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Reviewed By Hari Kumar , MBBS
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Composition :

GEMCITABINE-1000MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Mygem 1Gm Inj

Mygem 1Gm Inj belongs to the group of anti-cancer drugs called cytotoxics used alone or in combination with other anti-cancer drugs to treat various types of cancers like breast cancer, pancreatic cancer, non-small cell lung cancer, bladder cancer, and ovarian cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body.

Mygem 1Gm Inj contains Gemcitabine which works by interfering with the synthesis of DNA, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Mygem 1Gm Inj is very effective in controlling cancer cells from multiplying and is used in the treatment of various types of cancers. 

A healthcare professional will administer Mygem 1Gm Inj. Do not self-administer. Mygem 1Gm Inj may cause certain common side effects such as nausea, hair loss, skin rash, vomiting, and oedema. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Talk to your doctor if you are planning to father a child before taking Mygem 1Gm Inj; your doctor may advise you regarding sperm storage. Avoid taking alcohol with Mygem 1Gm Inj.

Uses of Mygem 1Gm Inj

Breast Cancer, Pancreatic Cancer, Non-small-cell Lung Cancer, Bladder Cancer, and Ovarian Cancer.

Directions for Use

A healthcare professional will administer Mygem 1Gm Inj. Do not self-administer.

Medicinal Benefits

Mygem 1Gm Inj is an anti-cancer drug used in the treatment of various types of cancers. Mygem 1Gm Inj is used either independently or in conjunction with other chemotherapy medications to treat breast cancer, pancreatic cancer, non-small cell lung cancer, bladder cancer, and ovarian cancer. Mygem 1Gm Inj works by interfering with DNA synthesis. It blocks the production of new DNA, by locking itself into the DNA strands and inhibiting any further proliferation or growth of the cell. Hence, Mygem 1Gm Inj has widespread application in the field of oncology (cancer-related medicine) and chemotherapy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mygem 1Gm Inj
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Tell your doctor if you notice any unusual symptoms after taking the medication, such as flat purple, or red spots on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Drink plenty of fluids to stay hydrated, and eat fruits and vegetables or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.
  • Regularly wash your hands with alcohol-based sanitizer or soap and water.
  • Also, avoid sharing personal items like glasses or utensils with other individuals.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Drug Warnings

Mygem 1Gm Inj should not be used in case of any known allergy to any of the components. Mygem 1Gm Inj should be used with caution in case of high risk or previous history of heart disease, vascular disease, liver problems, kidney disease or alcoholism. Keep your doctor informed if you suffer from any shortness of breath, kidney problems, hypertension diabetes or epilepsy. Avoid Mygem 1Gm Inj during pregnancy and breastfeeding. Offer a detailed medical history, vaccination history, and inform the doctor especially if you are on any radiotherapy.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mygem 1Gm Inj:
Taking thalidomide together with Mygem 1Gm Inj may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Mygem 1Gm Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mygem 1Gm Inj:
Coadministration of Ketoconazole and Mygem 1Gm Inj may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Mygem 1Gm Inj together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience a fever, chills, joint pain or swelling, unusual bleeding or bruises, skin rash, itching, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Mygem 1Gm Inj:
Mygem 1Gm Inj can cause higher levels of Deferiprone in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Mygem 1Gm Inj and Deferiprone, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mygem 1Gm Inj:
Combining Mygem 1Gm Inj with Teriflunomide can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Mygem 1Gm Inj and Teriflunomide, but it can be taken if prescribed by a doctor. If you notice any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain or burning when urinating, joint pain, swelling, bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, dark urine or bleeding contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GemcitabineVoclosporin
Severe
How does the drug interact with Mygem 1Gm Inj:
When Mygem 1Gm Inj is taken with Voclosporin, the amount of Mygem 1Gm Inj in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Mygem 1Gm Inj and Voclosporin, but it can be taken if prescribed by a doctor. If you have any of these symptoms fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mygem 1Gm Inj:
Combining Adalimumab with Mygem 1Gm Inj can increase the risk of side effects like developing serious infections.

