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  3. Neftrol 0.25Mcg Softgel Capsule 10'S

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Composition :

CALCITRIOL-0.25MCG

Manufacturer/Marketer :

Chemo Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Neftrol 0.25Mcg Softgel Capsule

Neftrol 0.25Mcg Softgel Capsule belongs to a group of medicines called ‘vitamin D metabolites’ primarily used to treat low blood calcium levels. Neftrol 0.25Mcg Softgel Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Neftrol 0.25Mcg Softgel Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Neftrol 0.25Mcg Softgel Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Neftrol 0.25Mcg Softgel Capsule contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Take Neftrol 0.25Mcg Softgel Capsule as prescribed by your doctor. You are advised to take Neftrol 0.25Mcg Softgel Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Neftrol 0.25Mcg Softgel Capsule can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Neftrol 0.25Mcg Softgel Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Neftrol 0.25Mcg Softgel Capsule or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Neftrol 0.25Mcg Softgel Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Neftrol 0.25Mcg Softgel Capsule may pass into the breast milk, hence breastfeeding mothers need to seek medical advice before starting Neftrol 0.25Mcg Softgel Capsule . Do not take Neftrol 0.25Mcg Softgel Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.

Uses of Neftrol 0.25Mcg Softgel Capsule

Osteoporosis (weak and brittle bones)Osteomalacia/rickets (weak bones)Hypoparathyroidism (low levels of parathyroid hormone)Latent tetany (a muscle disease with low blood calcium levels)

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Neftrol 0.25Mcg Softgel Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Neftrol 0.25Mcg Softgel Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Neftrol 0.25Mcg Softgel Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Storage

Keep Neftrol 0.25Mcg Softgel Capsule out of the sight and reach of children.
Side effects of Neftrol 0.25Mcg Softgel Capsule
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Reduce sodium intake to minimize calcium excretion in urine.
  • Limit animal protein consumption to decrease urinary calcium levels.
  • Increase fluid intake by drinking plenty of water to dilute urine.
  • Moderate calcium intake based on individual needs, avoiding drastic restriction.
  • Limit oxalate-rich foods like spinach and chocolate to minimize kidney stone formation.
  • Stay hydrated by drinking plenty of water.
  • Consider reducing vitamin D supplementation if excessive intake is contributing to hypercalciuria.
  • Regularly monitor urine calcium levels through 24-hour urine tests.
  • Always seek guidance from a healthcare expert prior to implementing substantial changes to your diet or lifestyle routine.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Before taking Neftrol 0.25Mcg Softgel Capsule , inform your doctor if you are undergoing hemodialysis due to kidney problems and have a stent in the heart. Neftrol 0.25Mcg Softgel Capsule may alter calcium levels, so it is recommended to regularly monitor calcium levels in the blood and urine. Inform your doctor immediately if you notice fever, increased thirst and urination, dehydration, bedwetting, constipation, and stomach pain, as they may sign very high levels of calcium in your blood. Pregnant or breastfeeding women should consult their doctor before taking Neftrol 0.25Mcg Softgel Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Neftrol 0.25Mcg Softgel Capsule may pass into the breast milk, hence breastfeeding mothers need to seek medical advice before starting Neftrol 0.25Mcg Softgel Capsule . Do not take Neftrol 0.25Mcg Softgel Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Neftrol 0.25Mcg Softgel Capsule with Carbamazepine may decrease the effects of Neftrol 0.25Mcg Softgel Capsule.

How to manage the interaction:
Although there is an interaction, Neftrol 0.25Mcg Softgel Capsule can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Isoniazid with Neftrol 0.25Mcg Softgel Capsule may decrease the effects of Neftrol 0.25Mcg Softgel Capsule.

How to manage the interaction:
Although there is an interaction, Neftrol 0.25Mcg Softgel Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Cholecalciferol and Neftrol 0.25Mcg Softgel Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Neftrol 0.25Mcg Softgel Capsule, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Ergocalciferol and Neftrol 0.25Mcg Softgel Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Neftrol 0.25Mcg Softgel Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Paricalcitol and Neftrol 0.25Mcg Softgel Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Neftrol 0.25Mcg Softgel Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Taking Neftrol 0.25Mcg Softgel Capsule with Fosphenytoin can reduce the levels and efficacy of Neftrol 0.25Mcg Softgel Capsule.

How to manage the interaction:
Taking Neftrol 0.25Mcg Softgel Capsule with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Calcifediol and Neftrol 0.25Mcg Softgel Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Neftrol 0.25Mcg Softgel Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Metolazone with Neftrol 0.25Mcg Softgel Capsule can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Neftrol 0.25Mcg Softgel Capsule can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Amobarbital and Neftrol 0.25Mcg Softgel Capsule may decrease the effects of Neftrol 0.25Mcg Softgel Capsule.

