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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nausetil Inj

Nausetil Inj belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety. Additionally, it is used to treat symptoms of nausea and vomiting, and vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave properly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities.

Nausetil Inj contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Nausetil Inj has a calming effect on people suffering from anxiety or mania. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting. 

Nausetil Inj will be administered by a healthcare professional. Do not self-administer. Some people may experience dry mouth, drowsiness, dizziness, blurred vision, and orthostatic hypotension (low blood pressure when standing up from sitting or lying down) as side effects of Nausetil Inj. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Nausetil Inj if you are known to be allergic to it. Nausetil Inj should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Nausetil Inj is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Nausetil Inj. Avoid consumption of alcohol with Nausetil Inj as it may increase adverse effects. Avoid exposure to direct sunlight while taking Nausetil Inj as it may cause skin more sensitive to sunlight. If this injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). 

Uses of Nausetil Inj

Schizophrenia, acute mania, short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness) due to inner ear problems such as Meniere’s syndrome or labyrinthitis. 

Directions for Use

Nausetil Inj will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Nausetil Inj contains Prochlorperazine used to reduce symptoms of major mental disorders such as schizophrenia, acute mania, and short-term treatment of anxiety. It decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Nausetil Inj has a calming effect on people suffering from anxiety or mania. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting. Additionally, it is used to treat symptoms of vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nausetil Inj
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Drug Warnings

Do not take Nausetil Inj if you are known to be allergic to Nausetil Inj. Nausetil Inj should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Nausetil Inj is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Nausetil Inj. Avoid consumption of alcohol with Nausetil Inj as it may increase adverse effects. Avoid exposure to direct sunlight while taking Nausetil Inj as it may cause skin more sensitive to sunlight. If the injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Nausetil Inj. 

Drug-Drug Interactions

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ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMesoridazine
Critical
How does the drug interact with Nausetil Inj:
Coadministration of mesoridazine and Nausetil Inj can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Nausetil Inj is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nausetil Inj:
Coadministration of metoclopramide and Nausetil Inj can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Nausetil Inj together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nausetil Inj:
Coadministration of Nausetil Inj and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Coadministration of Nausetil Inj and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Nausetil Inj:
Coadministration of Nausetil Inj with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Nausetil Inj with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Nilotinib together can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Nausetil Inj and Nilotinib, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Anagrelide together can increase the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Nausetil Inj and anagrelide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nausetil Inj:
Taking Arsenic trioxide and Nausetil Inj together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Arsenic trioxide with Nausetil Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. You should contact your doctor immediately if you experience fainting, irregular heartbeats, prolonged diarrhoea or vomiting, sudden dizziness, lightheadedness, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Disopyramide with Nausetil Inj can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a fast or irregular heartbeat, dizziness, fainting, shortness of breath, or severe diarrhoea or vomiting, it's important to call your doctor right away. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Droperidol together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Nausetil Inj with Droperidol can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Escitalopram together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nausetil Inj with Escitalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food, like flavoured gelatin and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nausetil Inj contains Prochlorperazine, an antipsychotic drug that decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting.

Yes, Nausetil Inj may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).

Nausetil Inj may cause photosensitivity (extreme sensitivity to sunlight) if used in high doses. Therefore, avoiding exposure to direct sunlight while taking Nausetil Inj is recommended.

Nausetil Inj should be used with caution in diabetes patients as it may increase blood sugar levels. Therefore, if you are diabetic, regular monitoring of blood sugar levels is recommended while on treatment with Nausetil Inj.

Nausetil Inj may cause low blood pressure in some patients while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Therefore, to avoid such side effects, you are recommended to get up slowly after lying down or sitting.

Drug-Drug Interactions Checker List

  • PHENOBARBITAL
  • CLONIDINE
  • GUANETHIDINE
  • ATROPINE
  • PROCYCLIDINE
  • LITHIUM
  • DESFERRIOXAMINE
  • LEVODOPA
  • ADRENALINE
  • PROPRANOLOL
  • AMPHETAMINE

Special Advise

Avoid exposure to direct sunlight while taking Nausetil Inj as it may cause skin more sensitive to sunlight.

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

Schizophrenia: It is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Mania: It is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep patterns, high levels of stress, and alcohol intake.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities. The symptoms of anxiety include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.

Meniere’s syndrome: It is a disorder of the inner ear that causes vertigo (spinning), hearing loss, and ringing in the ears.  

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