How to manage the interaction:
Although taking Mygem 1Gm Inj and Adalimumab together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like feeling sick, having a fever, diarrhea, a sore throat, muscle aches, weight loss, pain when you pee, or having trouble breathing it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
GemcitabineGolimumab
Severe
How does the drug interact with Mygem 1Gm Inj:
Combining Mygem 1Gm Inj with Golimumab can increase the risk of infections.

How to manage the interaction:
Taking Mygem 1Gm Inj with Golimumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain/burning when you urinate. Do not stop using any medications without a doctor's advice.
GemcitabineCertolizumab
Severe
How does the drug interact with Mygem 1Gm Inj:
Combining Mygem 1Gm Inj with Certolizumab can increase the risk of infections.

How to manage the interaction:
Co-administration of Mygem 1Gm Inj with Certolizumab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mygem 1Gm Inj:
Combining Mygem 1Gm Inj with Leflunomide can increase the risk or severity of developing serious infection

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Mygem 1Gm Inj, but it can be taken if prescribed by a doctor. If you notice any of these signs - like feeling sick, having a fever or chills, diarrhea, a sore throat, muscle pain, trouble breathing, weight loss, pain or burning urination, joint pain, swelling or bruising, a rash or itching, loss of appetite, feeling tired, or having nausea, vomiting, dark urine, or bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mygem 1Gm Inj:
Coadministration of Tofacitinib and Mygem 1Gm Inj can lead to or increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Tofacitinib and Mygem 1Gm Inj, but it can be taken if advised by a doctor. Contact your doctor immediately if you develop symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
  • Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Avoid taking Mygem 1Gm Inj with alcohol as there may be an interaction.
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid tobacco use.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Mygem 1Gm Inj Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mygem 1Gm Inj works blocking DNA synthesis and causing cell death, thereby preventing the cells from proliferating beyond normal.

Men taking Mygem 1Gm Inj are advised not to father a child during the treatment with Mygem 1Gm Inj and for 6months after the treatment. Consult your doctor before starting Mygem 1Gm Inj if you are planning to father a child. Your doctor may advise you regarding sperm storage.

If you suffer from CKD, please consult with your doctor before using Mygem 1Gm Inj and discuss any concerns with them. Mygem 1Gm Inj is to be used with caution in those suffering from kidney and liver problems.

Mygem 1Gm Inj might cause low white blood cell count leading to increased risk of infections. Consult your doctor if you have a fever, sweating, and any signs of infections.

Mygem 1Gm Inj may cause bleeding and bruising due to less platelet count. Consult a doctor if you notice unexpected bruising, pinkish or reddish urine, bleeding from gums, mouth, or nose.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • ACECLOFENAC
  • ACETAZOLAMIDE
  • ABACAVIR
  • ABATACEPT
  • ACENOCOUMAROL

Special Advise

  • Discuss contraception with your doctor while taking Mygem 1Gm Inj.
  • Men are advised not to father a child during and up to 6 months of treatment with Mygem 1Gm Inj. In case of any concerns, please discuss them with your treating doctor. 
  • You may want to consider sperm storage before starting Mygem 1Gm Inj. Seek counsel on the same from a qualified healthcare individual and/or sperm bank. 
  • In case of any flu-like symptoms such as fever or chills, please consult your doctor before taking any antipyretic medications or paracetamol. 

Disease/Condition Glossary

Cancer: Cancer is a disorder in which some of the cells of the body grow at an abnormal rate and spread to other parts of the body they are not originally meant to be in. Cancer is acknowledged as a genetic disease. It is most probably inherited from either parent or a blood relative. Extreme weight loss, loss of appetite, extreme lethargy, anaemia (low blood levels) and giddiness are some of the common symptoms of cancer.

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