How to manage the interaction:
Co-administration of Neftrol 0.25Mcg Softgel Capsule with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Neftrol 0.25Mcg Softgel Capsule:
Co-administration of Rifapentine with Neftrol 0.25Mcg Softgel Capsule may decrease the effects of Neftrol 0.25Mcg Softgel Capsule.

How to manage the interaction:
Although there is an interaction, Neftrol 0.25Mcg Softgel Capsule can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Side Effects of Neftrol 0.25Mcg Softgel Capsule

  • Hypercalcaemia (high calcium levels in the blood)
  • Loss of appetite
  • Weight loss
  • Feeling sick
  • Being sick
  • Headache and feeling sluggish
  • Drowsy or weak
  • Stomach pain or discomfort
  • Urinary tract infection
  • Rash

Habit Forming

No

Therapeutic Class

MULTIMINERALS

Author Details

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Drug-Diseases Interactions

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CALCITRIOL-0.25MCGOther cardiac arrhythmias
Severe
CALCITRIOL-0.25MCGDisorders of mineral metabolism
Severe

Drug-Diseases Interactions

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CALCITRIOL-0.25MCGOther cardiac arrhythmias
Severe
How does the disease interact with Neftrol 0.25Mcg Softgel Capsule:
Vitamin D analogues work to raise serum calcium levels and can make arrhythmias worse, especially in people on cardiac glycosides.

How to manage the interaction:
Neftrol 0.25Mcg Softgel Capsule increases serum calcium concentrations and may worsen arrhythmia, particularly in patients receiving cardiac glycosides. Neftrol 0.25Mcg Softgel Capsule should be administered cautiously in patients with arrhythmia. Monitoring of serum electrolyte concentrations and cardiac function is advised.
CALCITRIOL-0.25MCGDisorders of mineral metabolism
Severe
How does the disease interact with Neftrol 0.25Mcg Softgel Capsule:
The use of vitamin D analogues like calciferol and ergocalciferol in individuals with hypercalcemia, malabsorption syndrome, or signs of vitamin D toxicity is not advised.

How to manage the interaction:
Serum electrolyte concentration should be corrected prior to therapy and monitored during therapy with Neftrol 0.25Mcg Softgel Capsule.
CALCITRIOL-0.25MCGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Neftrol 0.25Mcg Softgel Capsule:
Renal biotransformation of ergocalciferol, cholecalciferol, and calcifediol occurs during metabolic activation. Certain vitamin D analogues' therapeutic and metabolic effects may be affected by renal impairment.

How to manage the interaction:
Renal impairment can alter metabolic and therapeutic activity of certain vitamin D analogs. Alternative vitamin D analogs may be considered in patients with compromised renal function.
CALCITRIOL-0.25MCGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Neftrol 0.25Mcg Softgel Capsule:
In order to maintain proper phosphorus levels and prevent ectopic calcification in individuals with renal impairment, vigilance should be exercised because Neftrol 0.25Mcg Softgel Capsule increases inorganic phosphate levels in serum.

How to manage the interaction:
Caution is advised in patients with kidney impairment to maintain adequate phosphorus levels and avoid ectopic calcification.

FAQs

Neftrol 0.25Mcg Softgel Capsule contains calcitriol, and it works by making your body absorb more calcium from your diet. This helps to form healthy bones and reduce bone damage.

Neftrol 0.25Mcg Softgel Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Neftrol 0.25Mcg Softgel Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.

Neftrol 0.25Mcg Softgel Capsule is used to increase low levels of calcium in the body. Hence it is not advised to use Neftrol 0.25Mcg Softgel Capsule during hypercalcemia since it causes the overdose of calcium leading to kidney stones and other effects.

Preferably, supplements of vitamin D3 should be taken along with the day's main meal or with milk.

Do not use Neftrol 0.25Mcg Softgel Capsule if you ate allergic to Neftrol 0.25Mcg Softgel Capsule or any other ingredients in it. Neftrol 0.25Mcg Softgel Capsule is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Drug-Drug Interactions Checker List

  • HYDROCORTISONE
  • PREDNISOLONE
  • CHOLESTYRAMINE
  • DIGOXIN
  • DIGITOXIN
  • BENDROFLUMETHIAZIDE
  • CHLORTALIDONE
  • INDAPAMIDE

Special Advise

  • Neftrol 0.25Mcg Softgel Capsule is not indicated in patients with or with a history of kidney stones, as it may increase the chance of kidney stone formation. Consult your doctor for further advice.
  • Your doctor may advise regular monitoring of calcium levels.

Disease/Condition Glossary

Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially with older patients. Women are much more likely to develop osteoporosis than are men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, a bone that breaks much more quickly than expected.

Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.

Tetany: A disease condition due to low calcium levels (hypocalcemia) in the body causes cramps and spasms in the hands, feet, and larynx (voice box).

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