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  3. Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy
COD available

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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) belongs to the group of medicines called bronchodilators indicated for long-term, maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the bronchial tube lining). 
 
Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is a combination of two medicines, namely: Arformoterol (long-acting beta2-adrenergic agonist) and Glycopyrronium (anti-cholinergic). Arformoterol prevents tightening of the muscles in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.
 
You are advised to use Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, dry mouth, chest pain, muscle cramps, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not stop using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) on your own as it might cause worsening of symptoms. Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are pregnant or breastfeeding. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not recommended for children below 18years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.

Uses of Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Chronic Obstructive Pulmonary Disease (COPD).

Directions for Use

Smartule: Check the instruction leaflet before use. It should be used with a nebuliser only in the dose and duration prescribed by a doctor. It is not to be injected or administered orally. Open the smartule by twisting off the cap. Squeeze the content into the reservoir of the nebulising chamber. Discard the smartule after use. Any invisible damage caused during transit or storage may cause contamination. Do not use the smartule if the suspension is discolored, has any leaks upon squeezing or contains visible black particles.

Medicinal Benefits

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is a combination of two medicines, namely: Arformoterol and Glycopyrronium. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) belongs to the group of medicines called bronchodilators used to treat Chronic Obstructive Pulmonary Disease (COPD). Arformoterol is a long-acting beta-agonist that prevents tightening of the muscles in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium is an anti-cholinergic that decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are allergic to any of its contents. Inform your doctor if you have asthma, heart problems, seizures/epilepsy, thyroid gland problems, diabetes, narrow-angle glaucoma, kidney problems, severe liver problems, if you have any difficulty in passing urine or if you are taking any medicines for lung diseases. Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are pregnant or breastfeeding. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not recommended for children below 18years as the safety and effectiveness have not been established. 

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Co-administration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium citrate can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium chloride can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium chloride together is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Coadministration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, fatigue, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Coadministration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Topiramate can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Topiramate together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, fever, chills, or decreased sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking ribociclib together with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Ribociclib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, contact your doctor right away. Do not stop using any medications without first talking to your doctor.
FormoterolCarteolol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking carteolol with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can reduce the effects of both drugs.

How to manage the interaction:
Although there is an interaction between Carteolol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Using epinephrine together with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) and Epinephrine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolNadolol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking nadolol with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) together could decrease the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) and Nadolol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPindolol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with pindolol together could decrease the effects of both medications.

How to manage the interaction:
Although there is an interaction between Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) and Pindolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Coadministration of propranolol with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can reduce the effects of both medications.

How to manage the interaction:
Although taking propranolol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen symptoms.
  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an attack.
  • Quit smoking as it may reduce the effectiveness of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), irritate the lungs and worsen breathing problems.
  • Learn breathing exercises like pursed-lip breathing. It helps provide relief from COPD.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) contains Arformoterol and Glycopyrronium. Arformoterol relaxes and widens the openings in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is indicated for the maintenance treatment for COPD. It does not treat a sudden attack of wheezing or breathlessness. Use a rescue inhaler to treat sudden breathing problems.

Dry mouth could be a side-effect of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ). Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, and drinking water regularly can help cope with dry mouth.

Do not stop using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) on your own as it might cause worsening of symptoms. To treat your condition effectually, continue using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) for as long as your doctor has prescribed it. Talk to your doctor if your breathing problems, wheezing, or cough do not improve or worsen.

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not indicated for the treatment of asthma as the safety and effectiveness of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) in patients with asthma have not been established. Consult your doctor if you have asthma.

Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are diabetic, as it might sometimes raise blood sugar levels. Regular monitoring of blood glucose levels whilst using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is advised.

Drug-Drug Interactions Checker List

  • SALMETEROL
  • SALBUTAMOL
  • ALBUTEROL
  • IPRATROPIUM
  • FORMOTEROL
  • BUDESONIDE
  • FLUTICASONE
  • DARIFENACIN
  • OXYBUTYNIN

Disease/Condition Glossary

Chronic Obstructive Pulmonary Disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may also lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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