
Composition :
CANAGLIFLOZIN-300MG
Manufacturer/Marketer :
Johnson & Johnson Pvt Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Critical
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Motivyst 300 Tablet:
Co-administration of Motivyst 300 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Motivyst 300 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
Co-administration of Motivyst 300 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Motivyst 300 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Motivyst 300 Tablet:
Co-administration of Morphine with Motivyst 300 Tablet may increase the blood levels and side effects of morphine.
How to manage the interaction:
Co-administration of Morphine with Motivyst 300 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Co-administration of Morphine with Motivyst 300 Tablet may increase the blood levels and side effects of morphine.
How to manage the interaction:
Co-administration of Morphine with Motivyst 300 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Drug-Food Interactions
CANAGLIFLOZIN-300MGHerbal products/medicines
Moderate
Drug-Food Interactions
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CANAGLIFLOZIN-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort
How to manage the interaction:
Concomitant use of Motivyst 300 Tablet with St. John's Wort may decrease the serum concentration of Motivyst 300 Tablet. Consult the prescriber, the doctor may adjust the dose of Motivyst 300 Tablet if you are taking St.John's wort.
St. John’S Wort
How to manage the interaction:
Concomitant use of Motivyst 300 Tablet with St. John's Wort may decrease the serum concentration of Motivyst 300 Tablet. Consult the prescriber, the doctor may adjust the dose of Motivyst 300 Tablet if you are taking St.John's wort.
Author Details
Drug-Diseases Interactions
CANAGLIFLOZIN-300MGOther diseases of liver
Severe
CANAGLIFLOZIN-300MGOther disorders of kidney and ureter, not elsewhere classified
Severe
Drug-Diseases Interactions
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CANAGLIFLOZIN-300MGOther diseases of liver
Severe
How does the disease interact with Motivyst 300 Tablet:
Due to a lack of clinical data, the SGLT2 inhibitors ertugliflozin and Motivyst 300 Tablet are not advised for use in patients with severe hepatic impairment. It is advised to exercise caution when using dapagliflozin in patients with severe hepatic impairment. Patients with mild or moderate hepatic impairment do not require dosage modifications.
How to manage the interaction:
Motivyst 300 Tablet is not recommended for use in patients with severe hepatic impairment due to a lack of clinical data.
Due to a lack of clinical data, the SGLT2 inhibitors ertugliflozin and Motivyst 300 Tablet are not advised for use in patients with severe hepatic impairment. It is advised to exercise caution when using dapagliflozin in patients with severe hepatic impairment. Patients with mild or moderate hepatic impairment do not require dosage modifications.
How to manage the interaction:
Motivyst 300 Tablet is not recommended for use in patients with severe hepatic impairment due to a lack of clinical data.
CANAGLIFLOZIN-300MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Motivyst 300 Tablet:
In patients with deteriorating renal function, the glucose-lowering benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are reduced. In addition, those who have impaired renal function (eGFR less than 60 mL/min/1.73 m2), those who are elderly, and those on loop diuretics may be more susceptible to deleterious effects of volume depletion like hypotension and acute kidney injury.
How to manage the interaction:
The glucose-lowering effects of the medicine may be decreased in patients with worsening kidney function. Renal function should be evaluated prior to treatment initiation and monitored regularly in at-risk patients.
In patients with deteriorating renal function, the glucose-lowering benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are reduced. In addition, those who have impaired renal function (eGFR less than 60 mL/min/1.73 m2), those who are elderly, and those on loop diuretics may be more susceptible to deleterious effects of volume depletion like hypotension and acute kidney injury.
How to manage the interaction:
The glucose-lowering effects of the medicine may be decreased in patients with worsening kidney function. Renal function should be evaluated prior to treatment initiation and monitored regularly in at-risk patients.
CANAGLIFLOZIN-300MGHypotension
Moderate
How does the disease interact with Motivyst 300 Tablet:
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors cause intravascular volume contraction which may lead to symptomatic hypotension after treatment initiation especially in the elderly, in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics . Volume status should be assessed and corrected before starting treatment and patients should be monitored during therapy.
How to manage the interaction:
Low blood pressure might occur in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics. Patients should be monitored during therapy.
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors cause intravascular volume contraction which may lead to symptomatic hypotension after treatment initiation especially in the elderly, in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics . Volume status should be assessed and corrected before starting treatment and patients should be monitored during therapy.
How to manage the interaction:
Low blood pressure might occur in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics. Patients should be monitored during therapy.
CANAGLIFLOZIN-300MGBacterial infection of unspecified site
Moderate
How does the disease interact with Motivyst 300 Tablet:
The usage of sodium-glucose cotransporter 2 (SGLT-2) inhibitors has been linked to an increased risk of genital mycotic infections. When administering this medication to patients who have a history of genital mycotic infections or who have not undergone circumcision, caution should be taken because they are more susceptible to experience genital mycotic infections. Observe and treat as necessary.
How to manage the interaction:
Genital mycotic infections may occur. Care should be exercised in patients who have a history of genital mycotic infections or who are uncircumcised as these patients are more likely to develop genital mycotic infections. Monitoring the patient for infections is advised.
The usage of sodium-glucose cotransporter 2 (SGLT-2) inhibitors has been linked to an increased risk of genital mycotic infections. When administering this medication to patients who have a history of genital mycotic infections or who have not undergone circumcision, caution should be taken because they are more susceptible to experience genital mycotic infections. Observe and treat as necessary.
How to manage the interaction:
Genital mycotic infections may occur. Care should be exercised in patients who have a history of genital mycotic infections or who are uncircumcised as these patients are more likely to develop genital mycotic infections. Monitoring the patient for infections is advised.
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