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  3. Natrilix SR Tablet 10's

Natrilix SR Tablet 10's, Pack of 10 TABLETS
Natrilix SR Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

INDAPAMIDE-1.5MG

Manufacturer/Marketer :

Serdia Pharmaceuticals India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Natrilix SR Tablet

Natrilix SR Tablet belongs to a group of medicines “thiazide diuretic” primarily used for the treatment of hypertension (high blood pressure). Additionally, Natrilix SR Tablet is used to reduce the risk of heart failure and oedema (a build-up of fluid in the body). A Thiazide diuretic prevents the body from absorbing excessive salt that may cause fluid retention. Hypertension is a medical condition in which the blood exerts high pressure against the walls of blood vessels. Due to this, the heart has to work harder to pump the supply of blood in the whole body. Hypertension can put a person on severe health complications, including stroke, heart failure, heart attack, and aneurysm.

Natrilix SR Tablet contains Indapamide, and it is only available on prescription. It works by inhibiting the reabsorption of sodium in the body, resulting in an increase in chloride, sodium, and water excretion through urine. The shift in electrolytes and sodium levels reduces vascular resistance and makes the heart work normally. The production of diuresis and removal of excessive salt and fluid helps to lower blood pressure.

Natrilix SR Tablet is an orally administered drug. You can take Natrilix SR Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Sometimes, you may experience dehydration, dizziness, headache, fatigue, nausea, itching, and abdominal pain. Most of these side effects of Natrilix SR Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Natrilix SR Tablet should not be stopped even if you feel better without consulting your doctor, as stopping a sudden intake of Natrilix SR Tablet may worsen your condition and increase the risk of future heart problems. Natrilix SR Tablet may lower the potassium level in the body, so ask your doctor about how to add it to the diet. Please inform your doctor if you have had an allergic reaction to Natrilix SR Tablet , is pregnant or get pregnant, is breastfeeding, have gout, liver disease, kidney problems, heart failure, diabetes, a heart valve problem, or heart attack.

Uses of Natrilix SR Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Natrilix SR Tablet is prescribed for treating high blood pressure. Being a diuretic medication, Natrilix SR Tablet enhances the excretion of sodium and water through urine by restricting sodium absorption in the nephron tubes. If high blood pressure is not controlled for a longer time, then arteries and the heart will not be able to function properly. This may further increase the chances of damage to brain blood vessels, resulting in heart attack and serious kidney failure. However, taking Natrilix SR Tablet at the right time can control the blood pressure and make the heart function properly.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Natrilix SR Tablet can increase the chances of light-headedness so rise slowly if you are sitting and avoid operating any machine or doing any work that needs mental alertness. Before taking Natrilix SR Tablet , tell the doctor if you have any allergies to the active and inactive ingredients present in it, have a history including anuria (kidneys aren't producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma. Natrilix SR Tablet may lower down the potassium level in the body, so ask the doctor about how to add it to the diet. Natrilix SR Tablet should only be given during pregnancy when the doctor strongly suggests it. Natrilix SR Tablet could pass in the breast milk, so ask your doctor if you are a breastfeeding woman before taking it. Natrilix SR Tablet should not be given to children as safety has not been established.

Drug-Drug Interactions

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IndapamideDroperidol
Critical
IndapamideProtriptyline
Critical

Drug-Drug Interactions

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IndapamideDroperidol
Critical
How does the drug interact with Natrilix SR Tablet:
Taking Droperidol with Natrilix SR Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Natrilix SR Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Natrilix SR Tablet:
Taking Protriptyline along with Natrilix SR Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Natrilix SR Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideThioridazine
Critical
How does the drug interact with Natrilix SR Tablet:
Taking Natrilix SR Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Natrilix SR Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideDofetilide
Severe
How does the drug interact with Natrilix SR Tablet:
Co-administration of Natrilix SR Tablet with Dofetilide can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Natrilix SR Tablet and Dofetilide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, fainting, shortness of breath, rapid heartbeat, weakness, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndapamideTizanidine
Severe
How does the drug interact with Natrilix SR Tablet:
Co-administration of Tizanidine with Natrilix SR Tablet may reduce blood pressure greatly leading to side effects.

How to manage the interaction:
Although taking Natrilix SR Tablet and Tizanidine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any of these signs - feeling dizzy, having a headache, feeling lightheaded, or fainting, Consult a doctor. Do not discontinue any medications without a doctor's advice.
IndapamidePimozide
Severe
How does the drug interact with Natrilix SR Tablet:
Co-administration of Natrilix SR Tablet with Pimozide can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Natrilix SR Tablet and Pimozide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndapamideDronedarone
Severe
How does the drug interact with Natrilix SR Tablet:
When Natrilix SR Tablet and Dronedarone are taken together, the risk of an irregular heart rhythm increases.

How to manage the interaction:
Taking Natrilix SR Tablet and Dronedarone together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndapamideDolasetron
Severe
How does the drug interact with Natrilix SR Tablet:
Co-administration of Natrilix SR Tablet with Dolasetron can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Natrilix SR Tablet and Dolasetron together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult a doctor. Do not discontinue any medications without a doctor's advice.
IndapamideArsenic trioxide
Severe
How does the drug interact with Natrilix SR Tablet:
Co-administration of Natrilix SR Tablet with Arsenic trioxide can increase the risk of abnormal heart rhythms.

How to manage the interaction:
Taking Natrilix SR Tablet and Arsenic trioxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndapamideAminolevulinic acid
Severe
How does the drug interact with Natrilix SR Tablet:
Using Aminolevulinic acid with Natrilix SR Tablet, your skin becomes more sensitive to strong light. This increases your risk of getting a bad sunburn.

How to manage the interaction:
Although taking Natrilix SR Tablet and Aminolevulinic acid together can cause an interaction, it can be taken if a doctor has suggested it. After treatment, you should wait 48 hours before exposing your eyes, and skin, to any bright lights indoors. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Natrilix SR Tablet Substitute

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Author Details

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Written By

Urvashi Bharti

MBBS

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:30 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Natrilix SR Tablet belongs to the group of medicines called diuretics that increase the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Unless suggested by the doctor, to take Natrilix SR Tablet in morning or night, one should fix a time slot, and they should take it regularly at the same time. However, one should avoid taking it at night time or just before bed as this medicine causes frequent urination. So, best to take it before 4 hours going to bed.

As hypertension is a serious medical issue, so taking Natrilix SR Tablet help to reduce the risk of heart disease and other serious conditions. So, one should not stop taking medicine without consulting with their doctor. However, depending upon the condition, the doctor will adjust the dosing.

Even if a person achieved their goal of bringing their blood pressure back to normal, they should not stop taking it without asking a doctor. Only after the doctor's recommendation, the dosage of Natrilix SR Tablet could be adjusted.

Yes, prolonged intake of Natrilix SR Tablet may decrease your potassium levels in the bloodstream. So, it is better to ask your doctor about foods high in potassium like bananas or orange juice. Besides this, consult a doctor regarding the use of table salt or sodium chloride, or salt substitute containing potassium.

Natrilix SR Tablet comes under the category of diuretics, so it is formulated to increase the amount of water in the body to expel the excessive sodium present in the body through urine. In this way, it helps to maintain normal blood pressure.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • TORSEMIDE
  • AMLODIPINE
  • RAMIPRIL
  • BACLOFEN
  • LEVODOPA
  • CLONIDINE
  • AMBROXOL
  • LITHIUM
  • RISPERIDONE
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

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