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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

Manufacturer/Marketer :

Consume Type :

Oral

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About Mtz-15 Tablet

Mtz-15 Tablet belongs to a group of medicines called anti-depressants used to treat the major depressive disorder. Additionally, Mtz-15 Tablet is sometimes used to treat obsessive-compulsive disorder (OCD), and anxiety disorders. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Mtz-15 Tablet contains ‘Mirtazapine’, which increases the activity of mood-enhancing chemical messengers such as serotonin and norepinephrine in the brain, which communicate between brain cells, thereby regulating mood and treats depression.

You are advised to take Mtz-15 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as sleepiness, drowsiness, weight gain, dry mouth, headache, nausea, vomiting, and tiredness. Talk to your doctor if you experience these side-effects persistently.

Please do not stop taking Mtz-15 Tablet without consulting your doctor, as it could lead to recurring symptoms. Consult your doctor if you are pregnant or breastfeeding. Mtz-15 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Mtz-15 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Mtz-15 Tablet

Depression

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Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible tablet/Tablet DT: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Key Benefits

Mtz-15 Tablet belongs to a group of medicines called tetracyclic anti-depressants. Mtz-15 Tablet is used to treat major depressive disorder. Additionally, Mtz-15 Tablet is sometimes used to treat obsessive-compulsive disorder (OCD) and anxiety disorders. Mtz-15 Tablet  works by increasing mood-enhancing chemical messengers such as serotonin and norepinephrine in the brain, which communicate between brain cells, thereby regulating mood and treating depression.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mtz-15 Tablet
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Do not take Mtz-15 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) such as moclobemide, tranylcypromine, selegiline or have taken them in the last 14 days. Inform your doctor if you have/had epilepsy, low blood pressure, urination problems or enlarged prostate, glaucoma, diabetes, schizophrenia, mania, dementia (memory loss), heart, kidney or liver problems. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Mtz-15 Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol along with Mtz-15 Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Mtz-15 Tablet may cause dizziness on standing suddenly.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mtz-15 Tablet:
Using Mtz-15 Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Mtz-15 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mtz-15 Tablet:
Using Zolmitriptan together with Mtz-15 Tablet can increase the risk of a rare but serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although there is a possible interaction between Mtz-15 Tablet and Zolmitriptan, you can take these medicines together if prescribed by your doctor. If you notice any of these signs - like confusion, shaking, or stomach discomfort - it's a good idea to reach out to a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mtz-15 Tablet:
Using pimozide together with Mtz-15 Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pimozide with Mtz-15 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mtz-15 Tablet:
Using Rasagiline together with Mtz-15 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Mtz-15 Tablet with rasagiline is not recommended, but can be taken together if prescribed by your doctor. However, if you experience confusion, hallucination(seeing or hearing things that does not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Mtz-15 Tablet:
Using cisapride together with Mtz-15 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Mtz-15 Tablet with Cisapride is generally not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MirtazapineMesoridazine
Critical
How does the drug interact with Mtz-15 Tablet:
Using mesoridazine together with Mtz-15 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mtz-15 Tablet with Mesoridazine is not recommended, please consult your doctor before taking it.
How does the drug interact with Mtz-15 Tablet:
Using Linezolid together with Mtz-15 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Linezolid with Mtz-15 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mtz-15 Tablet:
When Vilazodone is taken with Mtz-15 Tablet, might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Mtz-15 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea call a doctor right away. Do not stop using any medications without a doctor's advice.
MirtazapineEsketamine
Severe
How does the drug interact with Mtz-15 Tablet:
Combining Esketamine with Mtz-15 Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Although taking Mtz-15 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to call a doctor know right away. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Mtz-15 Tablet:
Taking Mtz-15 Tablet with Rizatriptan can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Mtz-15 Tablet and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

[PSYCHOTHERAPEUTICS]
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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Mtz-15 Tablet as it may cause an increased sedative effect.

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Pregnancy

Consult your doctor

Mtz-15 Tablet belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Mtz-15 Tablet may pass into breastmilk. Consult your doctor before taking Mtz-15 Tablet , your doctor will decide whether Mtz-15 Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Mtz-15 Tablet may cause sleepiness, dizziness and drowsiness. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Mtz-15 Tablet is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Mtz-15 Tablet works by increasing mood-enhancing chemical messengers such as serotonin and norepinephrine in the brain, which communicate between brain cells, thereby regulating mood and treating depression.

Mtz-15 Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Do not discontinue Mtz-15 Tablet without consulting your doctor, as it could lead to recurring symptoms. To treat your condition effectually, continue taking Mtz-15 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mtz-15 Tablet .

Dry mouth could be a side-effect of Mtz-15 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Orthostatic hypotension could be a side-effect of Mtz-15 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Please consult your doctor before taking Mtz-15 Tablet if you have glaucoma as it might cause increased pressure in the eye.

Consult your doctor before taking Mtz-15 Tablet if you have diabetes, as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Mtz-15 Tablet . Talk to your doctor if you experience fluctuations in blood sugar levels.

Constipation could be a side-effect of Mtz-15 Tablet . Drink plenty of fluids and eat high-fibre foods such as vegetables, fruits, and cereals. Talk to your doctor if the condition persists or worsens.

Country of origin

INDIA

Manufacturer/Marketer address

308-310 Dwarkesh Complex, Sun Pharma Road, Po:Atladra, Vadodara-390 012., Gujarat, India.
Other Info - MTZ0001

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