Myo-MR Plus Tablet 10's

Written By Divya L , PharmaD

Reviewed By Veda Maddala , M Pharmacy

Prescription drug

MRP ₹144

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₹21.6 Cashback (15%)

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About Myo-MR Plus Tablet

Myo-MR Plus Tablet belongs to the class of medicine called 'muscle relaxant' in combination with a painkiller, used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

Myo-MR Plus Tablet is a combination of two drugs: Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Myo-MR Plus Tablet include nausea, vomiting, dry mouth, dizziness, weakness, and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting Myo-MR Plus Tablet . Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking Myo-MR Plus Tablet if you are pregnant or planning for pregnancy. Myo-MR Plus Tablet may cause dizziness, so drive only if you are alert and focused. Myo-MR Plus Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and Myo-MR Plus Tablet as it could lead to increased dizziness and risk of liver damage.

Uses of Myo-MR Plus Tablet

Muscle spasms.

Directions for Use

Take the tablet with or without food. Swallow it as a whole with a glass of water, do not chew or break the tablet.

Medicinal Benefits

Myo-MR Plus Tablet treats muscle spasms and consists of Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Keep out of sight and reach of children.

Side effects of Myo-MR Plus Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Low blood pressure

Muscular Weakness

Include regular exercises like weightlifting, resistance bands into your routine to build and maintain muscle mass.
Eat balanced diet rich in protein, which is essential for muscle repair and growth.
Drink plenty of water to support muscle function and prevent dehydration, which can contribute to weakness.
Always warm up before exercise and cool down afterwards to minimize muscle strain.
Gradually increase the intensity and duration of your workouts to avoid injury and promote muscle adaptation.
As you age, it's even more important to prioritize strength training to combat sarcopenia (age-related muscle loss).
Ensure adequate intake of electrolytes like potassium, magnesium, and calcium to support proper muscle function.
Eat whole foods instead of processed foods and reduce added sugars and saturated fat.

Drug Warnings

Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting Myo-MR Plus Tablet . Consult your doctor before taking Myo-MR Plus Tablet if you are pregnant, planning for pregnancy, or breastfeeding. Myo-MR Plus Tablet may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Myo-MR Plus Tablet as it could lead to increased dizziness and risk of liver damage. Myo-MR Plus Tablet is not recommended in children as safety and efficacy is not established.

Drug-Drug Interactions

ParacetamolKetoconazole

Severe

ParacetamolMipomersen

Severe

Drug-Drug Interactions

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ParacetamolKetoconazole

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Myo-MR Plus Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Myo-MR Plus Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

ParacetamolMipomersen

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Mipomersen with Myo-MR Plus Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Myo-MR Plus Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

ParacetamolLeflunomide

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Myo-MR Plus Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Myo-MR Plus Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParacetamolLomitapide

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Lomitapide and Myo-MR Plus Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Myo-MR Plus Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolOxazepam

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Myo-MR Plus Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Myo-MR Plus Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolTeriflunomide

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Teriflunomide with Myo-MR Plus Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Myo-MR Plus Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

ParacetamolKetamine

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of ketamine and Myo-MR Plus Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Myo-MR Plus Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

ParacetamolValdecoxib

Severe

How does the drug interact with Myo-MR Plus Tablet:
Co-administration of Myo-MR Plus Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Myo-MR Plus Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Exercise regularly as it helps in muscle stretching and makes muscles less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
Massages can also be helpful.
Avoid freezing and hot temperatures.
Avoid wearing tight-fitting clothes, instead, wear loose garments.
Rest well and get plenty of sleep.
To avoid developing pressure sores, change your position at least every two hours.
Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.
Stay hydrated, drink plenty of water.

Side Effects of Myo-MR Plus Tablet

Nausea
Vomiting
Dry mouth
Dizziness
Weakness
Sleepiness

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

Written By

Divya L

PharmaD

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Myo-MR Plus Tablet work?

Myo-MR Plus Tablet is a combination of two drugs: Tolperisone hydrochloride and Paracetamol. Tolperisone hydrochloride works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

Can I stop taking Myo-MR Plus Tablet if my symptoms are relieved?

Myo-MR Plus Tablet is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

Are there any specific contraindications while using Myo-MR Plus Tablet ?

Myo-MR Plus Tablet is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (muscle weakness) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting Myo-MR Plus Tablet if you have a medical history.

Should I take Myo-MR Plus Tablet with or without food?

Myo-MR Plus Tablet may cause stomach upset. Hence, you are recommended to take Myo-MR Plus Tablet with food to prevent stomach upset.

Drug-Drug Interactions Checker List

WARFARIN
METOCLOPRAMIDE
DOMPERIDONE
CHOLESTYRAMINE
IMATINIB

Special Advise

Let your doctor know that you are taking Myo-MR Plus Tablet if you are undergoing any medical tests.
Myo-MR Plus Tablet may cause fluid retention (edema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
Explain a detail history to the doctor as use of Myo-MR Plus Tablet is contraindicated in patients with myasthenia gravis.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.