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Lupin Ltd

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About Nebistar LN 2.5/10mg Tablet

Nebistar LN 2.5/10mg Tablet belongs to a class of medications called 'Anti hypertensives' primarily used to treat high blood pressure. Nebistar LN 2.5/10mg Tablet is a combination of two drugs namely Cilnidipine (Calcium channel blocker) & Nebivolol (Beta blocker). Hypertension is a disease associated with increased blood pressure inside blood vessels. Hypertension is a long-term disease that can lead to complications like heart attack, heart stroke & long-term kidney diseases.

Nebistar LN 2.5/10mg Tablet is a combination of two medicines: Cilnidipine & Nebivolol, which help lower raised blood pressure effectively. Cilnidipine is a blood pressure-lowering drug belonging to the family of calcium channel blockers. It helps to control blood pressure by blocking action at the N-type calcium channel which dilates both arteriole & venules as a result the pressure in the capillary bed is reduced. This allows the blood to flow more smoothly and the heart to pump more efficiently. Nebivolol is another blood pressure lowering drug that belongs to a class called beta blockers, it works by relaxing blood pressure & slowing heart rate to improve blood circulation and decrease blood pressure. Together, they are used to treat patients with hypertension who cant be treated with a single drug. 

You can take Nebistar LN 2.5/10mg Tablet with food or without food. It should be swallowed with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience headache, nausea, dizziness, Tiredness, increased potassium level, constipation, edema,  Cold extremities, and low blood pressure. Most of these side effects of Nebistar LN 2.5/10mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of getting heart disease and stroke. Inform your doctor if you are suffering from any kidney or liver or heart disease or are diabetic. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Nebistar LN 2.5/10mg Tablet can be prescribed accordingly. It should not be given to children less than 12 years of age. Do not use Nebistar LN 2.5/10mg Tablet if you have low blood pressure (hypotension), or cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to Nebistar LN 2.5/10mg Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. It would be best to have regular potassium and electrolytes level check-ups while taking Nebistar LN 2.5/10mg Tablet to prevent any complications.

Uses of Nebistar LN 2.5/10mg Tablet

Hypertension (high blood pressure).

Directions for Use

Take Nebistar LN 2.5/10mg Tablet with or without food or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Nebistar LN 2.5/10mg Tablet is primarily used to treat hypertension (high blood pressure). It is a combination of two medicines: Cilnidipine & Nebivolol, which help lower raised blood pressure effectively. Cilnidipine is a calcium channel blocker that acts by relaxing blood vessels thus decreasing the blood pressure to normal levels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Nebivolol is a beta blocker that helps in relaxing our heart by blocking the action of certain natural substances in your body. This lowers your blood pressure and reduces your risk of having a future stroke, a heart attack, other heart problems or kidney problems in the future. This medicine needs to be taken regularly to be effective.

Side effects of Nebistar LN 2.5/10mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Talk to your doctor or pharmacist before taking Nebistar LN 2.5/10mg Tablet if you experience shortness of breath or dizziness or abnormally slow heart rate, have heart diseases due to decreased blood flow to heart muscles, have poor blood flow towards extremities of body such as finger, hands, and feet (Raynaud’s disease), experience pain, tension and weakness in the legs when walking which is relieved by rest, have a persistent obstruction of your airway such as chronic bronchitis, have diabetes, as it can hide the warning signs of low sugar levels or overactivity of the thyroid gland (hyperthyroidism). Also, inform your doctor if you are being treated with any other drugs which lower your blood pressure.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Taking Disopyramide and Nebistar LN 2.5/10mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Disopyramide and Nebistar LN 2.5/10mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Coadministration of Atenolol and Nebistar LN 2.5/10mg Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Atenolol and Nebistar LN 2.5/10mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
NebivololSaquinavir
Severe
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Using saquinavir together with Nebistar LN 2.5/10mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking saquinavir together with Nebistar LN 2.5/10mg Tablet can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, slow pulse, irregular heartbeat, contact a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Taking Fingolimod and Nebistar LN 2.5/10mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Fingolimod and Nebistar LN 2.5/10mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Combined use of Nebistar LN 2.5/10mg Tablet with Theophylline may increase the effect of Theophylline.

How to manage the interaction:
Although there is a possible interaction between Theophylline and Nebistar LN 2.5/10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, irregular heartbeats, contact a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Coadministration of atazanavir with Nebistar LN 2.5/10mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking atazanavir with Nebistar LN 2.5/10mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, or irregular heartbeat consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Taking Nebistar LN 2.5/10mg Tablet with Diltiazem may increase the risk or severity of side effects.

How to manage the interaction:
Taking Nebistar LN 2.5/10mg Tablet with Diltiazem together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fatigue, headache, fainting, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, contact a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Coadministration ceritinib with Nebistar LN 2.5/10mg Tablet can slow your heart rate and increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking ceritinib with Nebistar LN 2.5/10mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Coadministration of Nebistar LN 2.5/10mg Tablet with Theophylline may reduce the effect of Nebistar LN 2.5/10mg Tablet.

How to manage the interaction:
Taking Nebistar LN 2.5/10mg Tablet with Theophylline together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebistar LN 2.5/10mg Tablet:
Combine use of Nebistar LN 2.5/10mg Tablet and Ritodrine may decrease the effect of Nebistar LN 2.5/10mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nebistar LN 2.5/10mg Tablet and Ritodrine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience Nausea, Headache, Fatigue, Constipation, Diarrhea, Dizziness, contact a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease. Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Side Effects of Nebistar LN 2.5/10mg Tablet

  • Headache
  • Slow heart rate
  • Constipation
  • Cold extremities
  • Nausea
  • Sleepiness
  • Tiredness
  • Palpitations
  • Ankle swelling
  • Flushing (warm cheeks, necks, ears)

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for aforgotten dose.

No, stopping the treatment without doctor's consultation may cause blood pressure to rise again, putting the person at risk for stroke and other complications of hypertension.

Nebistar LN 2.5/10mg Tablet and contraceptives as such are safe to use as no interaction between them has been reported, yet doctors consultation is recommended

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • RIFAMPICIN
  • ERYTHROMYCIN
  • QUINIDINE

Special Advise

  • Do not take this drug if you are allergic to either component of the drug.
  • Do not take if a patient has a tumor in the adrenal gland, has asthma or wheezing (now or in the past)
  • Keep consulting with your doctor for occasional checkups  & dose adjustments.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. You can have high blood pressure (hypertension) for years without any symptoms. Even without symptoms, damage to blood vessels and your heart continues and can be detected. Uncontrolled high blood pressure increases your risk of serious health problems, including heart attack and stroke. High blood pressure generally develops over many years, and it affects nearly everyone eventually. Fortunately, high blood pressure can be easily detected. And once you know you have high blood pressure, you can work with your doctor to control it.

Have a query?

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Alcohol

Caution

Taking this drug with alcohol may lead to decreased blood pressure thus not recommended.

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Pregnancy

Unsafe

Should not be used during pregnancy, unless clearly necessary. Consult a doctor before taking the medicine.

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Breast Feeding

Caution

Doctors consultation is recommended as there is no data available whether this drug is passed through mothers milk to infant.

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Driving

Caution

It may cause sleepiness and drowsiness thus not used before driving.

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Liver

Caution

Mild side effects have been reported with the use of Nebistar LN 2.5/10mg Tablet , thus doctor's consultation is required with its use.

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Kidney

Caution

patients with kidney problem should consult a doctor before taking this medication as this drug may affect blood circulation to the kidneys

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Children

Unsafe

Not to be used in children below 12 years as there have been cases of harmful interactions.

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