Nebifine-AM Tablet 10's is a combination of blood pressure-lowering medicine primarily used to treat high blood pressure and reduce the further risk of heart attack or stroke. Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. Nebifine-AM Tablet 10's lowers your blood pressure and reduces the risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Nebifine-AM Tablet 10's is a combination of S Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker). S Amlodipine acts by relaxing the blood vessels and reducing the heart's workload, and making the heart more efficient at pumping blood throughout the body. Nebivolol helps in relaxing the blood vessels by blocking the action of certain natural substances in the body.

Take Nebifine-AM Tablet 10's as prescribed by your doctor. You are advised to take Nebifine-AM Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition.  Some people may experience headaches, feeling exhausted and swollen ankles. Most of these side effects of Nebifine-AM Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Nebifine-AM Tablet 10's as it can increase the concentration of Nebifine-AM Tablet 10's in the blood and worsen its side effects. Please inform your doctor if you have had an allergic reaction to Nebifine-AM Tablet 10's, are pregnant, plan to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, diabetes, a heart valve problem, or heart attack. Reducing the amount of table salt will happen.

Nebifine-AM Tablet 10's is a combination of two medicines: S Amlodipine and Nebivolol, which help lower raised blood pressure effectively. S Amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Nebivolol (beta-blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective. 

• Bradycardia (slow heart rate)
• Increased blood potassium level
• Cold extremities
• Gastrointestinal disturbances 
• Nausea
• Fatigue

Don't stop taking Nebifine-AM Tablet 10's without talking to your doctor first. Stopping Nebifine-AM Tablet 10's abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Nebifine-AM Tablet 10's if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to children less than 6 years of age. Before taking Nebifine-AM Tablet 10's, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome). Prolonged intake of Nebifine-AM Tablet 10's may lead to a lowering of blood pressure. So, you must closely monitor your blood pressure if you ever have had a stroke, heart attack, or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor.

Drug-Drug Interaction: Nebifine-AM Tablet 10's may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, sotalol), causing a dangerous drop in the heart rate. It also reacts with other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem). Besides this, Nebifine-AM Tablet 10's should not be used with other asthma medications (theophylline, aminophylline), potassium-rich supplements, or other painkillers (ibuprofen). If you are using these medicines, tell your doctor before taking Nebifine-AM Tablet 10's.

Drug-Food Interaction: Nebifine-AM Tablet 10's is known to interact with grapefruit and protein-enriched foods. Using Nebifine-AM Tablet 10's together with ayurvedic, homeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of Nebifine-AM Tablet 10's. Hence, it is better to maintain at least 2 hours gap between the administration of Nebifine-AM Tablet 10's and these products.

Drug-Disease Interaction: Nebifine-AM Tablet 10's should not be given to people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.

• ALISKIREN
• AMILORIDE
• ENALAPRIL
• CAPTOPRIL
• QUINAPRIL
• DILITAZEM
• THEOPHYLLINE
• AMINOPHYLLINE
• IBUPROFEN
• POTASSIUM
• ATENOLOL
• ACEBUTOLOL
• BISOPROLOL
• CARTEOLOL
• ESMOLOL
• METOPROLOL
• NADOLOL
• SOTALOL

• Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• If you are taking alcohol, then only one serving for women and two servings for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
• Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.